In situ hybridization per specimen initial single probe stain cost at US hospitals
HC in Situ Hybridization per Specimen Initial Single Probe Stain · CPT 88365
$21.50
lowest cash price
$338.40
national median
$3,057.35
highest cash price
906
hospitals with a published cash price
Middle half of hospitals (25th–75th percentile) against the full range. The same procedure varies $21.50–$3,057.35 — the variation is the story.
Median cash price over time
Sep 1, 2025 ($353.55) → Sep 1, 2026 ($375.41)
By state
| State | Hospitals | Lowest cash | Median | Highest |
|---|---|---|---|---|
| Alaska | 5 | $143.64 | $171.60 | $1,567.02 |
| Arizona | 23 | $65.38 | $159.62 | $603.56 |
| Arkansas | 10 | $54.00 | $234.65 | $627.00 |
| California | 86 | $22.80 | $228.99 | $549.85 |
| Colorado | 14 | $169.59 | $1,813.00 | $2,404.59 |
| Florida | 81 | $43.97 | $455.16 | $2,743.40 |
| Georgia | 25 | $83.18 | $732.42 | $1,963.89 |
| Hawaii | 2 | $160.32 | $160.32 | $435.00 |
| Illinois | 42 | $81.25 | $476.40 | $1,144.50 |
| Indiana | 26 | $188.50 | $902.40 | $1,336.80 |
| Iowa | 26 | $204.10 | $471.20 | $712.00 |
| Kansas | 10 | $903.66 | $1,152.53 | $1,152.53 |
| Kentucky | 22 | $56.00 | $165.70 | $1,283.03 |
| Louisiana | 2 | $136.50 | $136.50 | $136.50 |
| Maine | 7 | $105.90 | $424.00 | $1,100.90 |
| Maryland | 2 | $243.60 | $243.60 | $243.60 |
| Michigan | 27 | $75.20 | $364.00 | $607.20 |
| Minnesota | 18 | $340.00 | $979.20 | $2,344.38 |
| Mississippi | 7 | $58.74 | $72.87 | $386.64 |
| Missouri | 16 | $154.55 | $214.50 | $1,274.43 |
| Montana | 2 | $275.20 | $275.20 | $288.80 |
| Nebraska | 13 | $126.00 | $310.80 | $535.50 |
| Nevada | 3 | $96.35 | $106.69 | $134.42 |
| New Hampshire | 1 | $353.55 | $353.55 | $353.55 |
| New Jersey | 21 | $47.60 | $140.68 | $201.80 |
| New Mexico | 1 | not published by hospital | not published by hospital | not published by hospital |
| New York | 23 | $202.78 | $202.78 | $1,240.00 |
| North Carolina | 14 | $139.00 | $436.88 | $1,846.00 |
| North Dakota | 4 | $338.40 | $338.40 | $372.00 |
| Ohio | 67 | $165.60 | $396.75 | $752.70 |
| Oklahoma | 12 | $100.65 | $240.83 | $432.00 |
| Oregon | 12 | $107.87 | $501.00 | $717.40 |
| Pennsylvania | 30 | $76.20 | $337.20 | $981.00 |
| South Carolina | 11 | $241.00 | $279.00 | $811.00 |
| South Dakota | 7 | $340.00 | $407.20 | $483.20 |
| Tennessee | 37 | $61.80 | $134.85 | $2,108.96 |
| Texas | 116 | $103.60 | $353.40 | $3,057.35 |
| Virginia | 41 | $132.25 | $298.00 | $1,785.00 |
| Washington | 32 | $150.50 | $247.00 | $716.80 |
| West Virginia | 16 | $21.50 | $263.00 | $921.00 |
| Wisconsin | 35 | $175.43 | $322.50 | $1,291.51 |
| Wyoming | 4 | $143.64 | $195.05 | $274.86 |
All hospitals
| Hospital | Location | Cash price | Negotiated range |
|---|---|---|---|
| HSHS St. Nicholas Hospital | SHEBOYGAN, WI | $493.68 | $58.17 – $374.88 |
| HSHS St. Vincent Hospital | Green Bay, WI | $493.68 | $60.31 – $372.34 |
| HSHS St. Clare Memorial Hospital | OCONTO FALLS, WI | $493.68 | $174.06 – $279.60 |
| OSF Little Company of Mary Medical Center | Evergreen Park, IL | $498.60 | $67.90 – $339.58 |
| HCA FLORIDA FORT WALTON-DESTIN HOSPITAL | NAVARRE, FL | $499.20 | $149.16 – $292.21 |
| Community Hospital San Bernardino | San Bernardino, CA | $499.31 | $60.50 – $437.90 |
| Providence Newberg Medical Center | Newberg, OR | $501.00 | $151.82 – $346.55 |
| Providence Seaside Hospital | Seaside, OR | $501.00 | not published |
| Providence Portland Medical Center | Portland, OR | $501.00 | $134.61 – $613.76 |
| Providence St Vincent Medical Center | Portland, OR | $501.00 | $134.61 – $613.76 |
| Providence Willamette Falls Medical Center | Oregon City, OR | $501.00 | $134.61 – $613.76 |
| Ascension St. Vincent Kokomo (St. Joseph Hospital & Health Center, Inc.) | Kokomo, IN | $501.00 | $18.33 – $195.81 |
| Providence Milwaukie Hospital | Milwaukie, OR | $501.00 | $134.61 – $613.76 |
| Rappahannock General Hospital | Kilmarnock, VA | $502.80 | not published |
| Jewish Hospital | Cincinnati, OH | $506.40 | not published |
| Anderson Hospital | Cincinnati, OH | $506.40 | not published |
| Clermont Hospital | Batavia, OH | $506.40 | not published |
| Kings Mills Hospital | Mason, OH | $506.40 | not published |
| Fairfield Hospital | Fairfield, OH | $506.40 | not published |
| Mercy West Hospital | Cincinnati, OH | $506.40 | not published |
| Texas Health Huguley Hospital Fort Worth South | Burleson, TX | $507.71 | $143.50 – $342.86 |
| NewYork-Presbyterian Columbia University Irving Medical Center | New York, NY | $508.00 | $20.00 – $253.46 |
| WellSpan Gettysburg Hospital | Gettysburg, PA | $511.20 | $14.42 – $710.65 |
| UPMC Muncy | Muncy, PA | $512.40 | $14.77 – $170.91 |
| cleveland clinic florida weston hospital | Weston, FL | $512.85 | $24.91 – $379.00 |
| martin north hospital | Stuart, FL | $512.85 | $45.28 – $251.93 |
| MEDICAL CITY ARLINGTON HOSPITAL | RED OAK, TX | $514.96 | $149.16 – $532.78 |
| OSF Saint Clare Medical Center | Princeton, IL | $517.60 | not published |
| Fresno Medical Center | FRESNO, CA | $520.80 | $184.00 – $184.00 |
| Redwood City Medical Center | Redwood City, CA | $520.80 | $184.00 – $184.00 |
| Oakland Medical Center | Oakland, CA | $520.80 | $184.00 – $184.00 |
| Sacramento Medical Center | SACRAMENTO, CA | $520.80 | $184.00 – $184.00 |
| San Leandro Medical Center | SAN LEANDRO, CA | $520.80 | $184.00 – $184.00 |
| Santa Clara Medical Center | SANTA CLARA, CA | $520.80 | $184.00 – $184.00 |
| San Rafael Medical Center | SAN RAFAEL, CA | $520.80 | $184.00 – $184.00 |
| Santa Rosa Medical Center | SANTA ROSA, CA | $520.80 | $184.00 – $184.00 |
| South San Francisco Medical Center | SOUTH SAN FRANCISCO, CA | $520.80 | $184.00 – $184.00 |
| South Sacramento Medical Center | SACRAMENTO, CA | $520.80 | $184.00 – $184.00 |
| Vacaville Medical Center | VACAVILLE, CA | $520.80 | $184.00 – $184.00 |
| Walnut Creek Medical Center | WALNUT CREEK, CA | $520.80 | $184.00 – $184.00 |
| Vallejo Medical Center | VALLEJO, CA | $520.80 | $184.00 – $184.00 |
| Antioch Medical Center | ANTIOCH, CA | $520.80 | $184.00 – $184.00 |
| Fremont Medical Center | FREMONT, CA | $520.80 | $184.00 – $184.00 |
| Roseville Medical Center | ROSEVILLE, CA | $520.80 | $184.00 – $184.00 |
| San Jose Medical Center | SAN JOSE, CA | $520.80 | $184.00 – $184.00 |
| San Francisco Medical Center | SAN FRANCISCO, CA | $520.80 | $184.00 – $184.00 |
| SSM Health St. Mary's Hospital - Madison | Madison, WI | $521.40 | $124.11 – $754.99 |
| MercyOne Genesis Davenport Medical Center | Davenport, IA | $526.20 | $164.03 – $229.64 |
| Covenant Hospital Plainview | Plainview, TX | $527.10 | $166.01 – $180.56 |
| Adventhealth Waterman | Tavares, FL | $527.53 | $177.91 – $358.99 |