In situ hybridization per specimen initial single probe stain cost at US hospitals

HC in Situ Hybridization per Specimen Initial Single Probe Stain · CPT 88365

$21.50

lowest cash price

$338.40

national median

$3,057.35

highest cash price

906

hospitals with a published cash price

Middle half of hospitals (25th–75th percentile) against the full range. The same procedure varies $21.50–$3,057.35 — the variation is the story.

Cheapest published cash price

$21.50

Potomac Valley Hospital — Keyser, WV

Most expensive published cash price

$3,057.35

MEDICAL CITY MCKINNEY HOSPITAL — McKinney, TX

Median cash price over time

Sep 1, 2025 ($353.55) → Sep 1, 2026 ($375.41)

By state

State Hospitals Lowest cash Median Highest
Alaska 5 $143.64 $171.60 $1,567.02
Arizona 23 $65.38 $159.62 $603.56
Arkansas 10 $54.00 $234.65 $627.00
California 86 $22.80 $228.99 $549.85
Colorado 14 $169.59 $1,813.00 $2,404.59
Florida 81 $43.97 $455.16 $2,743.40
Georgia 25 $83.18 $732.42 $1,963.89
Hawaii 2 $160.32 $160.32 $435.00
Illinois 42 $81.25 $476.40 $1,144.50
Indiana 26 $188.50 $902.40 $1,336.80
Iowa 26 $204.10 $471.20 $712.00
Kansas 10 $903.66 $1,152.53 $1,152.53
Kentucky 22 $56.00 $165.70 $1,283.03
Louisiana 2 $136.50 $136.50 $136.50
Maine 7 $105.90 $424.00 $1,100.90
Maryland 2 $243.60 $243.60 $243.60
Michigan 27 $75.20 $364.00 $607.20
Minnesota 18 $340.00 $979.20 $2,344.38
Mississippi 7 $58.74 $72.87 $386.64
Missouri 16 $154.55 $214.50 $1,274.43
Montana 2 $275.20 $275.20 $288.80
Nebraska 13 $126.00 $310.80 $535.50
Nevada 3 $96.35 $106.69 $134.42
New Hampshire 1 $353.55 $353.55 $353.55
New Jersey 21 $47.60 $140.68 $201.80
New Mexico 1 not published by hospital not published by hospital not published by hospital
New York 23 $202.78 $202.78 $1,240.00
North Carolina 14 $139.00 $436.88 $1,846.00
North Dakota 4 $338.40 $338.40 $372.00
Ohio 67 $165.60 $396.75 $752.70
Oklahoma 12 $100.65 $240.83 $432.00
Oregon 12 $107.87 $501.00 $717.40
Pennsylvania 30 $76.20 $337.20 $981.00
South Carolina 11 $241.00 $279.00 $811.00
South Dakota 7 $340.00 $407.20 $483.20
Tennessee 37 $61.80 $134.85 $2,108.96
Texas 116 $103.60 $353.40 $3,057.35
Virginia 41 $132.25 $298.00 $1,785.00
Washington 32 $150.50 $247.00 $716.80
West Virginia 16 $21.50 $263.00 $921.00
Wisconsin 35 $175.43 $322.50 $1,291.51
Wyoming 4 $143.64 $195.05 $274.86

All hospitals

Hospital Location Cash price Negotiated range
CHI Health St. Mary's Nebraska City, NE $528.71 $136.45 – $611.52
CHI Health Plainview Plainview, NE $529.20 $384.30 – $853.15
St. Mary Medical Center Long Beach, CA $529.33 $27.50 – $437.90
HCA FLORIDA SOUTH TAMPA HOSPITAL Tampa, FL $531.87 $149.16 – $284.64
Providence Hood River Memorial Hospital Hood River, OR $532.50 not published
Yavapai Regional Medical Center (East) Prescott, AZ $534.99 $182.64 – $556.75
CHI Health Schuyler Schuyler, NE $535.50 $134.95 – $713.29
SKYLINE MADISON CAMPUS NASHVILLE, TN $536.34 $15.50 – $236.00
St Ritas Medical Center Lima, OH $543.00 not published
STONECREST MEDICAL CENTER Smyrna, TN $543.96 $14.97 – $236.00
AdventHealth Orlando Orlando, FL $549.00 $177.91 – $471.47
Providence Saint John's Health Center Santa Monica, CA $549.85 $62.03 – $405.38
St Mary's Hospital Richmond, VA $552.00 not published
St Francis Medical Center Midlothian, VA $552.00 not published
Memorial Regional Hospital Mechanicsville, VA $552.00 not published
Richmond Community Hospital Richmond, VA $552.00 not published
LEWISGALE HOSPITAL-MONTGOMERY CHRISTIANSBURG, VA $552.00 $149.16 – $637.96
HCA FLORIDA MERCY HOSPITAL MIAMI, FL $552.00 $149.16 – $305.71
Dell Children's Medical Center (Ascension Seton) Austin, TX $557.55 $98.75 – $817.66
NewYork-Presbyterian Queens Flushing, NY $560.00 $20.00 – $212.91
OSF Saint Anthony Medical Center Rockford, IL $560.40 $131.94 – $639.00
CENTRAL PARK ER, A PART OF ROSE DENVER, CO $562.00 $63.68 – $365.44
HCA FLORIDA UNIVERSITY HOSPITAL Davie, FL $562.00 $149.16 – $308.24
WellSpan Chambersburg Hospital Chambersburg, PA $565.60 $14.42 – $788.11
WellSpan Waynesboro Hospital Waynesboro, PA $565.60 $14.28 – $710.65
HSHS St. Anthony's Memorial Hospital Mattoon, IL $565.92 $119.73 – $786.00
HSHS St. John's Hospital IL 62769|301 N. 8th St., IL $566.64 $114.03 – $787.00
Mansfield Hospital Mansfield, OH $568.75 $162.68 – $169.18
Shelby Hospital Shelby, OH $568.75 not published
indian river hospital Vero Beach, FL $573.30 $24.91 – $379.00
OSF Holy Family Medical Center Monmouth, IL $600.80 not published
SSM Health Monroe Hospital Monroe, WI $603.35 $155.48 – $165.49
St. Joseph’s Hospital and Medical Center Phoenix, AZ $603.56 $68.35 – $390.26
OSF St Francis Hospital Escanaba, MI $607.20 not published
Texas Health Center for Diagnostics and Surgery Plano Plano, TX $609.30 $48.21 – $237.05
Texas Health Presbyterian Hospital Flower Mound Flower Mound, TX $609.30 $48.21 – $237.05
Texas Health Presbyterian Hospital Plano Plano, TX $609.30 $48.21 – $237.05
UPMC Wellsboro Wellsboro, PA $619.20 $14.77 – $145.17
CHI St. Vincent Hospital Hot Springs Hot Springs, AR $627.00 $95.46 – $501.60
HCA FLORIDA CAPITAL HOSPITAL TALLAHASSEE, FL $634.00 $149.16 – $268.93
HSHS St. Joseph's Hospital Breese, IL $634.32 $114.03 – $881.00
Grant Memorial Hospital Petersburg, WV $648.00 not published
HSHS St. Francis Hospital LITCHFIELD, IL $650.16 $163.25 – $903.00
Marion General Hospital Marion, OH $653.90 $162.68 – $169.18
Emory Hospital Perry Perry, GA $659.00 $99.96 – $318.81
Emory Hospital Warner Robins Warner Robins, GA $659.00 $99.96 – $323.55
HCA HOUSTON WEST HOUSTON, TX $664.00 $149.16 – $728.49
LAFAYETTE REGIONAL HEALTH CENTER Lexington, MO $665.90 $103.99 – $244.76
Hardin Memorial Hospital Kenton, OH $672.10 not published
Kadlec Regional Medical Center Richland, WA $675.50 $189.85 – $561.09

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