In situ hybridization per specimen initial single probe stain cost at US hospitals
HC in Situ Hybridization per Specimen Initial Single Probe Stain · CPT 88365
$21.50
lowest cash price
$338.40
national median
$3,057.35
highest cash price
906
hospitals with a published cash price
Middle half of hospitals (25th–75th percentile) against the full range. The same procedure varies $21.50–$3,057.35 — the variation is the story.
Median cash price over time
Sep 1, 2025 ($353.55) → Sep 1, 2026 ($375.41)
By state
| State | Hospitals | Lowest cash | Median | Highest |
|---|---|---|---|---|
| Alaska | 5 | $143.64 | $171.60 | $1,567.02 |
| Arizona | 23 | $65.38 | $159.62 | $603.56 |
| Arkansas | 10 | $54.00 | $234.65 | $627.00 |
| California | 86 | $22.80 | $228.99 | $549.85 |
| Colorado | 14 | $169.59 | $1,813.00 | $2,404.59 |
| Florida | 81 | $43.97 | $455.16 | $2,743.40 |
| Georgia | 25 | $83.18 | $732.42 | $1,963.89 |
| Hawaii | 2 | $160.32 | $160.32 | $435.00 |
| Illinois | 42 | $81.25 | $476.40 | $1,144.50 |
| Indiana | 26 | $188.50 | $902.40 | $1,336.80 |
| Iowa | 26 | $204.10 | $471.20 | $712.00 |
| Kansas | 10 | $903.66 | $1,152.53 | $1,152.53 |
| Kentucky | 22 | $56.00 | $165.70 | $1,283.03 |
| Louisiana | 2 | $136.50 | $136.50 | $136.50 |
| Maine | 7 | $105.90 | $424.00 | $1,100.90 |
| Maryland | 2 | $243.60 | $243.60 | $243.60 |
| Michigan | 27 | $75.20 | $364.00 | $607.20 |
| Minnesota | 18 | $340.00 | $979.20 | $2,344.38 |
| Mississippi | 7 | $58.74 | $72.87 | $386.64 |
| Missouri | 16 | $154.55 | $214.50 | $1,274.43 |
| Montana | 2 | $275.20 | $275.20 | $288.80 |
| Nebraska | 13 | $126.00 | $310.80 | $535.50 |
| Nevada | 3 | $96.35 | $106.69 | $134.42 |
| New Hampshire | 1 | $353.55 | $353.55 | $353.55 |
| New Jersey | 21 | $47.60 | $140.68 | $201.80 |
| New Mexico | 1 | not published by hospital | not published by hospital | not published by hospital |
| New York | 23 | $202.78 | $202.78 | $1,240.00 |
| North Carolina | 14 | $139.00 | $436.88 | $1,846.00 |
| North Dakota | 4 | $338.40 | $338.40 | $372.00 |
| Ohio | 67 | $165.60 | $396.75 | $752.70 |
| Oklahoma | 12 | $100.65 | $240.83 | $432.00 |
| Oregon | 12 | $107.87 | $501.00 | $717.40 |
| Pennsylvania | 30 | $76.20 | $337.20 | $981.00 |
| South Carolina | 11 | $241.00 | $279.00 | $811.00 |
| South Dakota | 7 | $340.00 | $407.20 | $483.20 |
| Tennessee | 37 | $61.80 | $134.85 | $2,108.96 |
| Texas | 116 | $103.60 | $353.40 | $3,057.35 |
| Virginia | 41 | $132.25 | $298.00 | $1,785.00 |
| Washington | 32 | $150.50 | $247.00 | $716.80 |
| West Virginia | 16 | $21.50 | $263.00 | $921.00 |
| Wisconsin | 35 | $175.43 | $322.50 | $1,291.51 |
| Wyoming | 4 | $143.64 | $195.05 | $274.86 |
All hospitals
| Hospital | Location | Cash price | Negotiated range |
|---|---|---|---|
| Carolinas Rehabilitation Charlotte | Charlotte, NC | $436.88 | $39.16 – $803.85 |
| Atrium Health University City | Charlotte, NC | $436.88 | $39.16 – $803.85 |
| Atrium Health Carolinas Medical Center | Charlotte, NC | $436.88 | $9.90 – $786.38 |
| cleveland clinic main campus | Cleveland, OH | $437.45 | $1.10 – $605.70 |
| akron general | Akron, OH | $437.45 | $0.95 – $605.70 |
| avon hospital | Avon, OH | $437.45 | $0.95 – $605.70 |
| euclid hospital | Euclid, OH | $437.45 | $0.95 – $605.70 |
| fairview hospital | Cleveland, OH | $437.45 | $0.95 – $605.70 |
| lutheran hospital | Cleveland, OH | $437.45 | $0.95 – $605.70 |
| hillcrest hospital | Mayfield Heights, OH | $437.45 | $0.95 – $605.70 |
| lodi hospital | Lodi, OH | $437.45 | $91.22 – $605.70 |
| marymount hospital | Garfield Heights, OH | $437.45 | $0.95 – $605.70 |
| medina hospital | Medina, OH | $437.45 | $0.95 – $605.70 |
| mercy hospital | Canton, OH | $437.45 | $1.10 – $605.70 |
| south pointe hospital | Warrensville Heights, OH | $437.45 | $0.95 – $605.70 |
| Sanford Luverne Medical Center | Luverne, MN | $442.40 | $133.88 – $497.70 |
| O'Bleness Hospital | Athens, OH | $445.90 | $162.68 – $164.30 |
| Adventhealth Lake Wales | Lake Wales, FL | $455.16 | not published |
| HCA FLORIDA TWIN CITIES HOSPITAL | DEFUNIAK SPRINGS, FL | $456.00 | $149.16 – $292.21 |
| UnityPoint Health - Meriter Hospital | Madison, WI | $459.20 | $39.41 – $90.80 |
| MultiCare Auburn Medical Center | Auburn, WA | $460.00 | $193.88 – $817.83 |
| MultiCare Covington Medical Center | Covington, WA | $460.00 | $193.88 – $817.83 |
| MultiCare Good Samaritan Hospital | Puyallup, WA | $460.00 | $194.86 – $817.83 |
| MultiCare Mary Bridge Children's Hospital | Tacoma, WA | $460.00 | $200.70 – $1,236.77 |
| MultiCare Allenmore Hospital | Tacoma, WA | $460.00 | $194.86 – $817.83 |
| UPMC Presbyterian | Pittsburgh, PA | $463.80 | $13.85 – $181.85 |
| MercyOne Waterloo Medical Center | Waterloo, IA | $467.35 | $156.19 – $510.49 |
| OSF Sacred Heart Medical Center – Urbana | Danville, IL | $470.40 | $182.57 – $186.22 |
| UnityPoint Health - Allen Hospital | Waterloo, IA | $471.20 | $38.95 – $192.44 |
| UnityPoint Health - Finley Hospital | Dubuque, IA | $471.20 | $38.95 – $292.13 |
| UnityPoint Health - Grinnell Regional Medical Center | Grinnell, IA | $471.20 | $38.95 – $170.50 |
| UnityPoint Health - Iowa Lutheran Hospital | Des Moines, IA | $471.20 | $38.95 – $165.10 |
| UnityPoint Health - Jones Regional Medical Center | Anamosa, IA | $471.20 | $38.95 – $323.90 |
| UnityPoint Health - Marshalltown | Marshalltown, IA | $471.20 | $38.95 – $175.28 |
| UnityPoint Health - St. Lukes Downtown | Sioux City, IA | $471.20 | $37.44 – $211.06 |
| UnityPoint Health - Trinity Bettendorf | Bettendorf, IA | $471.20 | $38.95 – $147.46 |
| UnityPoint Health - Trinity Moline | Rock Island, IL | $471.20 | $38.95 – $167.91 |
| UnityPoint Health - Trinity Muscatine | Muscatine, IA | $471.20 | $38.95 – $149.72 |
| UnityPoint Health - Trinity Regional Medical Center | Fort Dodge, IA | $471.20 | $38.95 – $310.39 |
| UnityPoint Health - St. Luke's Hospital | Cedar Rapids, IA | $471.20 | $38.95 – $150.73 |
| MercyOne Genesis Davenport West Medical Center | Davenport, IA | $472.80 | $164.03 – $229.64 |
| CHRISTUS Santa Rosa Emergency Center - Alon | San Antonio, TX | $473.22 | $80.45 – $388.31 |
| OSF St Mary Medical Center | Galesburg, IL | $475.20 | $182.57 – $186.22 |
| OSF Saint Elizabeth Medical Center | Ottawa, IL | $476.40 | $182.57 – $186.22 |
| Berger Hospital | Circleville, OH | $477.75 | $164.27 – $164.27 |
| Providence Medford Medical Center | Medford, OR | $478.50 | $172.66 – $431.65 |
| Sanford Chamberlain Medical Center | Chamberlain, SD | $483.20 | $206.57 – $543.60 |
| Van Wert Hospital | Van Wert, OH | $490.75 | $174.95 – $178.45 |
| University Hospitals Samaritan Medical Center | Ashland, OH | $492.75 | $165.22 – $297.40 |
| HSHS St. Mary's Hospital Medical Center | GREEN BAY, WI | $493.68 | $58.17 – $374.32 |