In situ hybridization per specimen initial single probe stain cost at US hospitals
HC in Situ Hybridization per Specimen Initial Single Probe Stain · CPT 88365
$21.50
lowest cash price
$338.40
national median
$3,057.35
highest cash price
906
hospitals with a published cash price
Middle half of hospitals (25th–75th percentile) against the full range. The same procedure varies $21.50–$3,057.35 — the variation is the story.
Median cash price over time
Sep 1, 2025 ($353.55) → Sep 1, 2026 ($375.41)
By state
| State | Hospitals | Lowest cash | Median | Highest |
|---|---|---|---|---|
| Alaska | 5 | $143.64 | $171.60 | $1,567.02 |
| Arizona | 23 | $65.38 | $159.62 | $603.56 |
| Arkansas | 10 | $54.00 | $234.65 | $627.00 |
| California | 86 | $22.80 | $228.99 | $549.85 |
| Colorado | 14 | $169.59 | $1,813.00 | $2,404.59 |
| Florida | 81 | $43.97 | $455.16 | $2,743.40 |
| Georgia | 25 | $83.18 | $732.42 | $1,963.89 |
| Hawaii | 2 | $160.32 | $160.32 | $435.00 |
| Illinois | 42 | $81.25 | $476.40 | $1,144.50 |
| Indiana | 26 | $188.50 | $902.40 | $1,336.80 |
| Iowa | 26 | $204.10 | $471.20 | $712.00 |
| Kansas | 10 | $903.66 | $1,152.53 | $1,152.53 |
| Kentucky | 22 | $56.00 | $165.70 | $1,283.03 |
| Louisiana | 2 | $136.50 | $136.50 | $136.50 |
| Maine | 7 | $105.90 | $424.00 | $1,100.90 |
| Maryland | 2 | $243.60 | $243.60 | $243.60 |
| Michigan | 27 | $75.20 | $364.00 | $607.20 |
| Minnesota | 18 | $340.00 | $979.20 | $2,344.38 |
| Mississippi | 7 | $58.74 | $72.87 | $386.64 |
| Missouri | 16 | $154.55 | $214.50 | $1,274.43 |
| Montana | 2 | $275.20 | $275.20 | $288.80 |
| Nebraska | 13 | $126.00 | $310.80 | $535.50 |
| Nevada | 3 | $96.35 | $106.69 | $134.42 |
| New Hampshire | 1 | $353.55 | $353.55 | $353.55 |
| New Jersey | 21 | $47.60 | $140.68 | $201.80 |
| New Mexico | 1 | not published by hospital | not published by hospital | not published by hospital |
| New York | 23 | $202.78 | $202.78 | $1,240.00 |
| North Carolina | 14 | $139.00 | $436.88 | $1,846.00 |
| North Dakota | 4 | $338.40 | $338.40 | $372.00 |
| Ohio | 67 | $165.60 | $396.75 | $752.70 |
| Oklahoma | 12 | $100.65 | $240.83 | $432.00 |
| Oregon | 12 | $107.87 | $501.00 | $717.40 |
| Pennsylvania | 30 | $76.20 | $337.20 | $981.00 |
| South Carolina | 11 | $241.00 | $279.00 | $811.00 |
| South Dakota | 7 | $340.00 | $407.20 | $483.20 |
| Tennessee | 37 | $61.80 | $134.85 | $2,108.96 |
| Texas | 116 | $103.60 | $353.40 | $3,057.35 |
| Virginia | 41 | $132.25 | $298.00 | $1,785.00 |
| Washington | 32 | $150.50 | $247.00 | $716.80 |
| West Virginia | 16 | $21.50 | $263.00 | $921.00 |
| Wisconsin | 35 | $175.43 | $322.50 | $1,291.51 |
| Wyoming | 4 | $143.64 | $195.05 | $274.86 |
All hospitals
| Hospital | Location | Cash price | Negotiated range |
|---|---|---|---|
| Methodist Charlton Medical Center | Dallas, TX | $401.50 | $132.55 – $570.96 |
| Methodist Dallas Medical Center | Dallas, TX | $401.50 | $132.55 – $647.64 |
| Methodist Mansfield Medical Center | Mansfield, TX | $401.50 | $132.55 – $596.28 |
| Methodist Midlothian Medical Center | Midlothian, TX | $401.50 | $132.55 – $570.96 |
| Methodist Richardson Medical Center | Richardson, TX | $401.50 | $132.55 – $570.96 |
| Methodist Celina Medical Center | Celina, TX | $401.50 | $143.50 – $427.87 |
| Methodist Southlake Medical Center | Souhtlake, TX | $401.50 | $14.62 – $616.02 |
| Sanford Canton Inwood Medical Center | Canton, SD | $401.60 | $171.68 – $451.80 |
| Queen of The Valley Medical Center | Napa, CA | $402.90 | $99.80 – $287.00 |
| Maryview Hospital | Portsmouth, VA | $405.60 | not published |
| Sanford Clear Lake Medical Center | Clear Lake, SD | $407.20 | $261.12 – $458.10 |
| UPMC Cole | Coudersport, PA | $410.40 | $53.00 – $547.20 |
| Sanford Canby Medical Center | Canby, MN | $412.00 | $124.68 – $463.50 |
| Defiance Hospital | Defiance, OH | $412.20 | not published |
| Covenant Medical Center | Lubbock, TX | $413.70 | $124.66 – $625.66 |
| Covenant Children's Hospital | Lubbock, TX | $413.70 | $310.16 – $625.66 |
| Advocate Illinois Masonic Medical Center | Chicago, IL | $415.00 | $143.50 – $664.00 |
| Advocate Childrens Hospital - Park Ridge | Park Ridge, IL | $415.00 | $143.50 – $664.00 |
| Advocate Sherman Hospital | Elgin, IL | $415.00 | $143.50 – $747.00 |
| Advocate South Suburban Hospital | Hazel Crest, IL | $415.00 | $143.50 – $808.42 |
| Advocate Trinity Hospital | Chicago, IL | $415.00 | $143.50 – $664.00 |
| Advocate Christ Medical Center | Oak Lawn, IL | $415.00 | $143.50 – $664.00 |
| Advocate Condell Medical Center | Libertyville, IL | $415.00 | $143.50 – $664.00 |
| Advocate Good Samaritan Hospital | Downers Grove, IL | $415.00 | $143.50 – $664.00 |
| St. Bernardine Medical Center | San Bernardino, CA | $416.92 | $31.90 – $437.90 |
| NORTHCREST MEDICAL CENTER | SPRINGFIELD, TN | $418.44 | $64.41 – $236.00 |
| Corewell Health Gross Pointe | Grosse Pointe, MI | $419.00 | $54.00 – $258.95 |
| Corewell Health Taylor | Taylor, MI | $419.00 | $54.00 – $274.31 |
| Corewell Health Trenton | Trenton, MI | $419.00 | $54.00 – $261.30 |
| Corewell Health Troy | Troy, MI | $419.00 | $54.00 – $295.13 |
| Corewell Health Wayne | Wayne, MI | $419.00 | $54.00 – $258.35 |
| Chandler Regional Medical Center | Chandler, AZ | $423.44 | $94.79 – $568.72 |
| Pen Bay Medical Center | Rockport, ME | $424.00 | $40.53 – $78.02 |
| Mid Coast Hospital | Brunswick, ME | $424.00 | $24.67 – $299.34 |
| Stephens Memorial Hospital | Norway, ME | $428.40 | $41.90 – $399.27 |
| Sanford USD Medical Center | Sioux Falls, SD | $429.60 | $75.71 – $483.30 |
| Marcum Wallace Hospital | Irvine, KY | $430.20 | not published |
| Sanford Vermillion Hospital | Vermillion, SD | $430.40 | $158.71 – $484.20 |
| MercyOne Centerville Medical Center | Centerville, IA | $431.00 | $117.24 – $431.00 |
| Love County Health Center | Marietta, OK | $432.00 | $150.65 – $150.65 |
| Moanalua Medical Center | HONOLULU, HI | $435.00 | $147.00 – $147.00 |
| Atrium Health Anson | Wadesboro, NC | $436.88 | $39.16 – $830.06 |
| Atrium Health Mercy | Charlotte, NC | $436.88 | $9.90 – $803.85 |
| Atrium Health Pineville | Charlotte, NC | $436.88 | $39.16 – $803.85 |
| Atrium Health Stanly | Albermarle, NC | $436.88 | $39.16 – $838.80 |
| Atrium Health Behavioral Health Charlotte | Charlotte, NC | $436.88 | $39.16 – $768.90 |
| Atrium Health Cleveland | Shelby, NC | $436.88 | $39.16 – $830.06 |
| Atrium Health Cabarrus | Concord, NC | $436.88 | $39.16 – $830.06 |
| Atrium Health Lincoln | Lincolnton, NC | $436.88 | $39.16 – $830.06 |
| Atrium Health Union | Monroe, NC | $436.88 | $39.16 – $830.06 |