In situ hybridization per specimen initial single probe stain cost at US hospitals
HC in Situ Hybridization per Specimen Initial Single Probe Stain · CPT 88365
$21.50
lowest cash price
$338.40
national median
$3,057.35
highest cash price
906
hospitals with a published cash price
Middle half of hospitals (25th–75th percentile) against the full range. The same procedure varies $21.50–$3,057.35 — the variation is the story.
Median cash price over time
Sep 1, 2025 ($353.55) → Sep 1, 2026 ($375.41)
By state
| State | Hospitals | Lowest cash | Median | Highest |
|---|---|---|---|---|
| Alaska | 5 | $143.64 | $171.60 | $1,567.02 |
| Arizona | 23 | $65.38 | $159.62 | $603.56 |
| Arkansas | 10 | $54.00 | $234.65 | $627.00 |
| California | 86 | $22.80 | $228.99 | $549.85 |
| Colorado | 14 | $169.59 | $1,813.00 | $2,404.59 |
| Florida | 81 | $43.97 | $455.16 | $2,743.40 |
| Georgia | 25 | $83.18 | $732.42 | $1,963.89 |
| Hawaii | 2 | $160.32 | $160.32 | $435.00 |
| Illinois | 42 | $81.25 | $476.40 | $1,144.50 |
| Indiana | 26 | $188.50 | $902.40 | $1,336.80 |
| Iowa | 26 | $204.10 | $471.20 | $712.00 |
| Kansas | 10 | $903.66 | $1,152.53 | $1,152.53 |
| Kentucky | 22 | $56.00 | $165.70 | $1,283.03 |
| Louisiana | 2 | $136.50 | $136.50 | $136.50 |
| Maine | 7 | $105.90 | $424.00 | $1,100.90 |
| Maryland | 2 | $243.60 | $243.60 | $243.60 |
| Michigan | 27 | $75.20 | $364.00 | $607.20 |
| Minnesota | 18 | $340.00 | $979.20 | $2,344.38 |
| Mississippi | 7 | $58.74 | $72.87 | $386.64 |
| Missouri | 16 | $154.55 | $214.50 | $1,274.43 |
| Montana | 2 | $275.20 | $275.20 | $288.80 |
| Nebraska | 13 | $126.00 | $310.80 | $535.50 |
| Nevada | 3 | $96.35 | $106.69 | $134.42 |
| New Hampshire | 1 | $353.55 | $353.55 | $353.55 |
| New Jersey | 21 | $47.60 | $140.68 | $201.80 |
| New Mexico | 1 | not published by hospital | not published by hospital | not published by hospital |
| New York | 23 | $202.78 | $202.78 | $1,240.00 |
| North Carolina | 14 | $139.00 | $436.88 | $1,846.00 |
| North Dakota | 4 | $338.40 | $338.40 | $372.00 |
| Ohio | 67 | $165.60 | $396.75 | $752.70 |
| Oklahoma | 12 | $100.65 | $240.83 | $432.00 |
| Oregon | 12 | $107.87 | $501.00 | $717.40 |
| Pennsylvania | 30 | $76.20 | $337.20 | $981.00 |
| South Carolina | 11 | $241.00 | $279.00 | $811.00 |
| South Dakota | 7 | $340.00 | $407.20 | $483.20 |
| Tennessee | 37 | $61.80 | $134.85 | $2,108.96 |
| Texas | 116 | $103.60 | $353.40 | $3,057.35 |
| Virginia | 41 | $132.25 | $298.00 | $1,785.00 |
| Washington | 32 | $150.50 | $247.00 | $716.80 |
| West Virginia | 16 | $21.50 | $263.00 | $921.00 |
| Wisconsin | 35 | $175.43 | $322.50 | $1,291.51 |
| Wyoming | 4 | $143.64 | $195.05 | $274.86 |
All hospitals
| Hospital | Location | Cash price | Negotiated range |
|---|---|---|---|
| CHI Health Midlands | Papillion, NE | $310.80 | $133.20 – $629.00 |
| MUSC Health Main Campus - Charleston | Charleston, SC | $314.00 | $77.39 – $174.30 |
| MUSC Health Orangeburg Medical Center | Orangeburg, SC | $314.00 | $158.46 – $174.30 |
| Ascension NE Wisconsin - St. Elizabeth Campus (Ascension NE Wisconsin, Inc.) | Appleton, WI | $314.07 | $45.42 – $345.95 |
| Ascension Calumet Hospital, Inc. | Chilton, WI | $314.07 | $45.42 – $138.66 |
| Ascension NE Wisconsin - Mercy Campus (Ascension NE Wisconsin, Inc.) | Oshkosh, WI | $314.07 | $45.42 – $345.95 |
| Tiffin Hospital | Tiffin, OH | $315.00 | not published |
| MUSC Health Lancaster Medical Center | Lancaster, SC | $315.50 | $64.93 – $182.11 |
| Urbana Hospital | Urbana, OH | $317.40 | not published |
| ADVENTIST HEALTH MENDOCINO COAST | Fort Bragg, CA | $317.46 | $79.22 – $120.00 |
| Rochester General Hospital | Rochester, NY | $318.32 | $93.99 – $206.29 |
| Newark Wayne Community Hospital | Newark, NY | $318.32 | $93.97 – $206.29 |
| Mary Immaculate Hospital | Newport News, VA | $318.60 | not published |
| SUMMIT MEDICAL CENTER | MT JULIET, TN | $319.00 | $16.57 – $236.00 |
| MEDICAL CITY ARGYLE HOSPITAL | Argyle, TX | $321.85 | $149.16 – $532.78 |
| Aurora Baycare Medical Center | Green Bay, WI | $322.50 | $147.25 – $388.68 |
| Aurora Medical Center Bay Area | Marinette, WI | $322.50 | $147.25 – $388.68 |
| Aurora Medical Center Burlington | Burlington, WI | $322.50 | $147.25 – $388.68 |
| Aurora Medical Center Grafton | Grafton, WI | $322.50 | $147.25 – $388.68 |
| Aurora Medical Center Manitowoc | Two Rivers, WI | $322.50 | $147.25 – $388.68 |
| Aurora Medical Center Kenosha | Kenosha, WI | $322.50 | $147.25 – $388.68 |
| Aurora Medical Center Fond du Lac | Fond Du Lac, WI | $322.50 | $147.25 – $388.68 |
| Aurora Medical Center Sheboygan County | Sheboygan, WI | $322.50 | $147.25 – $388.68 |
| Aurora Sinai Medical Center of Aurora Health Care Metro | Milwaukee, WI | $322.50 | $147.25 – $388.68 |
| Aurora Medical Center Summit | Summit, WI | $322.50 | $147.25 – $388.68 |
| Aurora Medical Center Washington County | Hartford, WI | $322.50 | $147.25 – $388.68 |
| Aurora West Allis Medical Center | West Allis, WI | $322.50 | $147.25 – $388.68 |
| HCA FLORIDA AVENTURA HOSPITAL | HIALEAH, FL | $323.00 | $149.16 – $305.71 |
| Willard Hospital | Willard, OH | $324.60 | not published |
| Orange County Anaheim Medical Center | Anaheim, CA | $326.04 | $193.00 – $193.00 |
| Baldwin Park Medical Center | BALDWIN PARK, CA | $326.04 | $193.00 – $193.00 |
| Downey Medical Center | Downey, CA | $326.04 | $193.00 – $193.00 |
| San Bernardino - Fontana Medical Center | FONTANA, CA | $326.04 | $193.00 – $193.00 |
| Riverside Medical Center | RIVERSIDE, CA | $326.04 | $193.00 – $193.00 |
| South Bay Medical Center | HARBOR CITY, CA | $326.04 | $193.00 – $193.00 |
| San Marcos Medical Center | SAN MARCOS, CA | $326.04 | $193.00 – $193.00 |
| West Los Angeles Medical Center | LOS ANGELES, CA | $326.04 | $193.00 – $193.00 |
| Woodland Hills Medical Center | WOODLAND HILLS, CA | $326.04 | $193.00 – $193.00 |
| Panorama Medical Center | PANORAMA CITY, CA | $326.04 | $193.00 – $193.00 |
| San Diego Clairemont Mesa Medical Center | SAN DIEGO, CA | $326.04 | $193.00 – $193.00 |
| Los Angeles Sunset Medical Center | LOS ANGELES, CA | $326.04 | $193.00 – $193.00 |
| Moreno Valley Medical Center | MORENO VALLEY, CA | $326.04 | $193.00 – $193.00 |
| Banner North Colorado Medical Center - Loveland Campus | Loveland, CO | $331.69 | $167.26 – $746.70 |
| WellSpan Good Samaritan Hospital | Lebanon, PA | $333.60 | $58.13 – $781.20 |
| MercyOne West Des Moines Medical Center | West Des Moines, IA | $335.00 | $67.34 – $335.00 |
| UPMC Community Osteopathic | Harrisburg, PA | $337.20 | $15.12 – $477.70 |
| UPMC Hanover | Hanover, PA | $337.20 | $15.12 – $261.92 |
| UPMC Lititz | Lititz, PA | $337.20 | $15.12 – $263.33 |
| UPMC Memorial | York, PA | $337.20 | $15.12 – $445.22 |
| UPMC Somerset | Somerset, PA | $337.20 | $13.27 – $163.37 |