In situ hybridization per specimen initial single probe stain cost at US hospitals
HC in Situ Hybridization per Specimen Initial Single Probe Stain · CPT 88365
$21.50
lowest cash price
$338.40
national median
$3,057.35
highest cash price
906
hospitals with a published cash price
Middle half of hospitals (25th–75th percentile) against the full range. The same procedure varies $21.50–$3,057.35 — the variation is the story.
Median cash price over time
Sep 1, 2025 ($353.55) → Sep 1, 2026 ($375.41)
By state
| State | Hospitals | Lowest cash | Median | Highest |
|---|---|---|---|---|
| Alaska | 5 | $143.64 | $171.60 | $1,567.02 |
| Arizona | 23 | $65.38 | $159.62 | $603.56 |
| Arkansas | 10 | $54.00 | $234.65 | $627.00 |
| California | 86 | $22.80 | $228.99 | $549.85 |
| Colorado | 14 | $169.59 | $1,813.00 | $2,404.59 |
| Florida | 81 | $43.97 | $455.16 | $2,743.40 |
| Georgia | 25 | $83.18 | $732.42 | $1,963.89 |
| Hawaii | 2 | $160.32 | $160.32 | $435.00 |
| Illinois | 42 | $81.25 | $476.40 | $1,144.50 |
| Indiana | 26 | $188.50 | $902.40 | $1,336.80 |
| Iowa | 26 | $204.10 | $471.20 | $712.00 |
| Kansas | 10 | $903.66 | $1,152.53 | $1,152.53 |
| Kentucky | 22 | $56.00 | $165.70 | $1,283.03 |
| Louisiana | 2 | $136.50 | $136.50 | $136.50 |
| Maine | 7 | $105.90 | $424.00 | $1,100.90 |
| Maryland | 2 | $243.60 | $243.60 | $243.60 |
| Michigan | 27 | $75.20 | $364.00 | $607.20 |
| Minnesota | 18 | $340.00 | $979.20 | $2,344.38 |
| Mississippi | 7 | $58.74 | $72.87 | $386.64 |
| Missouri | 16 | $154.55 | $214.50 | $1,274.43 |
| Montana | 2 | $275.20 | $275.20 | $288.80 |
| Nebraska | 13 | $126.00 | $310.80 | $535.50 |
| Nevada | 3 | $96.35 | $106.69 | $134.42 |
| New Hampshire | 1 | $353.55 | $353.55 | $353.55 |
| New Jersey | 21 | $47.60 | $140.68 | $201.80 |
| New Mexico | 1 | not published by hospital | not published by hospital | not published by hospital |
| New York | 23 | $202.78 | $202.78 | $1,240.00 |
| North Carolina | 14 | $139.00 | $436.88 | $1,846.00 |
| North Dakota | 4 | $338.40 | $338.40 | $372.00 |
| Ohio | 67 | $165.60 | $396.75 | $752.70 |
| Oklahoma | 12 | $100.65 | $240.83 | $432.00 |
| Oregon | 12 | $107.87 | $501.00 | $717.40 |
| Pennsylvania | 30 | $76.20 | $337.20 | $981.00 |
| South Carolina | 11 | $241.00 | $279.00 | $811.00 |
| South Dakota | 7 | $340.00 | $407.20 | $483.20 |
| Tennessee | 37 | $61.80 | $134.85 | $2,108.96 |
| Texas | 116 | $103.60 | $353.40 | $3,057.35 |
| Virginia | 41 | $132.25 | $298.00 | $1,785.00 |
| Washington | 32 | $150.50 | $247.00 | $716.80 |
| West Virginia | 16 | $21.50 | $263.00 | $921.00 |
| Wisconsin | 35 | $175.43 | $322.50 | $1,291.51 |
| Wyoming | 4 | $143.64 | $195.05 | $274.86 |
All hospitals
| Hospital | Location | Cash price | Negotiated range |
|---|---|---|---|
| Dell Seton Medical Center at The University of Texas (Ascension Seton) | Austin, TX | $286.74 | $98.75 – $817.66 |
| Ascension Seton Medical Center Austin (Ascension Seton) | Austin, TX | $286.74 | $98.75 – $817.66 |
| Providence St Joseph Medical Center | Polson, MT | $288.80 | $513.12 – $513.12 |
| Mercy Hospital Lincoln | Troy, MO | $289.25 | $101.78 – $224.98 |
| SSM Health Saint Louis University Hospital | Saint Louis, MO | $289.30 | $128.83 – $236.08 |
| Gouverneur Hospital | Gouverneur, NY | $290.37 | $179.38 – $179.38 |
| St. Luke's Health - The Vintage Hospital | Houston, TX | $291.90 | $193.77 – $834.00 |
| Baylor St Luke's Medical Center | Houston, TX | $291.90 | $138.52 – $834.00 |
| St. Luke's Health - Sugar Land Hospital | Sugar Land, TX | $291.90 | $193.77 – $834.00 |
| St. Luke's Health - Springwoods Village Hospital | Spring, TX | $291.90 | $193.77 – $834.00 |
| St. Luke's Health - Lakeside Hospital | The Woodlands, TX | $291.90 | $193.77 – $834.00 |
| Massena Hospital | Massena, NY | $291.90 | $269.07 – $269.07 |
| Adventhealth Palm Coast | Palm Coast, FL | $292.67 | $169.02 – $380.01 |
| Adventhealth Palm Coast Parkway | Palm Coast, FL | $292.67 | $169.02 – $380.01 |
| Kettering Health Main Campus (Kettering) | Kettering, OH | $294.40 | $42.27 – $450.99 |
| Kettering Health Miamisburg (Sycamore) | Miamisburg, OH | $294.40 | $42.27 – $453.80 |
| Kettering Health Dayton (Grandview) | Dayton, OH | $294.40 | $42.27 – $450.99 |
| Soin Medical Center | Beaver Creek, OH | $294.40 | $42.27 – $450.99 |
| Kettering Health Greene Memorial | Xenia, OH | $294.40 | $42.27 – $448.58 |
| Kettering Health Hamilton (Fort Hamilton) | Hamilton, OH | $294.40 | $42.27 – $453.80 |
| Kettering Health Troy | Troy, OH | $294.40 | $42.27 – $448.58 |
| UPMC Hamot | Erie, PA | $295.20 | $26.23 – $213.04 |
| BAYLOR SCOTT & WHITE MEDICAL CENTER - BUDA | Suite 110, TX | $296.45 | $36.00 – $423.12 |
| BAYLOR SCOTT & WHITE MEDICAL CENTER - PFLUGERVILLE | Suite 100, TX | $296.45 | $36.00 – $741.89 |
| BAYLOR SCOTT & WHITE EMERGENCY MEDICAL CENTER - CEDAR PARK | Cedar Park, TX | $296.45 | $36.00 – $444.67 |
| BAYLOR SCOTT & WHITE MEDICAL CENTER - TAYLOR | Taylor, TX | $296.45 | $36.00 – $423.12 |
| Inova Alexandria Hospital | Alexandria, VA | $298.00 | $152.32 – $374.94 |
| Inova Fairfax Hospital | Falls Church, VA | $298.00 | $152.32 – $374.94 |
| Inova Fair Oaks Hospital | VA 22033-1709, VA | $298.00 | $152.32 – $374.94 |
| Inova Loudoun Hospital | Leesburg, VA | $298.00 | $152.32 – $374.94 |
| Inova Mount Vernon Hospital | Alexandria, VA | $298.00 | $152.32 – $374.94 |
| Providence Sacred Heart Medical Center and Children's Hospital | Spokane, WA | $298.20 | $189.85 – $516.60 |
| UPMC Mercy | Pittsburgh, PA | $300.00 | $18.14 – $179.71 |
| CHI Health Mercy Corning | Corning, IA | $302.40 | $270.90 – $617.40 |
| Adventhealth Fish Memorial | Orange City, FL | $302.52 | $169.02 – $338.61 |
| OSF Healthcare Divine Mercy Continuing Care Hospital | Peoria, IL | $303.60 | not published |
| University Hospitals Conneaut Medical Center | Conneaut, OH | $303.75 | $59.00 – $297.15 |
| University Hospitals Geneva Medical Center | Geneva, OH | $303.75 | $69.00 – $297.15 |
| Mercy Hospital Kingfisher | Kingfisher, OK | $304.20 | $150.65 – $304.61 |
| Adventhealth Manchester | Manchester, KY | $306.87 | $64.41 – $159.86 |
| Petaluma Valley Hospital | Petaluma, CA | $307.53 | $78.97 – $287.00 |
| Ascension Columbia St. Mary's Hospital - Ozaukee Campus (Columbia St. Mary's Hospital Milwaukee, Inc.) | Mequon, WI | $307.93 | $58.50 – $367.00 |
| Ascension Columbia St. Mary's Hospital - Milwaukee Campus (Columbia St. Mary's Hospital Milwaukee, Inc.) | Milwaukee, WI | $307.93 | $58.50 – $367.00 |
| Providence St Joseph Hospital | Chewelah, WA | $308.70 | not published |
| CHI Health Missouri Valley | Missouri Valley, IA | $308.70 | $220.50 – $617.40 |
| CHI Health Mercy Council Bluffs | Council Bluffs, IA | $310.80 | $111.00 – $629.00 |
| CHI Health Creighton University Medical Center - Bergan Mercy | Omaha, NE | $310.80 | $125.80 – $629.00 |
| Lasting Hope Recovery Center | Omaha, NE | $310.80 | $125.80 – $629.00 |
| CHI Health Lakeside | Omaha, NE | $310.80 | $118.40 – $629.00 |
| CHI Health Immanuel | Omaha, NE | $310.80 | $103.60 – $629.00 |