In situ hybridization per specimen initial single probe stain cost at US hospitals
HC in Situ Hybridization per Specimen Initial Single Probe Stain · CPT 88365
$21.50
lowest cash price
$338.40
national median
$3,057.35
highest cash price
906
hospitals with a published cash price
Middle half of hospitals (25th–75th percentile) against the full range. The same procedure varies $21.50–$3,057.35 — the variation is the story.
Median cash price over time
Sep 1, 2025 ($353.55) → Sep 1, 2026 ($375.41)
By state
| State | Hospitals | Lowest cash | Median | Highest |
|---|---|---|---|---|
| Alaska | 5 | $143.64 | $171.60 | $1,567.02 |
| Arizona | 23 | $65.38 | $159.62 | $603.56 |
| Arkansas | 10 | $54.00 | $234.65 | $627.00 |
| California | 86 | $22.80 | $228.99 | $549.85 |
| Colorado | 14 | $169.59 | $1,813.00 | $2,404.59 |
| Florida | 81 | $43.97 | $455.16 | $2,743.40 |
| Georgia | 25 | $83.18 | $732.42 | $1,963.89 |
| Hawaii | 2 | $160.32 | $160.32 | $435.00 |
| Illinois | 42 | $81.25 | $476.40 | $1,144.50 |
| Indiana | 26 | $188.50 | $902.40 | $1,336.80 |
| Iowa | 26 | $204.10 | $471.20 | $712.00 |
| Kansas | 10 | $903.66 | $1,152.53 | $1,152.53 |
| Kentucky | 22 | $56.00 | $165.70 | $1,283.03 |
| Louisiana | 2 | $136.50 | $136.50 | $136.50 |
| Maine | 7 | $105.90 | $424.00 | $1,100.90 |
| Maryland | 2 | $243.60 | $243.60 | $243.60 |
| Michigan | 27 | $75.20 | $364.00 | $607.20 |
| Minnesota | 18 | $340.00 | $979.20 | $2,344.38 |
| Mississippi | 7 | $58.74 | $72.87 | $386.64 |
| Missouri | 16 | $154.55 | $214.50 | $1,274.43 |
| Montana | 2 | $275.20 | $275.20 | $288.80 |
| Nebraska | 13 | $126.00 | $310.80 | $535.50 |
| Nevada | 3 | $96.35 | $106.69 | $134.42 |
| New Hampshire | 1 | $353.55 | $353.55 | $353.55 |
| New Jersey | 21 | $47.60 | $140.68 | $201.80 |
| New Mexico | 1 | not published by hospital | not published by hospital | not published by hospital |
| New York | 23 | $202.78 | $202.78 | $1,240.00 |
| North Carolina | 14 | $139.00 | $436.88 | $1,846.00 |
| North Dakota | 4 | $338.40 | $338.40 | $372.00 |
| Ohio | 67 | $165.60 | $396.75 | $752.70 |
| Oklahoma | 12 | $100.65 | $240.83 | $432.00 |
| Oregon | 12 | $107.87 | $501.00 | $717.40 |
| Pennsylvania | 30 | $76.20 | $337.20 | $981.00 |
| South Carolina | 11 | $241.00 | $279.00 | $811.00 |
| South Dakota | 7 | $340.00 | $407.20 | $483.20 |
| Tennessee | 37 | $61.80 | $134.85 | $2,108.96 |
| Texas | 116 | $103.60 | $353.40 | $3,057.35 |
| Virginia | 41 | $132.25 | $298.00 | $1,785.00 |
| Washington | 32 | $150.50 | $247.00 | $716.80 |
| West Virginia | 16 | $21.50 | $263.00 | $921.00 |
| Wisconsin | 35 | $175.43 | $322.50 | $1,291.51 |
| Wyoming | 4 | $143.64 | $195.05 | $274.86 |
All hospitals
| Hospital | Location | Cash price | Negotiated range |
|---|---|---|---|
| UPMC Carlisle | Carlisle, PA | $337.20 | $15.12 – $477.70 |
| Sanford Medical Center Hillsboro | Hillsboro, ND | $338.40 | $102.41 – $380.70 |
| Sanford Medical Center Mayville | Mayville, ND | $338.40 | $102.41 – $380.70 |
| Sanford Bemidji Medical Center | Bemidji, MN | $340.00 | $123.23 – $382.50 |
| Sanford Fargo Medical Center | Fargo, ND | $340.00 | $124.46 – $382.50 |
| Sanford Aberdeen Medical Center | Aberdeen, SD | $340.00 | $162.79 – $382.50 |
| Houston Methodist Hospital | Houston, TX | $340.00 | $124.08 – $684.58 |
| Houston Methodist Sugar Land Hospital | Sugar Land, TX | $340.00 | $124.08 – $333.74 |
| Houston Methodist West Hospital | Houston, TX | $340.00 | $124.08 – $684.58 |
| Houston Methodist Baytown Hospital | Baytown, TX | $340.00 | $124.08 – $333.74 |
| Houston Methodist Willowbrook Hospital | Houston, TX | $340.00 | $124.08 – $333.74 |
| Houston Methodist Clear Lake Hospital | Nassau Bay, TX | $340.00 | $124.08 – $333.74 |
| Houston Methodist The Woodlands Hospital | The Woodlands, TX | $340.00 | $124.08 – $342.29 |
| Houston Methodist Continuing Care Hospital | Katy, TX | $340.00 | not published |
| Houston Methodist Cypress Hospital | Cypress, TX | $340.00 | $124.08 – $333.74 |
| Providence Holy Family Hospital | Spokane, WA | $341.60 | $189.85 – $722.40 |
| Sanford Wheaton | Wheaton, MN | $341.60 | $103.38 – $384.30 |
| Morrow County Hospital | Mount Gilead, OH | $341.90 | $84.17 – $138.87 |
| Providence St Joseph Hospital Orange | Orange, CA | $342.72 | $117.09 – $405.38 |
| Canton-Potsdam Hospital | Potsdam, NY | $344.29 | $109.80 – $128.10 |
| Weirton Medical Center | Weirton, WV | $345.00 | $11.54 – $827.69 |
| MEDICAL CITY NORTH HILLS HOSPITAL | North Richland Hills, TX | $348.33 | $149.16 – $532.78 |
| Mercy Hospital Carthage | Carthage, MO | $350.35 | $52.02 – $443.21 |
| Sanford Hospital Webster | Webster, SD | $352.80 | $138.47 – $396.90 |
| BAYLOR SCOTT & WHITE MEDICAL CENTER - BRENHAM | Brenham, TX | $352.98 | $36.00 – $529.47 |
| BAYLOR SCOTT & WHITE MEDICAL CENTER - COLLEGE STATION | College Station, TX | $352.98 | $36.00 – $529.47 |
| BAYLOR SCOTT & WHITE CONTINUING CARE HOSPITAL | Temple, TX | $352.98 | $26.00 – $529.47 |
| BAYLOR SCOTT & WHITE MEDICAL CENTER HILLCREST | Waco, TX | $352.98 | $70.60 – $441.23 |
| BAYLOR SCOTT & WHITE MCLANE CHILDREN'S MEDICAL CENTER | Temple, TX | $352.98 | $36.00 – $529.47 |
| Parkview Montpelier Hospital | Montpelier, OH | $353.00 | not published |
| Parkview Bryan Hospital | Bryan, OH | $353.00 | $169.50 – $508.49 |
| Texas Health Harris Methodist Hospital Alliance | Fort Worth, TX | $353.40 | $48.21 – $237.05 |
| Texas Health Arlington Memorial Hospital | Arlington, TX | $353.40 | $48.21 – $237.05 |
| Texas Health Presbyterian Hospital Allen | Allen, TX | $353.40 | $48.21 – $237.05 |
| Texas Health Harris Methodist Hospital Azle | Azle, TX | $353.40 | $48.21 – $237.05 |
| Texas Health Presbyterian Hospital Denton | Denton, TX | $353.40 | $48.21 – $237.05 |
| Texas Health Presbyterian Hospital Dallas | Dallas, TX | $353.40 | $48.21 – $237.05 |
| Texas Health Hospital Frisco | Frisco, TX | $353.40 | $48.21 – $237.05 |
| Texas Health Heart & Vascular Hospital Arlington | Arlington, TX | $353.40 | $48.21 – $237.05 |
| Texas Health Presbyterian Hospital Kaufman | Kaufman, TX | $353.40 | $48.21 – $237.05 |
| Texas Health Harris Methodist Hospital Hurst-Euless-Bedford | Bedford, TX | $353.40 | $48.21 – $237.05 |
| Texas Health Harris Methodist Hospital Southlake | Southlake, TX | $353.40 | $48.21 – $237.05 |
| Texas Health Harris Methodist Hospital Southwest Fort Worth | Fort Worth, TX | $353.40 | $48.21 – $237.05 |
| Texas Health Harris Methodist Hospital Fort Worth | Fort Worth, TX | $353.40 | $48.21 – $237.05 |
| Texas Health Harris Methodist Hospital Stephenville | Stephenville, TX | $353.40 | $48.21 – $237.05 |
| Texas Health Harris Methodist Hospital Cleburne | Cleburne, TX | $353.40 | $48.21 – $237.05 |
| MaineHealth - Memorial Hospital | North Conway, NH | $353.55 | $40.13 – $150.59 |
| HCA FLORIDA JFK HOSPITAL | PALM BEACH GARDENS, FL | $356.00 | $149.16 – $294.39 |
| St Anne Hospital | Toledo, OH | $358.20 | not published |
| HCA FLORIDA WESTSIDE HOSPITAL | PLANTATION, FL | $363.00 | $149.16 – $308.24 |