In situ hybridization per specimen initial single probe stain cost at US hospitals
HC in Situ Hybridization per Specimen Initial Single Probe Stain · CPT 88365
$21.50
lowest cash price
$338.40
national median
$3,057.35
highest cash price
906
hospitals with a published cash price
Middle half of hospitals (25th–75th percentile) against the full range. The same procedure varies $21.50–$3,057.35 — the variation is the story.
Median cash price over time
Sep 1, 2025 ($353.55) → Sep 1, 2026 ($375.41)
By state
| State | Hospitals | Lowest cash | Median | Highest |
|---|---|---|---|---|
| Alaska | 5 | $143.64 | $171.60 | $1,567.02 |
| Arizona | 23 | $65.38 | $159.62 | $603.56 |
| Arkansas | 10 | $54.00 | $234.65 | $627.00 |
| California | 86 | $22.80 | $228.99 | $549.85 |
| Colorado | 14 | $169.59 | $1,813.00 | $2,404.59 |
| Florida | 81 | $43.97 | $455.16 | $2,743.40 |
| Georgia | 25 | $83.18 | $732.42 | $1,963.89 |
| Hawaii | 2 | $160.32 | $160.32 | $435.00 |
| Illinois | 42 | $81.25 | $476.40 | $1,144.50 |
| Indiana | 26 | $188.50 | $902.40 | $1,336.80 |
| Iowa | 26 | $204.10 | $471.20 | $712.00 |
| Kansas | 10 | $903.66 | $1,152.53 | $1,152.53 |
| Kentucky | 22 | $56.00 | $165.70 | $1,283.03 |
| Louisiana | 2 | $136.50 | $136.50 | $136.50 |
| Maine | 7 | $105.90 | $424.00 | $1,100.90 |
| Maryland | 2 | $243.60 | $243.60 | $243.60 |
| Michigan | 27 | $75.20 | $364.00 | $607.20 |
| Minnesota | 18 | $340.00 | $979.20 | $2,344.38 |
| Mississippi | 7 | $58.74 | $72.87 | $386.64 |
| Missouri | 16 | $154.55 | $214.50 | $1,274.43 |
| Montana | 2 | $275.20 | $275.20 | $288.80 |
| Nebraska | 13 | $126.00 | $310.80 | $535.50 |
| Nevada | 3 | $96.35 | $106.69 | $134.42 |
| New Hampshire | 1 | $353.55 | $353.55 | $353.55 |
| New Jersey | 21 | $47.60 | $140.68 | $201.80 |
| New Mexico | 1 | not published by hospital | not published by hospital | not published by hospital |
| New York | 23 | $202.78 | $202.78 | $1,240.00 |
| North Carolina | 14 | $139.00 | $436.88 | $1,846.00 |
| North Dakota | 4 | $338.40 | $338.40 | $372.00 |
| Ohio | 67 | $165.60 | $396.75 | $752.70 |
| Oklahoma | 12 | $100.65 | $240.83 | $432.00 |
| Oregon | 12 | $107.87 | $501.00 | $717.40 |
| Pennsylvania | 30 | $76.20 | $337.20 | $981.00 |
| South Carolina | 11 | $241.00 | $279.00 | $811.00 |
| South Dakota | 7 | $340.00 | $407.20 | $483.20 |
| Tennessee | 37 | $61.80 | $134.85 | $2,108.96 |
| Texas | 116 | $103.60 | $353.40 | $3,057.35 |
| Virginia | 41 | $132.25 | $298.00 | $1,785.00 |
| Washington | 32 | $150.50 | $247.00 | $716.80 |
| West Virginia | 16 | $21.50 | $263.00 | $921.00 |
| Wisconsin | 35 | $175.43 | $322.50 | $1,291.51 |
| Wyoming | 4 | $143.64 | $195.05 | $274.86 |
All hospitals
| Hospital | Location | Cash price | Negotiated range |
|---|---|---|---|
| UPMC Western Maryland | Cumberland, MD | $243.60 | $406.00 – $406.00 |
| MultiCare Capital Medical Center | Olympia, WA | $243.60 | $193.34 – $881.47 |
| Mercy Hospital Ozark | River Ozark, AR | $245.05 | $53.26 – $339.02 |
| Mercy Hospital Paris | Academy Paris, AR | $245.05 | $53.26 – $339.02 |
| Mercy Hospital Waldron | Waldron, AR | $245.05 | $53.26 – $339.02 |
| Virginia Mason Medical Center | Seattle, WA | $246.84 | $465.77 – $465.77 |
| Providence Regional Medical Center Everett - Colby Campus | Everett, WA | $247.00 | $194.02 – $602.70 |
| Ascension Seton Edgar B. Davis (Ascension Seton) | Luling, TX | $248.58 | $98.75 – $817.66 |
| Ascension Seton Highland Lakes (Ascension Seton) | Burnet, TX | $248.58 | $98.75 – $817.66 |
| Lorain Hospital | Lorain, OH | $250.80 | not published |
| Ascension Saint Thomas Highlands | Sparta, TN | $251.55 | $10.69 – $429.57 |
| Ascension Saint Thomas River Park | McMinnville, TN | $251.55 | $15.97 – $429.57 |
| Ascension Saint Thomas Rutherford | Murfreesboro, TN | $251.55 | $10.69 – $429.57 |
| Ascension Saint Thomas Midtown | Nashville, TN | $251.55 | $10.69 – $429.57 |
| MUSC Health Black River Medical Center | Cades, SC | $254.00 | $15.34 – $174.30 |
| Ascension Seton Cedar Park Hospital | Cedar Park, TX | $254.19 | $98.75 – $817.66 |
| MUSC Health Chester Medical Center | Chester, SC | $256.50 | $42.92 – $181.15 |
| Covenant Specialty Hospital | Lubbock, TX | $257.04 | not published |
| Mercy Hospital Boonville | Booneville, AR | $260.65 | $53.26 – $339.02 |
| Swedish Edmonds Hospital | Edmonds, WA | $261.12 | $194.02 – $645.75 |
| MultiCare Valley Hospital | Spokane Valley, WA | $261.60 | $191.64 – $699.76 |
| MultiCare Deaconess Hospital | Spokane, WA | $261.60 | $186.05 – $701.34 |
| United Hospital Center | Bridgeport, WV | $263.00 | $175.64 – $277.51 |
| Berkeley Medical Center | Martinsburg, WV | $263.00 | $12.35 – $259.07 |
| Camden Clark Medical Center | Parkersburg, WV | $263.00 | $162.63 – $256.96 |
| Reynolds Memorial Hospital | Glen Dale, WV | $263.00 | $12.12 – $256.96 |
| Wetzel County Hospital | New Martinsville, WV | $263.00 | $12.69 – $275.19 |
| Parkwest Medical Center | Knoxville, TN | $263.34 | $48.44 – $549.51 |
| Ascension Saint Thomas DeKalb | Smithville, TN | $264.15 | $10.69 – $429.57 |
| St Francis Eastside | Greenville, SC | $265.80 | not published |
| Trinity Medical Center East | Steubenville, OH | $268.30 | $54.86 – $416.57 |
| Platte County Hospital | Wheatland, WY | $274.86 | $165.12 – $333.68 |
| St Patrick Hospital - Broadway Campus | Missoula, MT | $275.20 | $175.80 – $513.12 |
| UPMC Williamsport | Williamsport, PA | $275.40 | $14.77 – $176.48 |
| UPMC Altoona | Altoona, PA | $275.40 | $26.23 – $367.20 |
| Santa Rosa Memorial Hospital | Santa Rosa, CA | $277.44 | $84.91 – $287.00 |
| St Francis Downtown | Greenville, SC | $279.00 | not published |
| MercyOne Dyersville Medical Center | Dyersville, IA | $280.15 | $156.19 – $485.13 |
| MercyOne Elkader Medical Center | Elkader, IA | $280.15 | $156.19 – $450.48 |
| MercyOne Newton Medical Center | Newton, IA | $280.15 | $156.19 – $431.00 |
| MEDICAL CITY FORT WORTH HOSPITAL | FT WORTH, TX | $280.75 | $149.16 – $553.90 |
| Mercy Hospital Healdton | Healdton, OK | $280.80 | $150.65 – $304.61 |
| Providence Mission Hospital - Mission Viejo | Mission Viejo, CA | $282.72 | $126.73 – $405.38 |
| Providence Centralia Hospital | Centralia, WA | $282.88 | $197.29 – $894.01 |
| Providence St Peter Hospital | Olympia, WA | $282.88 | $166.55 – $803.60 |
| Uniontown Hospital | Uniontown, PA | $283.50 | $12.69 – $384.78 |
| Southern Virginia Medical Center | Emporia, VA | $285.60 | not published |
| Southside Regional Medical Center | Petersburg, VA | $285.60 | not published |
| Ascension Seton Northwest (Ascension Seton) | Austin, TX | $286.74 | $98.75 – $817.66 |
| Ascension Seton Smithville (Ascension Seton) | Smithville, TX | $286.74 | $98.75 – $817.66 |