In situ hybridization per specimen initial single probe stain cost at US hospitals
HC in Situ Hybridization per Specimen Initial Single Probe Stain · CPT 88365
$21.50
lowest cash price
$338.40
national median
$3,057.35
highest cash price
906
hospitals with a published cash price
Middle half of hospitals (25th–75th percentile) against the full range. The same procedure varies $21.50–$3,057.35 — the variation is the story.
Median cash price over time
Sep 1, 2025 ($353.55) → Sep 1, 2026 ($375.41)
By state
| State | Hospitals | Lowest cash | Median | Highest |
|---|---|---|---|---|
| Alaska | 5 | $143.64 | $171.60 | $1,567.02 |
| Arizona | 23 | $65.38 | $159.62 | $603.56 |
| Arkansas | 10 | $54.00 | $234.65 | $627.00 |
| California | 86 | $22.80 | $228.99 | $549.85 |
| Colorado | 14 | $169.59 | $1,813.00 | $2,404.59 |
| Florida | 81 | $43.97 | $455.16 | $2,743.40 |
| Georgia | 25 | $83.18 | $732.42 | $1,963.89 |
| Hawaii | 2 | $160.32 | $160.32 | $435.00 |
| Illinois | 42 | $81.25 | $476.40 | $1,144.50 |
| Indiana | 26 | $188.50 | $902.40 | $1,336.80 |
| Iowa | 26 | $204.10 | $471.20 | $712.00 |
| Kansas | 10 | $903.66 | $1,152.53 | $1,152.53 |
| Kentucky | 22 | $56.00 | $165.70 | $1,283.03 |
| Louisiana | 2 | $136.50 | $136.50 | $136.50 |
| Maine | 7 | $105.90 | $424.00 | $1,100.90 |
| Maryland | 2 | $243.60 | $243.60 | $243.60 |
| Michigan | 27 | $75.20 | $364.00 | $607.20 |
| Minnesota | 18 | $340.00 | $979.20 | $2,344.38 |
| Mississippi | 7 | $58.74 | $72.87 | $386.64 |
| Missouri | 16 | $154.55 | $214.50 | $1,274.43 |
| Montana | 2 | $275.20 | $275.20 | $288.80 |
| Nebraska | 13 | $126.00 | $310.80 | $535.50 |
| Nevada | 3 | $96.35 | $106.69 | $134.42 |
| New Hampshire | 1 | $353.55 | $353.55 | $353.55 |
| New Jersey | 21 | $47.60 | $140.68 | $201.80 |
| New Mexico | 1 | not published by hospital | not published by hospital | not published by hospital |
| New York | 23 | $202.78 | $202.78 | $1,240.00 |
| North Carolina | 14 | $139.00 | $436.88 | $1,846.00 |
| North Dakota | 4 | $338.40 | $338.40 | $372.00 |
| Ohio | 67 | $165.60 | $396.75 | $752.70 |
| Oklahoma | 12 | $100.65 | $240.83 | $432.00 |
| Oregon | 12 | $107.87 | $501.00 | $717.40 |
| Pennsylvania | 30 | $76.20 | $337.20 | $981.00 |
| South Carolina | 11 | $241.00 | $279.00 | $811.00 |
| South Dakota | 7 | $340.00 | $407.20 | $483.20 |
| Tennessee | 37 | $61.80 | $134.85 | $2,108.96 |
| Texas | 116 | $103.60 | $353.40 | $3,057.35 |
| Virginia | 41 | $132.25 | $298.00 | $1,785.00 |
| Washington | 32 | $150.50 | $247.00 | $716.80 |
| West Virginia | 16 | $21.50 | $263.00 | $921.00 |
| Wisconsin | 35 | $175.43 | $322.50 | $1,291.51 |
| Wyoming | 4 | $143.64 | $195.05 | $274.86 |
All hospitals
| Hospital | Location | Cash price | Negotiated range |
|---|---|---|---|
| Providence Valdez Medical Center | Valdez, AK | $210.60 | not published |
| St. Luke's Health Memorial Lufkin | Lufkin, TX | $211.65 | $272.65 – $1,269.90 |
| St. Luke's Health Memorial Livingston | Livingston, TX | $211.65 | $272.65 – $1,269.90 |
| St. Luke's Health Memorial San Augustine | San Augustine, TX | $211.65 | $253.98 – $1,467.44 |
| UPMC Chautauqua | Jamestown, NY | $211.80 | $41.16 – $525.08 |
| East Morgan County Hospital | Brush, CO | $211.90 | $144.96 – $333.68 |
| Sentara Martha Jefferson Hospital | Charlottesville, VA | $213.50 | $41.78 – $174.54 |
| Sentara RMH Medical Center | Harrisonburg, VA | $213.50 | $135.40 – $174.54 |
| SSM Health St. Mary's Hospital - Jefferson City | Jefferson City, MO | $214.50 | $134.24 – $307.16 |
| Redwood Memorial Hospital | Fortuna, CA | $215.22 | $113.44 – $113.44 |
| Ogallala Community Hospital | Ogallala, NE | $215.69 | $151.36 – $333.68 |
| Banner Page Hospital | Page, AZ | $217.17 | $108.14 – $346.75 |
| HCA FLORIDA POINCIANA HOSPITAL | DAVENPORT, FL | $220.65 | $149.16 – $289.52 |
| Swedish Medical Center Cherry Hill | Seattle, WA | $228.00 | $197.29 – $652.93 |
| Swedish Medical Center - First Hill Campus | Seattle, WA | $228.00 | $197.29 – $674.45 |
| Swedish Issaquah | Issaquah, WA | $228.00 | $197.84 – $674.45 |
| Providence St Joseph Hospital Eureka | Eureka, CA | $228.99 | $113.18 – $287.00 |
| Parkview Huntington Hospital | Huntington, IN | $229.50 | $180.25 – $246.11 |
| Parkview Whitley Hospital & Parkview Kosciusko Hospital | Columbia City, IN | $229.50 | $180.25 – $246.11 |
| Parkview LaGrange Hospital | Lagrange, IN | $231.00 | $215.53 – $287.00 |
| Parkview DeKalb Hospital | Auburn, IN | $233.00 | $180.25 – $246.11 |
| Sentara Leigh Hospital | Norfolk, VA | $233.50 | $64.93 – $658.82 |
| Sentara Virginia Beach General Hospital | Virginia Beach, VA | $233.50 | $64.93 – $658.82 |
| Sentara Princess Anne Hospital | Virginia Beach, VA | $233.50 | $64.93 – $658.82 |
| Sentara Obici Hospital | Suffolk, VA | $233.50 | $64.93 – $658.82 |
| Sentara CarePlex Hospital | Hampton, VA | $233.50 | $64.93 – $174.12 |
| Sentara Northern Virginia Medical Center | Woodbridge, VA | $233.50 | $32.59 – $514.04 |
| Sentara Norfolk General Hospital | Norfolk, VA | $233.50 | $64.93 – $658.82 |
| Parkview Noble Hospital | Kendallville, IN | $234.00 | $180.25 – $246.11 |
| Henry Ford Hospital | Detroit MI 48202 | 19401 Hubbard Dr., MI | $234.27 | $21.62 – $428.13 |
| Henry Ford West Bloomfield Hospital | West Bloomfield, MI | $234.27 | $21.62 – $428.13 |
| Henry Ford Wyandotte Hospital: | Wyandotte, MI | $234.27 | $21.62 – $428.13 |
| Henry Ford Macomb Hospital | Clinton Twp, MI | $234.27 | $21.62 – $421.74 |
| Mercy Hospital Berryville | Berryville, AR | $234.65 | $53.26 – $339.02 |
| Allen Hospital | Oberlin, OH | $236.40 | not published |
| Parkview Wabash Hospital | Wabash, IN | $236.50 | $215.53 – $287.00 |
| Community Hospital | Torrington, WY | $237.36 | $151.36 – $333.68 |
| St. Michael Medical Center | Silverdale, WA | $239.68 | $294.23 – $741.12 |
| UPMC St. Margaret | Pittsburgh, PA | $240.00 | $18.29 – $179.71 |
| Ascension St. John Medical Center (St. John Medical Center, Inc.) | Tulsa, OK | $240.83 | $71.49 – $652.00 |
| Ascension St. John Jane Phillips (Jane Phillips Memorial Medical Center, Inc.) | Bartlesville, OK | $240.83 | $71.49 – $392.78 |
| Ascension St. John Nowata (Jane Phillips Nowata Hospital, Inc.) | Nowata, OK | $240.83 | $71.49 – $133.66 |
| Ascension St. John Sapulpa (St. John Sapulpa, Inc.) | Sapulpa, OK | $240.83 | $71.49 – $133.66 |
| Ascension St. John Broken Arrow (St. John Broken Arrow, Inc.) | Jenks, OK | $240.83 | $71.49 – $133.66 |
| Ascension St. John Owasso (Owasso Medical Facility, Inc.) | Owasso, OK | $240.83 | $71.49 – $366.75 |
| Parkview Regional Medical Center & Parkview Hospital Randallia | Fort Wayne, IN | $241.00 | $180.25 – $246.11 |
| Parkview Ortho Hospital | Fort Wayne, IN | $241.00 | $180.25 – $246.11 |
| MUSC Health Florence Medical Center | Florence, SC | $241.00 | $15.34 – $174.30 |
| Southeastern Medical Center | Cambridge, OH | $241.80 | $161.18 – $167.63 |
| MUSC Health Kershaw Medical Center | Camden, SC | $242.00 | $77.88 – $181.15 |