In situ hybridization per specimen initial single probe stain cost at US hospitals
HC in Situ Hybridization per Specimen Initial Single Probe Stain · CPT 88365
$21.50
lowest cash price
$338.40
national median
$3,057.35
highest cash price
906
hospitals with a published cash price
Middle half of hospitals (25th–75th percentile) against the full range. The same procedure varies $21.50–$3,057.35 — the variation is the story.
Median cash price over time
Sep 1, 2025 ($353.55) → Sep 1, 2026 ($375.41)
By state
| State | Hospitals | Lowest cash | Median | Highest |
|---|---|---|---|---|
| Alaska | 5 | $143.64 | $171.60 | $1,567.02 |
| Arizona | 23 | $65.38 | $159.62 | $603.56 |
| Arkansas | 10 | $54.00 | $234.65 | $627.00 |
| California | 86 | $22.80 | $228.99 | $549.85 |
| Colorado | 14 | $169.59 | $1,813.00 | $2,404.59 |
| Florida | 81 | $43.97 | $455.16 | $2,743.40 |
| Georgia | 25 | $83.18 | $732.42 | $1,963.89 |
| Hawaii | 2 | $160.32 | $160.32 | $435.00 |
| Illinois | 42 | $81.25 | $476.40 | $1,144.50 |
| Indiana | 26 | $188.50 | $902.40 | $1,336.80 |
| Iowa | 26 | $204.10 | $471.20 | $712.00 |
| Kansas | 10 | $903.66 | $1,152.53 | $1,152.53 |
| Kentucky | 22 | $56.00 | $165.70 | $1,283.03 |
| Louisiana | 2 | $136.50 | $136.50 | $136.50 |
| Maine | 7 | $105.90 | $424.00 | $1,100.90 |
| Maryland | 2 | $243.60 | $243.60 | $243.60 |
| Michigan | 27 | $75.20 | $364.00 | $607.20 |
| Minnesota | 18 | $340.00 | $979.20 | $2,344.38 |
| Mississippi | 7 | $58.74 | $72.87 | $386.64 |
| Missouri | 16 | $154.55 | $214.50 | $1,274.43 |
| Montana | 2 | $275.20 | $275.20 | $288.80 |
| Nebraska | 13 | $126.00 | $310.80 | $535.50 |
| Nevada | 3 | $96.35 | $106.69 | $134.42 |
| New Hampshire | 1 | $353.55 | $353.55 | $353.55 |
| New Jersey | 21 | $47.60 | $140.68 | $201.80 |
| New Mexico | 1 | not published by hospital | not published by hospital | not published by hospital |
| New York | 23 | $202.78 | $202.78 | $1,240.00 |
| North Carolina | 14 | $139.00 | $436.88 | $1,846.00 |
| North Dakota | 4 | $338.40 | $338.40 | $372.00 |
| Ohio | 67 | $165.60 | $396.75 | $752.70 |
| Oklahoma | 12 | $100.65 | $240.83 | $432.00 |
| Oregon | 12 | $107.87 | $501.00 | $717.40 |
| Pennsylvania | 30 | $76.20 | $337.20 | $981.00 |
| South Carolina | 11 | $241.00 | $279.00 | $811.00 |
| South Dakota | 7 | $340.00 | $407.20 | $483.20 |
| Tennessee | 37 | $61.80 | $134.85 | $2,108.96 |
| Texas | 116 | $103.60 | $353.40 | $3,057.35 |
| Virginia | 41 | $132.25 | $298.00 | $1,785.00 |
| Washington | 32 | $150.50 | $247.00 | $716.80 |
| West Virginia | 16 | $21.50 | $263.00 | $921.00 |
| Wisconsin | 35 | $175.43 | $322.50 | $1,291.51 |
| Wyoming | 4 | $143.64 | $195.05 | $274.86 |
All hospitals
| Hospital | Location | Cash price | Negotiated range |
|---|---|---|---|
| OSF Saint Paul Medical Center | Mendota, IL | $676.00 | not published |
| Riverside Methodist Hospital | Columbus, OH | $677.30 | $164.27 – $589.69 |
| Dublin Methodist Hospital | Dublin, OH | $677.30 | $164.27 – $589.69 |
| Grant Medical Center | Columbus, OH | $677.30 | $164.27 – $589.69 |
| Doctors Hospital | Columbus, OH | $677.30 | $167.87 – $589.69 |
| Adventhealth Central Texas | Killeen, TX | $684.92 | $171.15 – $552.48 |
| Emory Decatur Hospital | Decatur, GA | $685.00 | $99.96 – $362.28 |
| Emory Hillandale Hospital | Lithonia, GA | $685.00 | $99.96 – $362.28 |
| Emory Long-Term Acute Care Hospital | Decatur, GA | $685.00 | $182.48 – $182.48 |
| Emory Johns Creek Hospital | Johns Creek, GA | $685.00 | $99.96 – $366.86 |
| Emory Rehabilitation Hospital | Atlanta, GA | $685.00 | $99.96 – $199.92 |
| Emory Saint Joseph's Hospital | Atlanta, GA | $685.00 | $99.96 – $366.86 |
| Emory University Hospital | Ne, GA | $685.00 | $99.96 – $362.28 |
| Emory University Hospital Midtown | Atlanta, GA | $685.00 | $99.96 – $366.86 |
| HSHS St. Mary's Hospital | DECATUR, IL | $687.60 | $119.73 – $955.00 |
| Baptist Hospital | MIAMI, FL | $689.00 | $23.70 – $199.26 |
| Bethesda Hospital East | BOYNTON BEACH, FL | $689.00 | $27.54 – $185.03 |
| Doctors Hospital | CORAL GABLES, FL | $689.00 | $23.98 – $199.26 |
| Baptist Health Hospital Doral | SOUTH MIAMI, FL | $689.00 | $23.84 – $195.71 |
| Fishermens Community Hospital | MARATHON, FL | $689.00 | $22.88 – $123.30 |
| Homestead Hospital | HOMESTEAD, FL | $689.00 | $23.29 – $195.71 |
| Mariners Hospital | TAVERNIER, FL | $689.00 | $23.70 – $123.30 |
| West Kendall Baptist Hospital | MIAMI, FL | $689.00 | $23.43 – $199.26 |
| OSF Saint Francis Medical Center | Peoria, IL | $693.60 | $131.94 – $620.67 |
| Clifton Springs Hospital and Clinic | Clifton Springs, NY | $698.23 | $49.29 – $403.60 |
| HCA HealthONE BELMAR ER, A PART OF SWEDISH | LAKEWOOD, CO | $707.17 | $81.87 – $355.00 |
| Sanford Sheldon Medical Center | Sheldon, IA | $712.00 | $253.65 – $801.00 |
| Central Medical Center | Seattle, WA | $716.80 | $662.00 – $662.00 |
| Sunnyside Medical Center | CLACKAMAS, OR | $717.40 | $218.00 – $218.00 |
| Westside Medical Center | HILLSBORO, OR | $717.40 | $218.00 – $218.00 |
| HCA FLORIDA NORTHWEST HOSPITAL | MARGATE, FL | $722.00 | $149.16 – $308.24 |
| HSHS St. Joseph's Hospital | HIGHLAND, IL | $722.16 | $265.39 – $1,003.00 |
| Lincoln Health | Damariscotta, ME | $724.30 | $41.90 – $657.66 |
| Wellstar Cobb Hospital | Austell, GA | $732.42 | $65.18 – $320.14 |
| Wellstar Douglas Hospital | Douglasville, GA | $732.42 | $65.18 – $317.26 |
| Wellstar Kennestone Hospital | Marietta, GA | $732.42 | $65.18 – $320.14 |
| Wellstar MCG Health | Augusta, GA | $732.42 | $46.82 – $303.94 |
| Wellstar North Fulton Hospital | Roswell, GA | $732.42 | $65.18 – $320.14 |
| Wellstar Paulding Hospital | Hiram, GA | $732.42 | $65.18 – $320.14 |
| Wellstar Roosevelt Long Term Acute Care at Warm Springs | P O Box 280, GA | $732.42 | not published |
| Wellstar Spalding Regional Hospital | Griffin, GA | $732.42 | $65.18 – $334.93 |
| Wellstar Sylvan Grove Hospital | Jackson, GA | $732.42 | $65.18 – $482.12 |
| Wellstar West Georgia Medical Center | Lagrange, GA | $732.42 | $65.18 – $328.59 |
| Wellstar Windy Hill Hospital | Marietta, GA | $732.42 | $65.18 – $315.74 |
| Ascension St. Vincent Salem (St. Vincent Salem Hospital, Inc.) | Salem, IN | $738.00 | $18.33 – $195.81 |
| Ascension St. Vincent Williamsport (St. Vincent Williamsport Hospital, Inc.) | Williamsport, IN | $742.80 | $18.33 – $195.81 |
| Grady Memorial Hospital | Delaware, OH | $752.70 | $164.27 – $170.85 |
| SOUTHERN HILLS MEDICAL CENTER | ANTIOCH, TN | $756.44 | $18.39 – $236.00 |
| UPMC Kane | Kane, PA | $760.80 | $38.10 – $563.50 |
| HCA HOUSTON PEARLAND | Pearland, TX | $798.51 | $149.16 – $728.49 |