Methotrexate therapeutic drug level cost at US hospitals
HC Methotrexate Tda · CPT 80204
$5.60
lowest cash price
$105.30
national median
$1,040.00
highest cash price
747
hospitals with a published cash price
Middle half of hospitals (25th–75th percentile) against the full range. The same procedure varies $5.60–$1,040.00 — the variation is the story.
Median cash price over time
Sep 1, 2025 ($84.75) → Sep 1, 2026 ($178.50)
By state
| State | Hospitals | Lowest cash | Median | Highest |
|---|---|---|---|---|
| Alaska | 5 | $46.02 | $48.36 | $355.68 |
| Arizona | 19 | $9.74 | $18.56 | $65.08 |
| Arkansas | 9 | $11.55 | $125.45 | $377.00 |
| California | 85 | $5.60 | $52.80 | $148.41 |
| Colorado | 9 | $26.68 | $218.93 | $551.85 |
| Florida | 78 | $17.00 | $180.05 | $1,016.00 |
| Georgia | 25 | $45.88 | $105.30 | $154.00 |
| Hawaii | 2 | $41.96 | $41.96 | $117.00 |
| Illinois | 42 | $33.00 | $159.60 | $478.80 |
| Indiana | 26 | $162.50 | $165.50 | $201.56 |
| Iowa | 29 | $47.40 | $77.60 | $352.00 |
| Kansas | 10 | $218.60 | $218.60 | $559.77 |
| Kentucky | 17 | $16.20 | $41.40 | $201.56 |
| Louisiana | 4 | not published by hospital | not published by hospital | not published by hospital |
| Maine | 7 | $84.75 | $137.90 | $290.15 |
| Maryland | 1 | not published by hospital | not published by hospital | not published by hospital |
| Michigan | 26 | $50.40 | $100.00 | $259.20 |
| Minnesota | 14 | $69.70 | $81.31 | $108.00 |
| Mississippi | 8 | $15.40 | $18.48 | $40.04 |
| Missouri | 18 | $29.15 | $253.50 | $1,011.17 |
| Montana | 2 | $60.80 | $60.80 | $80.00 |
| Nebraska | 11 | $63.44 | $118.86 | $239.70 |
| Nevada | 3 | $28.91 | $32.01 | $40.33 |
| New Hampshire | 1 | $274.60 | $274.60 | $274.60 |
| New Jersey | 22 | $38.57 | $42.43 | $48.50 |
| New Mexico | 2 | not published by hospital | not published by hospital | not published by hospital |
| New York | 20 | $33.60 | $38.57 | $126.22 |
| North Carolina | 15 | $146.80 | $146.80 | $262.50 |
| North Dakota | 2 | not published by hospital | not published by hospital | not published by hospital |
| Ohio | 66 | $39.60 | $81.60 | $1,040.00 |
| Oklahoma | 17 | $101.75 | $128.05 | $520.85 |
| Oregon | 9 | $41.60 | $155.55 | $155.55 |
| Pennsylvania | 23 | $67.20 | $133.60 | $615.00 |
| South Carolina | 10 | $111.00 | $145.00 | $693.00 |
| South Dakota | 2 | not published by hospital | not published by hospital | not published by hospital |
| Tennessee | 37 | $14.80 | $49.50 | $308.60 |
| Texas | 102 | $53.25 | $148.65 | $982.62 |
| Virginia | 37 | $48.53 | $262.50 | $914.00 |
| Washington | 32 | $22.40 | $91.58 | $148.72 |
| West Virginia | 17 | $16.20 | $322.50 | $516.00 |
| Wisconsin | 30 | $63.80 | $140.00 | $165.00 |
| Wyoming | 4 | $48.72 | $71.34 | $77.14 |
All hospitals
| Hospital | Location | Cash price | Negotiated range |
|---|---|---|---|
| marymount hospital | Garfield Heights, OH | $172.90 | $0.95 – $239.40 |
| medina hospital | Medina, OH | $172.90 | $0.95 – $239.40 |
| mercy hospital | Canton, OH | $172.90 | $1.11 – $239.40 |
| south pointe hospital | Warrensville Heights, OH | $172.90 | $0.95 – $239.40 |
| OSF Little Company of Mary Medical Center | Evergreen Park, IL | $177.60 | $34.71 – $71.74 |
| HCA FLORIDA LAKE CITY HOSPITAL | LIVE OAK, FL | $178.50 | $34.71 – $117.46 |
| cleveland clinic florida weston hospital | Weston, FL | $180.05 | $5.81 – $235.45 |
| martin north hospital | Stuart, FL | $180.05 | $6.12 – $207.75 |
| indian river hospital | Vero Beach, FL | $180.05 | $5.81 – $221.60 |
| UPMC Bedford | Everett, PA | $180.60 | $13.92 – $270.90 |
| Northwestern Medicine Marianjoy Rehabilitation Hospital | Wheaton, IL | $183.40 | not published |
| Northwestern Medicine Palos Hospital | Palos Heights, IL | $183.40 | not published |
| SSM Health St. Anthony Hospital - Midwest | Midwest City, OK | $188.65 | $38.57 – $82.54 |
| UPMC Altoona | Altoona, PA | $189.00 | $28.79 – $252.00 |
| Northwestern Medicine Kishwaukee Hospital | DeKalb, IL | $193.20 | not published |
| Stephens Memorial Hospital | Norway, ME | $197.00 | $24.70 – $185.18 |
| MercyOne Centerville Medical Center | Centerville, IA | $197.00 | $54.06 – $197.00 |
| Love County Health Center | Marietta, OK | $200.00 | $34.31 – $34.31 |
| Inova Alexandria Hospital | Alexandria, VA | $201.00 | $14.43 – $252.90 |
| Inova Fairfax Hospital | Falls Church, VA | $201.00 | $14.43 – $252.90 |
| Inova Fair Oaks Hospital | VA 22033-1709, VA | $201.00 | $14.43 – $252.90 |
| Inova Loudoun Hospital | Leesburg, VA | $201.00 | $14.43 – $252.90 |
| Inova Mount Vernon Hospital | Alexandria, VA | $201.00 | $14.43 – $252.90 |
| OSF St Mary Medical Center | Galesburg, IL | $201.00 | $38.57 – $39.34 |
| AdventHealth Polk | Columbus, NC | $201.39 | not published |
| Baptist Health Floyd | New Albany, IN | $201.56 | $15.43 – $403.13 |
| Baptist Health Hardin | Elizabethtown, KY | $201.56 | $15.43 – $537.50 |
| Baptist Health Corbin | Corbin, KY | $201.56 | $15.43 – $537.50 |
| Baptist Health La Grange | La Grange, KY | $201.56 | $15.43 – $537.50 |
| Baptist Health Lexington | Lexington, KY | $201.56 | $15.43 – $546.37 |
| Baptist Health Louisville | Louisville, KY | $201.56 | $15.43 – $537.50 |
| Baptist Health Paducah | Paducah, KY | $201.56 | $15.43 – $537.50 |
| UPMC East | Monroeville, PA | $203.40 | $29.07 – $271.20 |
| HCA FLORIDA ORANGE PARK HOSPITAL | MIDDLEBURG, FL | $206.71 | $30.86 – $121.08 |
| OSF Saint Francis Medical Center | Peoria, IL | $213.00 | $38.57 – $82.15 |
| Houston Methodist Sugar Land Hospital | Sugar Land, TX | $214.00 | $38.57 – $160.45 |
| Houston Methodist West Hospital | Houston, TX | $214.00 | $38.57 – $160.45 |
| Houston Methodist Baytown Hospital | Baytown, TX | $214.00 | $38.57 – $160.45 |
| Houston Methodist Willowbrook Hospital | Houston, TX | $214.00 | $38.57 – $160.45 |
| Houston Methodist Clear Lake Hospital | Nassau Bay, TX | $214.00 | $38.57 – $75.21 |
| Houston Methodist The Woodlands Hospital | The Woodlands, TX | $214.00 | $38.57 – $160.45 |
| Houston Methodist Continuing Care Hospital | Katy, TX | $214.00 | not published |
| Houston Methodist Cypress Hospital | Cypress, TX | $214.00 | $38.57 – $160.45 |
| OSF Saint Clare Medical Center | Princeton, IL | $217.60 | not published |
| Adventhealth Shawnee Mission | Shawnee Mission, KS | $218.60 | $16.20 – $111.85 |
| Adventhealth South Overland Park | Overland Park, KS | $218.60 | $16.20 – $111.85 |
| Adventhealth Ottawa | Ottawa, KS | $218.60 | $16.20 – $65.57 |
| AdventHealth Parker | Parker, CO | $218.93 | $37.80 – $71.35 |
| AdventHealth Castle Rock | Castle Rock, CO | $218.93 | $37.80 – $71.35 |
| AdventHealth Littleton | Littleton, CO | $218.93 | $37.80 – $71.35 |