Methotrexate therapeutic drug level cost at US hospitals
HC Methotrexate Tda · CPT 80204
$5.60
lowest cash price
$105.30
national median
$1,040.00
highest cash price
747
hospitals with a published cash price
Middle half of hospitals (25th–75th percentile) against the full range. The same procedure varies $5.60–$1,040.00 — the variation is the story.
Median cash price over time
Sep 1, 2025 ($84.75) → Sep 1, 2026 ($178.50)
By state
| State | Hospitals | Lowest cash | Median | Highest |
|---|---|---|---|---|
| Alaska | 5 | $46.02 | $48.36 | $355.68 |
| Arizona | 19 | $9.74 | $18.56 | $65.08 |
| Arkansas | 9 | $11.55 | $125.45 | $377.00 |
| California | 85 | $5.60 | $52.80 | $148.41 |
| Colorado | 9 | $26.68 | $218.93 | $551.85 |
| Florida | 78 | $17.00 | $180.05 | $1,016.00 |
| Georgia | 25 | $45.88 | $105.30 | $154.00 |
| Hawaii | 2 | $41.96 | $41.96 | $117.00 |
| Illinois | 42 | $33.00 | $159.60 | $478.80 |
| Indiana | 26 | $162.50 | $165.50 | $201.56 |
| Iowa | 29 | $47.40 | $77.60 | $352.00 |
| Kansas | 10 | $218.60 | $218.60 | $559.77 |
| Kentucky | 17 | $16.20 | $41.40 | $201.56 |
| Louisiana | 4 | not published by hospital | not published by hospital | not published by hospital |
| Maine | 7 | $84.75 | $137.90 | $290.15 |
| Maryland | 1 | not published by hospital | not published by hospital | not published by hospital |
| Michigan | 26 | $50.40 | $100.00 | $259.20 |
| Minnesota | 14 | $69.70 | $81.31 | $108.00 |
| Mississippi | 8 | $15.40 | $18.48 | $40.04 |
| Missouri | 18 | $29.15 | $253.50 | $1,011.17 |
| Montana | 2 | $60.80 | $60.80 | $80.00 |
| Nebraska | 11 | $63.44 | $118.86 | $239.70 |
| Nevada | 3 | $28.91 | $32.01 | $40.33 |
| New Hampshire | 1 | $274.60 | $274.60 | $274.60 |
| New Jersey | 22 | $38.57 | $42.43 | $48.50 |
| New Mexico | 2 | not published by hospital | not published by hospital | not published by hospital |
| New York | 20 | $33.60 | $38.57 | $126.22 |
| North Carolina | 15 | $146.80 | $146.80 | $262.50 |
| North Dakota | 2 | not published by hospital | not published by hospital | not published by hospital |
| Ohio | 66 | $39.60 | $81.60 | $1,040.00 |
| Oklahoma | 17 | $101.75 | $128.05 | $520.85 |
| Oregon | 9 | $41.60 | $155.55 | $155.55 |
| Pennsylvania | 23 | $67.20 | $133.60 | $615.00 |
| South Carolina | 10 | $111.00 | $145.00 | $693.00 |
| South Dakota | 2 | not published by hospital | not published by hospital | not published by hospital |
| Tennessee | 37 | $14.80 | $49.50 | $308.60 |
| Texas | 102 | $53.25 | $148.65 | $982.62 |
| Virginia | 37 | $48.53 | $262.50 | $914.00 |
| Washington | 32 | $22.40 | $91.58 | $148.72 |
| West Virginia | 17 | $16.20 | $322.50 | $516.00 |
| Wisconsin | 30 | $63.80 | $140.00 | $165.00 |
| Wyoming | 4 | $48.72 | $71.34 | $77.14 |
All hospitals
| Hospital | Location | Cash price | Negotiated range |
|---|---|---|---|
| AdventHealth Porter | Denver, CO | $218.93 | $37.80 – $71.35 |
| AdventHealth Avista | Louisville, CO | $218.93 | $37.80 – $71.35 |
| Mercy Hospital Carthage | Carthage, MO | $226.85 | $32.78 – $142.82 |
| MercyOne Des Moines Medical Center | Des Moines, IA | $228.80 | $37.37 – $352.00 |
| Parkview Montpelier Hospital | Montpelier, OH | $234.50 | not published |
| Parkview Bryan Hospital | Bryan, OH | $234.50 | $38.57 – $115.71 |
| OSF Sacred Heart Medical Center – Urbana | Danville, IL | $235.80 | $38.57 – $39.34 |
| CHI Health Plainview | Plainview, NE | $236.88 | $38.57 – $276.36 |
| OSF Saint Anthony Medical Center | Rockford, IL | $238.20 | $38.57 – $135.00 |
| CHI Health Schuyler | Schuyler, NE | $239.70 | $38.57 – $276.36 |
| Mercy Hospital Aurora | Aurora, MO | $253.50 | $32.78 – $53.45 |
| Northwestern Lake Forest Hospital DBA Northwestern Medicine Catherine Gratz Griffin Lake Forest Hospital | Lake Forest, IL | $256.90 | not published |
| Northwestern Medicine McHenry Hospital | McHenry, IL | $256.90 | not published |
| Adventhealth Port Charlotte | Port Charlotte, FL | $257.10 | $38.57 – $70.43 |
| OSF St Joseph Medical Center | Bloomington, IL | $258.60 | $38.57 – $39.34 |
| OSF St Francis Hospital | Escanaba, MI | $259.20 | not published |
| Sentara Albemarle Regional Medical Center | Elizabeth City, NC | $262.50 | $38.57 – $39.34 |
| Sentara Halifax Regional Hospital | South Boston, VA | $262.50 | $33.56 – $40.50 |
| Sentara Leigh Hospital | Norfolk, VA | $262.50 | $38.57 – $40.50 |
| Sentara Virginia Beach General Hospital | Virginia Beach, VA | $262.50 | $38.57 – $40.50 |
| Sentara Princess Anne Hospital | Virginia Beach, VA | $262.50 | $38.57 – $40.50 |
| Sentara Obici Hospital | Suffolk, VA | $262.50 | $38.57 – $72.12 |
| Sentara CarePlex Hospital | Hampton, VA | $262.50 | $38.57 – $40.50 |
| Sentara Northern Virginia Medical Center | Woodbridge, VA | $262.50 | $23.14 – $55.17 |
| Sentara Norfolk General Hospital | Norfolk, VA | $262.50 | $38.57 – $40.50 |
| Dell Children's Medical Center (Ascension Seton) | Austin, TX | $265.65 | $32.40 – $181.66 |
| HCA HOUSTON PEARLAND | Pearland, TX | $265.71 | $32.40 – $158.91 |
| OSF Saint James John W Albrecht Medical Center | Pontiac, IL | $270.40 | $38.57 – $39.34 |
| MaineHealth - Memorial Hospital | North Conway, NH | $274.60 | $15.43 – $205.86 |
| Baptist Hospital | MIAMI, FL | $282.10 | $6.36 – $390.60 |
| Bethesda Hospital East | BOYNTON BEACH, FL | $282.10 | $6.36 – $390.60 |
| Doctors Hospital | CORAL GABLES, FL | $282.10 | $6.16 – $390.60 |
| Baptist Health Hospital Doral | SOUTH MIAMI, FL | $282.10 | $6.16 – $390.60 |
| Fishermens Community Hospital | MARATHON, FL | $282.10 | $6.16 – $390.60 |
| Homestead Hospital | HOMESTEAD, FL | $282.10 | $6.16 – $390.60 |
| Mariners Hospital | TAVERNIER, FL | $282.10 | $6.16 – $390.60 |
| West Kendall Baptist Hospital | MIAMI, FL | $282.10 | $6.16 – $390.60 |
| LAFAYETTE REGIONAL HEALTH CENTER | Lexington, MO | $285.83 | $32.78 – $38.57 |
| HCA FLORIDA PALMS WEST HOSPITAL | LOXAHATCHEE, FL | $287.00 | $38.18 – $233.35 |
| HCA FLORIDA MERCY HOSPITAL | MIAMI, FL | $289.00 | $38.18 – $132.02 |
| Waldo County General Hospital | Belfast, ME | $290.15 | $24.70 – $273.32 |
| SSM Health St. Anthony Hospital - Shawnee | Shawnee, OK | $290.40 | $38.57 – $56.55 |
| UPMC St. Margaret | Pittsburgh, PA | $298.80 | $29.07 – $42.43 |
| Northwestern Medicine Central DuPage Hospital | IL 60190, IL | $305.90 | not published |
| Northwestern Medicine Delnor Hospital | Geneva, IL | $305.90 | not published |
| SUMMIT MEDICAL CENTER | MT JULIET, TN | $308.60 | $17.36 – $115.71 |
| HCA FLORIDA KENDALL HOSPITAL | DORAL, FL | $311.00 | $38.18 – $132.02 |
| United Hospital Center | Bridgeport, WV | $322.50 | $36.45 – $60.94 |
| Berkeley Medical Center | Martinsburg, WV | $322.50 | $36.45 – $60.94 |
| Camden Clark Medical Center | Parkersburg, WV | $322.50 | $36.45 – $60.94 |