Methotrexate therapeutic drug level cost at US hospitals
HC Methotrexate Tda · CPT 80204
$5.60
lowest cash price
$105.30
national median
$1,040.00
highest cash price
747
hospitals with a published cash price
Middle half of hospitals (25th–75th percentile) against the full range. The same procedure varies $5.60–$1,040.00 — the variation is the story.
Median cash price over time
Sep 1, 2025 ($84.75) → Sep 1, 2026 ($178.50)
By state
| State | Hospitals | Lowest cash | Median | Highest |
|---|---|---|---|---|
| Alaska | 5 | $46.02 | $48.36 | $355.68 |
| Arizona | 19 | $9.74 | $18.56 | $65.08 |
| Arkansas | 9 | $11.55 | $125.45 | $377.00 |
| California | 85 | $5.60 | $52.80 | $148.41 |
| Colorado | 9 | $26.68 | $218.93 | $551.85 |
| Florida | 78 | $17.00 | $180.05 | $1,016.00 |
| Georgia | 25 | $45.88 | $105.30 | $154.00 |
| Hawaii | 2 | $41.96 | $41.96 | $117.00 |
| Illinois | 42 | $33.00 | $159.60 | $478.80 |
| Indiana | 26 | $162.50 | $165.50 | $201.56 |
| Iowa | 29 | $47.40 | $77.60 | $352.00 |
| Kansas | 10 | $218.60 | $218.60 | $559.77 |
| Kentucky | 17 | $16.20 | $41.40 | $201.56 |
| Louisiana | 4 | not published by hospital | not published by hospital | not published by hospital |
| Maine | 7 | $84.75 | $137.90 | $290.15 |
| Maryland | 1 | not published by hospital | not published by hospital | not published by hospital |
| Michigan | 26 | $50.40 | $100.00 | $259.20 |
| Minnesota | 14 | $69.70 | $81.31 | $108.00 |
| Mississippi | 8 | $15.40 | $18.48 | $40.04 |
| Missouri | 18 | $29.15 | $253.50 | $1,011.17 |
| Montana | 2 | $60.80 | $60.80 | $80.00 |
| Nebraska | 11 | $63.44 | $118.86 | $239.70 |
| Nevada | 3 | $28.91 | $32.01 | $40.33 |
| New Hampshire | 1 | $274.60 | $274.60 | $274.60 |
| New Jersey | 22 | $38.57 | $42.43 | $48.50 |
| New Mexico | 2 | not published by hospital | not published by hospital | not published by hospital |
| New York | 20 | $33.60 | $38.57 | $126.22 |
| North Carolina | 15 | $146.80 | $146.80 | $262.50 |
| North Dakota | 2 | not published by hospital | not published by hospital | not published by hospital |
| Ohio | 66 | $39.60 | $81.60 | $1,040.00 |
| Oklahoma | 17 | $101.75 | $128.05 | $520.85 |
| Oregon | 9 | $41.60 | $155.55 | $155.55 |
| Pennsylvania | 23 | $67.20 | $133.60 | $615.00 |
| South Carolina | 10 | $111.00 | $145.00 | $693.00 |
| South Dakota | 2 | not published by hospital | not published by hospital | not published by hospital |
| Tennessee | 37 | $14.80 | $49.50 | $308.60 |
| Texas | 102 | $53.25 | $148.65 | $982.62 |
| Virginia | 37 | $48.53 | $262.50 | $914.00 |
| Washington | 32 | $22.40 | $91.58 | $148.72 |
| West Virginia | 17 | $16.20 | $322.50 | $516.00 |
| Wisconsin | 30 | $63.80 | $140.00 | $165.00 |
| Wyoming | 4 | $48.72 | $71.34 | $77.14 |
All hospitals
| Hospital | Location | Cash price | Negotiated range |
|---|---|---|---|
| MUSC Health Kershaw Medical Center | Camden, SC | $148.00 | $38.57 – $42.43 |
| Santa Rosa Memorial Hospital | Santa Rosa, CA | $148.41 | $37.80 – $114.87 |
| Texas Health Harris Methodist Hospital Alliance | Fort Worth, TX | $148.65 | $32.40 – $38.57 |
| Texas Health Arlington Memorial Hospital | Arlington, TX | $148.65 | $32.40 – $38.57 |
| Texas Health Presbyterian Hospital Allen | Allen, TX | $148.65 | $32.40 – $95.78 |
| Texas Health Center for Diagnostics and Surgery Plano | Plano, TX | $148.65 | $32.40 – $95.78 |
| Texas Health Harris Methodist Hospital Azle | Azle, TX | $148.65 | $32.40 – $38.57 |
| Texas Health Presbyterian Hospital Denton | Denton, TX | $148.65 | $32.40 – $38.57 |
| Texas Health Heart & Vascular Hospital Arlington | Arlington, TX | $148.65 | $32.40 – $38.57 |
| Texas Health Presbyterian Hospital Kaufman | Kaufman, TX | $148.65 | $32.40 – $95.78 |
| Texas Health Harris Methodist Hospital Hurst-Euless-Bedford | Bedford, TX | $148.65 | $32.40 – $38.57 |
| Texas Health Presbyterian Hospital Plano | Plano, TX | $148.65 | $32.40 – $95.78 |
| Texas Health Hospital Rockwall | Rockwall, TX | $148.65 | $32.40 – $95.78 |
| Texas Health Harris Methodist Hospital Southwest Fort Worth | Fort Worth, TX | $148.65 | $32.40 – $38.57 |
| Texas Health Harris Methodist Hospital Fort Worth | Fort Worth, TX | $148.65 | $32.40 – $38.57 |
| Texas Health Harris Methodist Hospital Stephenville | Stephenville, TX | $148.65 | $38.57 – $95.78 |
| Texas Health Harris Methodist Hospital Cleburne | Cleburne, TX | $148.65 | $32.40 – $38.57 |
| Providence Regional Medical Center Everett - Colby Campus | Everett, WA | $148.72 | $38.57 – $89.48 |
| Franklin Memorial Hospital | Farmington, ME | $149.60 | $21.88 – $140.62 |
| Emory Hospital Perry | Perry, GA | $154.00 | $28.93 – $81.77 |
| Emory Hospital Warner Robins | Warner Robins, GA | $154.00 | $28.93 – $81.77 |
| Mercy Hospital Ardmore | Northwest Ardmore, OK | $154.70 | $34.31 – $85.14 |
| Sunnyside Medical Center | CLACKAMAS, OR | $155.55 | $47.00 – $47.00 |
| Westside Medical Center | HILLSBORO, OR | $155.55 | $47.00 – $47.00 |
| Ascension Seton Edgar B. Davis (Ascension Seton) | Luling, TX | $159.03 | $32.40 – $198.79 |
| Ascension Seton Highland Lakes (Ascension Seton) | Burnet, TX | $159.03 | $32.40 – $198.79 |
| OSF Saint Anthony's Health Center | Alton, IL | $159.60 | $23.14 – $39.34 |
| OSF Holy Family Medical Center | Monmouth, IL | $161.60 | not published |
| Parkview Huntington Hospital | Huntington, IN | $162.50 | $38.57 – $57.86 |
| Parkview Whitley Hospital & Parkview Kosciusko Hospital | Columbia City, IN | $162.50 | $38.57 – $57.86 |
| Parkview LaGrange Hospital | Lagrange, IN | $163.50 | $69.22 – $77.14 |
| Adventhealth Fish Memorial | Orange City, FL | $164.36 | $36.64 – $73.41 |
| SSM Health St. Mary's Hospital - Janesville | Janesville, WI | $165.00 | $28.93 – $225.15 |
| Parkview DeKalb Hospital | Auburn, IN | $165.00 | $38.57 – $57.86 |
| Parkview Noble Hospital | Kendallville, IN | $165.50 | $38.57 – $57.86 |
| Parkview Wabash Hospital | Wabash, IN | $167.50 | $69.22 – $77.14 |
| OSF Saint Paul Medical Center | Mendota, IL | $168.00 | not published |
| OSF Healthcare Saint Katharine Medical Center | Dixon, IL | $169.40 | $38.57 – $38.57 |
| Mercy Hospital Lincoln | Troy, MO | $169.65 | $38.57 – $53.45 |
| Parkwest Medical Center | Knoxville, TN | $170.10 | $17.36 – $243.00 |
| Parkview Regional Medical Center & Parkview Hospital Randallia | Fort Wayne, IN | $170.50 | $38.57 – $57.86 |
| Parkview Ortho Hospital | Fort Wayne, IN | $170.50 | $38.57 – $57.86 |
| Adventhealth North Pinellas | Tarpon Springs, FL | $172.50 | $38.57 – $85.63 |
| cleveland clinic main campus | Cleveland, OH | $172.90 | $15.43 – $239.40 |
| akron general | Akron, OH | $172.90 | $0.95 – $239.40 |
| avon hospital | Avon, OH | $172.90 | $0.95 – $239.40 |
| euclid hospital | Euclid, OH | $172.90 | $0.95 – $239.40 |
| fairview hospital | Cleveland, OH | $172.90 | $0.95 – $239.40 |
| lutheran hospital | Cleveland, OH | $172.90 | $0.95 – $239.40 |
| hillcrest hospital | Mayfield Heights, OH | $172.90 | $0.95 – $239.40 |