Methotrexate therapeutic drug level cost at US hospitals
HC Methotrexate Tda · CPT 80204
$5.60
lowest cash price
$105.30
national median
$1,040.00
highest cash price
747
hospitals with a published cash price
Middle half of hospitals (25th–75th percentile) against the full range. The same procedure varies $5.60–$1,040.00 — the variation is the story.
Median cash price over time
Sep 1, 2025 ($84.75) → Sep 1, 2026 ($178.50)
By state
| State | Hospitals | Lowest cash | Median | Highest |
|---|---|---|---|---|
| Alaska | 5 | $46.02 | $48.36 | $355.68 |
| Arizona | 19 | $9.74 | $18.56 | $65.08 |
| Arkansas | 9 | $11.55 | $125.45 | $377.00 |
| California | 85 | $5.60 | $52.80 | $148.41 |
| Colorado | 9 | $26.68 | $218.93 | $551.85 |
| Florida | 78 | $17.00 | $180.05 | $1,016.00 |
| Georgia | 25 | $45.88 | $105.30 | $154.00 |
| Hawaii | 2 | $41.96 | $41.96 | $117.00 |
| Illinois | 42 | $33.00 | $159.60 | $478.80 |
| Indiana | 26 | $162.50 | $165.50 | $201.56 |
| Iowa | 29 | $47.40 | $77.60 | $352.00 |
| Kansas | 10 | $218.60 | $218.60 | $559.77 |
| Kentucky | 17 | $16.20 | $41.40 | $201.56 |
| Louisiana | 4 | not published by hospital | not published by hospital | not published by hospital |
| Maine | 7 | $84.75 | $137.90 | $290.15 |
| Maryland | 1 | not published by hospital | not published by hospital | not published by hospital |
| Michigan | 26 | $50.40 | $100.00 | $259.20 |
| Minnesota | 14 | $69.70 | $81.31 | $108.00 |
| Mississippi | 8 | $15.40 | $18.48 | $40.04 |
| Missouri | 18 | $29.15 | $253.50 | $1,011.17 |
| Montana | 2 | $60.80 | $60.80 | $80.00 |
| Nebraska | 11 | $63.44 | $118.86 | $239.70 |
| Nevada | 3 | $28.91 | $32.01 | $40.33 |
| New Hampshire | 1 | $274.60 | $274.60 | $274.60 |
| New Jersey | 22 | $38.57 | $42.43 | $48.50 |
| New Mexico | 2 | not published by hospital | not published by hospital | not published by hospital |
| New York | 20 | $33.60 | $38.57 | $126.22 |
| North Carolina | 15 | $146.80 | $146.80 | $262.50 |
| North Dakota | 2 | not published by hospital | not published by hospital | not published by hospital |
| Ohio | 66 | $39.60 | $81.60 | $1,040.00 |
| Oklahoma | 17 | $101.75 | $128.05 | $520.85 |
| Oregon | 9 | $41.60 | $155.55 | $155.55 |
| Pennsylvania | 23 | $67.20 | $133.60 | $615.00 |
| South Carolina | 10 | $111.00 | $145.00 | $693.00 |
| South Dakota | 2 | not published by hospital | not published by hospital | not published by hospital |
| Tennessee | 37 | $14.80 | $49.50 | $308.60 |
| Texas | 102 | $53.25 | $148.65 | $982.62 |
| Virginia | 37 | $48.53 | $262.50 | $914.00 |
| Washington | 32 | $22.40 | $91.58 | $148.72 |
| West Virginia | 17 | $16.20 | $322.50 | $516.00 |
| Wisconsin | 30 | $63.80 | $140.00 | $165.00 |
| Wyoming | 4 | $48.72 | $71.34 | $77.14 |
All hospitals
| Hospital | Location | Cash price | Negotiated range |
|---|---|---|---|
| Adventhealth Daytona Beach | Daytona Beach, FL | $133.96 | $36.64 – $64.37 |
| Adventhealth Palm Coast | Palm Coast, FL | $133.96 | $36.64 – $82.38 |
| Adventhealth Palm Coast Parkway | Palm Coast, FL | $133.96 | $36.64 – $82.38 |
| AdventHealth Deland | Deland, FL | $133.96 | $36.64 – $76.92 |
| UPMC Horizon-Greenville | Greenville, PA | $134.40 | $34.53 – $46.56 |
| MUSC Health Black River Medical Center | Cades, SC | $134.50 | $16.20 – $42.43 |
| CHI Health Mercy Corning | Corning, IA | $135.36 | $38.57 – $276.36 |
| CHI Health St. Elizabeth | Lincoln, NE | $136.00 | $23.23 – $85.63 |
| Ascension Seton Smithville (Ascension Seton) | Smithville, TX | $136.62 | $32.40 – $181.66 |
| Swedish Medical Center Cherry Hill | Seattle, WA | $137.28 | $34.71 – $90.25 |
| Swedish Medical Center - First Hill Campus | Seattle, WA | $137.28 | $34.71 – $117.18 |
| Swedish Issaquah | Issaquah, WA | $137.28 | $34.71 – $85.63 |
| Swedish Edmonds Hospital | Edmonds, WA | $137.28 | $38.57 – $75.21 |
| Lincoln Health | Damariscotta, ME | $137.90 | $24.70 – $129.63 |
| CHI Health Missouri Valley | Missouri Valley, IA | $138.18 | $38.57 – $276.36 |
| SSM Health St. Clare Hospital - Baraboo | Baraboo, WI | $138.60 | $28.93 – $281.44 |
| SSM Health Monroe Hospital | Monroe, WI | $138.60 | $38.57 – $67.50 |
| UPMC Northwest | Seneca, PA | $139.80 | $34.98 – $41.66 |
| Aurora Baycare Medical Center | Green Bay, WI | $140.00 | $30.86 – $124.97 |
| Aurora Medical Center Bay Area | Marinette, WI | $140.00 | $30.86 – $124.97 |
| Aurora Medical Center Burlington | Burlington, WI | $140.00 | $30.86 – $124.97 |
| Aurora Medical Center Grafton | Grafton, WI | $140.00 | $30.86 – $124.97 |
| Aurora Medical Center Manitowoc | Two Rivers, WI | $140.00 | $30.86 – $124.97 |
| Aurora Medical Center Kenosha | Kenosha, WI | $140.00 | $30.86 – $124.97 |
| Aurora Medical Center Fond du Lac | Fond Du Lac, WI | $140.00 | $30.86 – $124.97 |
| Aurora Medical Center Sheboygan County | Sheboygan, WI | $140.00 | $30.86 – $124.97 |
| Aurora Sinai Medical Center of Aurora Health Care Metro | Milwaukee, WI | $140.00 | $30.86 – $124.97 |
| Aurora Medical Center Summit | Summit, WI | $140.00 | $30.86 – $124.97 |
| Aurora Medical Center Washington County | Hartford, WI | $140.00 | $30.86 – $124.97 |
| Aurora West Allis Medical Center | West Allis, WI | $140.00 | $30.86 – $124.97 |
| Mercy Orthopedic Hospital Springfield | Ozark, MO | $140.40 | $17.48 – $74.05 |
| CHI Health St. Francis | Grand Island, NE | $142.78 | $37.37 – $227.48 |
| Providence Holy Family Hospital | Spokane, WA | $144.90 | $38.57 – $164.62 |
| MUSC Health Main Campus - Charleston | Charleston, SC | $145.00 | $38.57 – $42.43 |
| MUSC Health Orangeburg Medical Center | Orangeburg, SC | $145.00 | $38.57 – $42.43 |
| SSM Health St. Mary's Hospital - Madison | Madison, WI | $145.75 | $28.93 – $230.27 |
| HCA FLORIDA JFK HOSPITAL | PALM BEACH GARDENS, FL | $146.00 | $36.64 – $127.13 |
| AdventHealth New Smyrna Beach | New Smyrna Beach, FL | $146.72 | $36.64 – $84.26 |
| Atrium Health Anson | Wadesboro, NC | $146.80 | $18.30 – $278.92 |
| Atrium Health Mercy | Charlotte, NC | $146.80 | $18.30 – $270.11 |
| Atrium Health Pineville | Charlotte, NC | $146.80 | $18.30 – $270.11 |
| Atrium Health Stanly | Albermarle, NC | $146.80 | $18.30 – $281.86 |
| Atrium Health Behavioral Health Charlotte | Charlotte, NC | $146.80 | $18.48 – $258.37 |
| Atrium Health Cleveland | Shelby, NC | $146.80 | $18.30 – $278.92 |
| Atrium Health Cabarrus | Concord, NC | $146.80 | $18.30 – $278.92 |
| Atrium Health Lincoln | Lincolnton, NC | $146.80 | $18.30 – $278.92 |
| Atrium Health Union | Monroe, NC | $146.80 | $18.30 – $278.92 |
| Carolinas Rehabilitation Charlotte | Charlotte, NC | $146.80 | $18.48 – $270.11 |
| Atrium Health University City | Charlotte, NC | $146.80 | $18.30 – $270.11 |
| Atrium Health Carolinas Medical Center | Charlotte, NC | $146.80 | $18.30 – $264.24 |