Methotrexate therapeutic drug level cost at US hospitals
HC Methotrexate Tda · CPT 80204
$5.60
lowest cash price
$105.30
national median
$1,040.00
highest cash price
747
hospitals with a published cash price
Middle half of hospitals (25th–75th percentile) against the full range. The same procedure varies $5.60–$1,040.00 — the variation is the story.
Median cash price over time
Sep 1, 2025 ($84.75) → Sep 1, 2026 ($178.50)
By state
| State | Hospitals | Lowest cash | Median | Highest |
|---|---|---|---|---|
| Alaska | 5 | $46.02 | $48.36 | $355.68 |
| Arizona | 19 | $9.74 | $18.56 | $65.08 |
| Arkansas | 9 | $11.55 | $125.45 | $377.00 |
| California | 85 | $5.60 | $52.80 | $148.41 |
| Colorado | 9 | $26.68 | $218.93 | $551.85 |
| Florida | 78 | $17.00 | $180.05 | $1,016.00 |
| Georgia | 25 | $45.88 | $105.30 | $154.00 |
| Hawaii | 2 | $41.96 | $41.96 | $117.00 |
| Illinois | 42 | $33.00 | $159.60 | $478.80 |
| Indiana | 26 | $162.50 | $165.50 | $201.56 |
| Iowa | 29 | $47.40 | $77.60 | $352.00 |
| Kansas | 10 | $218.60 | $218.60 | $559.77 |
| Kentucky | 17 | $16.20 | $41.40 | $201.56 |
| Louisiana | 4 | not published by hospital | not published by hospital | not published by hospital |
| Maine | 7 | $84.75 | $137.90 | $290.15 |
| Maryland | 1 | not published by hospital | not published by hospital | not published by hospital |
| Michigan | 26 | $50.40 | $100.00 | $259.20 |
| Minnesota | 14 | $69.70 | $81.31 | $108.00 |
| Mississippi | 8 | $15.40 | $18.48 | $40.04 |
| Missouri | 18 | $29.15 | $253.50 | $1,011.17 |
| Montana | 2 | $60.80 | $60.80 | $80.00 |
| Nebraska | 11 | $63.44 | $118.86 | $239.70 |
| Nevada | 3 | $28.91 | $32.01 | $40.33 |
| New Hampshire | 1 | $274.60 | $274.60 | $274.60 |
| New Jersey | 22 | $38.57 | $42.43 | $48.50 |
| New Mexico | 2 | not published by hospital | not published by hospital | not published by hospital |
| New York | 20 | $33.60 | $38.57 | $126.22 |
| North Carolina | 15 | $146.80 | $146.80 | $262.50 |
| North Dakota | 2 | not published by hospital | not published by hospital | not published by hospital |
| Ohio | 66 | $39.60 | $81.60 | $1,040.00 |
| Oklahoma | 17 | $101.75 | $128.05 | $520.85 |
| Oregon | 9 | $41.60 | $155.55 | $155.55 |
| Pennsylvania | 23 | $67.20 | $133.60 | $615.00 |
| South Carolina | 10 | $111.00 | $145.00 | $693.00 |
| South Dakota | 2 | not published by hospital | not published by hospital | not published by hospital |
| Tennessee | 37 | $14.80 | $49.50 | $308.60 |
| Texas | 102 | $53.25 | $148.65 | $982.62 |
| Virginia | 37 | $48.53 | $262.50 | $914.00 |
| Washington | 32 | $22.40 | $91.58 | $148.72 |
| West Virginia | 17 | $16.20 | $322.50 | $516.00 |
| Wisconsin | 30 | $63.80 | $140.00 | $165.00 |
| Wyoming | 4 | $48.72 | $71.34 | $77.14 |
All hospitals
| Hospital | Location | Cash price | Negotiated range |
|---|---|---|---|
| OSF Saint Elizabeth Medical Center | Ottawa, IL | $120.00 | $38.57 – $39.34 |
| MUSC Health Chester Medical Center | Chester, SC | $121.00 | $16.20 – $42.43 |
| Midwest Orthopedic Specialty Hospital | Franklin, WI | $121.90 | $38.57 – $90.64 |
| Ascension St. Francis Hospital, Inc. | Milwaukee, WI | $121.90 | $38.57 – $90.64 |
| Ascension SE Wisconsin Hospital - St. Joseph Campus | Milwaukee, WI | $121.90 | $38.57 – $90.64 |
| BAYLOR SCOTT & WHITE MEDICAL CENTER - BUDA | Suite 110, TX | $122.30 | $12.00 – $152.87 |
| BAYLOR SCOTT & WHITE MEDICAL CENTER - PFLUGERVILLE | Suite 100, TX | $122.30 | $12.00 – $199.41 |
| BAYLOR SCOTT & WHITE EMERGENCY MEDICAL CENTER - CEDAR PARK | Cedar Park, TX | $122.30 | $12.00 – $183.45 |
| BAYLOR SCOTT & WHITE MEDICAL CENTER - TAYLOR | Taylor, TX | $122.30 | $12.00 – $163.06 |
| Kadlec Regional Medical Center | Richland, WA | $122.50 | $38.57 – $71.35 |
| CHI Health Nebraska Heart | Lincoln, NE | $123.28 | $37.37 – $219.76 |
| Ascension Seton Northwest (Ascension Seton) | Austin, TX | $124.02 | $32.40 – $181.66 |
| Dell Seton Medical Center at The University of Texas (Ascension Seton) | Austin, TX | $124.02 | $32.40 – $181.66 |
| Ascension Seton Medical Center Austin (Ascension Seton) | Austin, TX | $124.02 | $32.40 – $181.66 |
| UPMC Community Osteopathic | Harrisburg, PA | $124.20 | $26.00 – $163.13 |
| UPMC Hanover | Hanover, PA | $124.20 | $19.63 – $163.13 |
| UPMC Lititz | Lititz, PA | $124.20 | $19.63 – $163.13 |
| UPMC Memorial | York, PA | $124.20 | $19.63 – $191.10 |
| UPMC Somerset | Somerset, PA | $124.20 | $27.06 – $41.65 |
| UPMC Carlisle | Carlisle, PA | $124.20 | $17.81 – $110.50 |
| Mercy Hospital Ozark | River Ozark, AR | $125.45 | $34.31 – $60.24 |
| Mercy Hospital Paris | Academy Paris, AR | $125.45 | $34.31 – $60.24 |
| Mercy Hospital Waldron | Waldron, AR | $125.45 | $34.31 – $60.24 |
| Mercy Hospital Boonville | Booneville, AR | $125.45 | $34.31 – $60.24 |
| BAYLOR SCOTT & WHITE MEDICAL CENTER - BRENHAM | Brenham, TX | $126.04 | $12.00 – $189.05 |
| BAYLOR SCOTT & WHITE MEDICAL CENTER - COLLEGE STATION | College Station, TX | $126.04 | $12.00 – $189.05 |
| BAYLOR SCOTT & WHITE CONTINUING CARE HOSPITAL | Temple, TX | $126.04 | $8.00 – $189.05 |
| BAYLOR SCOTT & WHITE MEDICAL CENTER HILLCREST | Waco, TX | $126.04 | $32.40 – $157.54 |
| BAYLOR SCOTT & WHITE MCLANE CHILDREN'S MEDICAL CENTER | Temple, TX | $126.04 | $12.00 – $189.05 |
| The Unity Hospital of Rochester | Rochester, NY | $126.22 | $23.37 – $49.76 |
| Mercy Hospital Logan County | Guthrie, OK | $126.75 | $34.31 – $48.21 |
| MUSC Health Florence Medical Center | Florence, SC | $128.00 | $16.20 – $42.43 |
| Mercy Hospital Watonga | Watonga, OK | $128.05 | $34.31 – $48.21 |
| MercyOne Waterloo Medical Center | Waterloo, IA | $128.05 | $37.37 – $197.00 |
| Mercy Hospital Kingfisher | Kingfisher, OK | $128.05 | $34.31 – $48.21 |
| MercyOne Dubuque Medical Center | Dubuque, IA | $128.05 | $37.37 – $197.00 |
| MercyOne New Hampton Medical Center | New Hampton, IA | $128.05 | $77.99 – $197.00 |
| MercyOne Dyersville Medical Center | Dyersville, IA | $128.05 | $74.47 – $221.74 |
| MercyOne Clinton Medical Center | Clinton, IA | $128.05 | $37.37 – $197.00 |
| MercyOne Cedar Falls Medical Center | Cedar Falls, IA | $128.05 | $37.37 – $197.00 |
| MercyOne Elkader Medical Center | Elkader, IA | $128.05 | $101.40 – $205.90 |
| MercyOne Newton Medical Center | Newton, IA | $128.05 | $37.37 – $197.00 |
| MultiCare Valley Hospital | Spokane Valley, WA | $129.20 | $7.12 – $69.93 |
| MultiCare Deaconess Hospital | Spokane, WA | $129.20 | $7.17 – $69.93 |
| UPMC Mercy | Pittsburgh, PA | $129.60 | $28.79 – $42.43 |
| Mercy Hospital Tishomingo | Tishomingo, OK | $130.00 | $34.31 – $48.21 |
| Mercy Hospital Healdton | Healdton, OK | $130.00 | $34.31 – $48.21 |
| St. Michael Medical Center | Silverdale, WA | $132.37 | $38.57 – $269.92 |
| UPMC Jameson | New Castle, PA | $133.20 | $27.06 – $41.66 |
| WellSpan Chambersburg Hospital | Chambersburg, PA | $133.60 | $19.13 – $171.57 |