Alteplase 100 mg infusion from pyxis vial cost at US hospitals
ALTEPLASE 100 MG INFUSION FROM PYXIS VIAL · HCPCS J2997
$556.56
lowest cash price
$15,857.45
national median
$102,964.26
highest cash price
530
hospitals with a published cash price
Middle half of hospitals (25th–75th percentile) against the full range. The same procedure varies $556.56–$102,964.26 — the variation is the story.
Median cash price over time
Sep 1, 2025 ($21,013.50) → Sep 1, 2026 ($21,257.00)
By state
| State | Hospitals | Lowest cash | Median | Highest |
|---|---|---|---|---|
| Alaska | 5 | $960.10 | $19,668.33 | $45,243.16 |
| Arizona | 4 | $8,025.26 | $8,742.97 | $30,343.35 |
| Arkansas | 8 | $8,219.50 | $17,732.73 | $37,806.50 |
| California | 77 | $570.46 | $13,614.60 | $31,630.68 |
| Colorado | 13 | $2,478.25 | $2,478.25 | $2,478.25 |
| Florida | 70 | $556.56 | $1,488.87 | $20,592.84 |
| Georgia | 15 | $2,312.61 | $2,336.68 | $43,507.20 |
| Hawaii | 1 | $19,012.53 | $19,012.53 | $19,012.53 |
| Illinois | 24 | $979.91 | $25,018.70 | $56,853.12 |
| Indiana | 19 | $1,611.20 | $21,257.00 | $87,556.86 |
| Iowa | 20 | $12,850.08 | $25,477.05 | $25,477.05 |
| Kansas | 5 | $1,863.51 | $1,863.51 | $1,863.51 |
| Kentucky | 25 | $748.42 | $32,310.00 | $87,556.86 |
| Louisiana | 4 | $2,559.30 | $2,559.30 | $2,559.30 |
| Maine | 7 | $834.51 | $14,052.42 | $26,765.42 |
| Maryland | 2 | $9,848.40 | $9,848.40 | $9,848.40 |
| Michigan | 15 | $630.01 | $630.01 | $4,598.72 |
| Minnesota | 15 | $4,197.25 | $12,473.57 | $13,925.31 |
| Mississippi | 1 | $10,982.86 | $10,982.86 | $10,982.86 |
| Missouri | 20 | $17,160.70 | $17,217.91 | $21,450.88 |
| Montana | 2 | $21,626.26 | $21,626.26 | $21,626.26 |
| Nebraska | 12 | $3,906.49 | $17,833.94 | $36,092.49 |
| Nevada | 3 | $1,797.84 | $2,600.22 | $3,627.63 |
| New Hampshire | 1 | $31,580.10 | $31,580.10 | $31,580.10 |
| New Jersey | 12 | not published by hospital | not published by hospital | not published by hospital |
| New Mexico | 2 | $1,358.41 | $1,358.41 | $2,819.32 |
| New York | 3 | $28,799.19 | $28,799.19 | $28,799.19 |
| North Carolina | 13 | $705.99 | $17,085.20 | $17,085.20 |
| North Dakota | 3 | $7,445.27 | $9,173.77 | $13,143.43 |
| Ohio | 64 | $8,580.35 | $31,563.16 | $102,964.26 |
| Oklahoma | 13 | $5,084.26 | $5,084.26 | $36,081.48 |
| Oregon | 12 | $806.03 | $23,342.81 | $26,431.24 |
| Pennsylvania | 19 | $612.00 | $5,517.60 | $40,758.00 |
| South Carolina | 11 | $73,130.99 | $73,130.99 | $81,843.35 |
| South Dakota | 5 | $12,473.57 | $12,473.57 | $23,176.60 |
| Tennessee | 26 | $4,048.17 | $8,997.49 | $11,037.54 |
| Texas | 113 | $604.61 | $15,857.45 | $45,243.16 |
| Virginia | 37 | $4,871.66 | $56,498.32 | $92,403.78 |
| Washington | 23 | $635.31 | $12,548.99 | $24,345.24 |
| West Virginia | 8 | $729.05 | $12,124.70 | $32,310.00 |
| Wisconsin | 8 | not published by hospital | not published by hospital | not published by hospital |
All hospitals
| Hospital | Location | Cash price | Negotiated range |
|---|---|---|---|
| Smyth County Community Hospital | MARION, VA | $4,871.66 | $30.45 – $204.55 |
| Sycamore Shoals Hospital | ELIZABETHTON, TN | $4,871.66 | $30.45 – $204.55 |
| Community Hospital San Bernardino | San Bernardino, CA | $4,959.45 | $67.10 – $1,163.00 |
| CHI Health St. Francis | Grand Island, NE | $5,010.49 | $41.10 – $178.69 |
| Ascension St. John Medical Center (St. John Medical Center, Inc.) | Tulsa, OK | $5,084.26 | $40.76 – $40.76 |
| Ascension St. John Owasso (Owasso Medical Facility, Inc.) | Owasso, OK | $5,084.26 | $34.06 – $34.06 |
| Ascension St. John Jane Phillips (Jane Phillips Memorial Medical Center, Inc.) | Bartlesville, OK | $5,084.26 | $43.86 – $101.25 |
| Ascension St. John Nowata (Jane Phillips Nowata Hospital, Inc.) | Nowata, OK | $5,084.26 | $94.50 – $101.25 |
| Ascension St. John Sapulpa (St. John Sapulpa, Inc.) | Sapulpa, OK | $5,084.26 | $32.15 – $32.15 |
| CHI Health Good Samaritan | Kearney, NE | $5,180.34 | $37.53 – $178.69 |
| UPMC Community Osteopathic | Harrisburg, PA | $5,280.00 | $17.60 – $177.50 |
| UPMC Hanover | Hanover, PA | $5,280.00 | $93.51 – $177.50 |
| UPMC Lititz | Lititz, PA | $5,280.00 | $93.51 – $177.50 |
| UPMC Memorial | York, PA | $5,280.00 | $39.59 – $177.50 |
| UPMC Somerset | Somerset, PA | $5,280.00 | $48.08 – $94.45 |
| UPMC Carlisle | Carlisle, PA | $5,280.00 | $12.06 – $177.50 |
| Northridge Hospital Medical Center | Northridge, CA | $5,426.28 | $65.54 – $419.80 |
| St. Mary Medical Center | Long Beach, CA | $5,453.69 | $65.54 – $1,811.00 |
| UPMC Cole | Coudersport, PA | $5,517.60 | $37.70 – $108.80 |
| Methodist Dallas Medical Center | Dallas, TX | $5,544.25 | $93.83 – $382.87 |
| Methodist Richardson Medical Center | Richardson, TX | $5,544.25 | $93.83 – $253.35 |
| Mercy Medical Center Mt. Shasta | Mt Shasta, CA | $5,770.43 | $91.46 – $599.76 |
| Dell Children's Medical Center (Ascension Seton) | Austin, TX | $5,967.50 | $73.74 – $89.15 |
| Central Medical Center | Seattle, WA | $6,067.68 | $94.15 – $94.15 |
| HANFORD COMMUNITY HOSPITAL | Selma, CA | $6,365.00 | $98.59 – $255.45 |
| Uchicago Medicine Adventhealth Glenoaks | Glendale Heights, IL | $6,499.79 | $94.45 – $153.00 |
| Uchicago Medicine Adventhealth La Grange | La Grange, IL | $6,499.79 | $92.46 – $153.00 |
| Uchicago Medicine Adventhealth Bolingbrook | Bolingbrook, IL | $6,499.79 | $94.45 – $153.00 |
| CHI Health St. Mary's | Nebraska City, NE | $7,048.66 | $38.28 – $171.55 |
| Sanford Medical Center Mayville | Mayville, ND | $7,445.27 | $61.00 – $226.77 |
| Dickenson Community Hospital | CLINTWOOD, VA | $7,469.88 | $30.45 – $201.74 |
| Lee County Community Hospital | PENNINGTON GAP, VA | $7,469.88 | $30.45 – $201.74 |
| Johnson County Community Hospital | MOUNTAIN CITY, TN | $7,469.88 | $30.45 – $166.23 |
| SAN JOAQUIN COMMUNITY HOSPITAL | Bakersfield, CA | $7,525.00 | $98.59 – $4,006.94 |
| California Hospital Medical Center | Los Angeles, CA | $7,682.89 | $64.48 – $570.38 |
| St. Luke's Health - Brazosport Hospital | Lake Jackson, TX | $7,917.98 | $50.88 – $220.45 |
| Mercy Gilbert Medical Center | Gilbert, AZ | $8,025.26 | $72.96 – $766.92 |
| Mercy General Hospital | Sacramento, CA | $8,127.92 | $76.11 – $280.00 |
| St. John's Camarillo Hospital | Camarillo, CA | $8,148.12 | $44.51 – $197.54 |
| St. Elizabeth Community Hospital | Red Bluff, CA | $8,165.49 | $91.46 – $492.94 |
| CHI St. Vincent North | Sherwood, AR | $8,219.50 | $35.63 – $16,167.38 |
| Morrow County Hospital | Mount Gilead, OH | $8,580.35 | $174.28 – $287.57 |
| LeConte Medical Center | Sevierville, TN | $8,697.57 | $40.61 – $508.85 |
| Chandler Regional Medical Center | Chandler, AZ | $8,742.97 | $72.96 – $836.64 |
| Mercy Hospital Ozark | River Ozark, AR | $8,866.36 | $71.26 – $554.28 |
| St. Joseph's Medical Center Stockton | Stockton, CA | $8,906.15 | $73.84 – $232.88 |
| Sanford Wheaton | Wheaton, MN | $8,973.77 | $86.73 – $322.41 |
| Parkwest Medical Center | Knoxville, TN | $8,997.49 | $40.61 – $269.91 |
| Morristown-Hamblen Hospital Association | Morristown, TN | $8,997.49 | $40.61 – $508.85 |
| Sanford Medical Center Bismarck | Bismarck, ND | $9,173.77 | $55.32 – $108.23 |
Related drugs procedures
- Abatacept (with maltose) 250 mg intravenous solution from $141.66
- Abciximab injection from $354.77
- Abobotulinumtoxina from $51.15
- Acetaminophen 10 mg/ml soln 100 ml glass cont from $3.00
- Acetazolamide 500 mg solution for injection from $6.30
- Acetylcysteine 200 mg/ml (20 %) intravenous solution from $12.60