Alteplase 100 mg infusion from pyxis vial cost at US hospitals
ALTEPLASE 100 MG INFUSION FROM PYXIS VIAL · HCPCS J2997
$556.56
lowest cash price
$15,857.45
national median
$102,964.26
highest cash price
530
hospitals with a published cash price
Middle half of hospitals (25th–75th percentile) against the full range. The same procedure varies $556.56–$102,964.26 — the variation is the story.
Median cash price over time
Sep 1, 2025 ($21,013.50) → Sep 1, 2026 ($21,257.00)
By state
| State | Hospitals | Lowest cash | Median | Highest |
|---|---|---|---|---|
| Alaska | 5 | $960.10 | $19,668.33 | $45,243.16 |
| Arizona | 4 | $8,025.26 | $8,742.97 | $30,343.35 |
| Arkansas | 8 | $8,219.50 | $17,732.73 | $37,806.50 |
| California | 77 | $570.46 | $13,614.60 | $31,630.68 |
| Colorado | 13 | $2,478.25 | $2,478.25 | $2,478.25 |
| Florida | 70 | $556.56 | $1,488.87 | $20,592.84 |
| Georgia | 15 | $2,312.61 | $2,336.68 | $43,507.20 |
| Hawaii | 1 | $19,012.53 | $19,012.53 | $19,012.53 |
| Illinois | 24 | $979.91 | $25,018.70 | $56,853.12 |
| Indiana | 19 | $1,611.20 | $21,257.00 | $87,556.86 |
| Iowa | 20 | $12,850.08 | $25,477.05 | $25,477.05 |
| Kansas | 5 | $1,863.51 | $1,863.51 | $1,863.51 |
| Kentucky | 25 | $748.42 | $32,310.00 | $87,556.86 |
| Louisiana | 4 | $2,559.30 | $2,559.30 | $2,559.30 |
| Maine | 7 | $834.51 | $14,052.42 | $26,765.42 |
| Maryland | 2 | $9,848.40 | $9,848.40 | $9,848.40 |
| Michigan | 15 | $630.01 | $630.01 | $4,598.72 |
| Minnesota | 15 | $4,197.25 | $12,473.57 | $13,925.31 |
| Mississippi | 1 | $10,982.86 | $10,982.86 | $10,982.86 |
| Missouri | 20 | $17,160.70 | $17,217.91 | $21,450.88 |
| Montana | 2 | $21,626.26 | $21,626.26 | $21,626.26 |
| Nebraska | 12 | $3,906.49 | $17,833.94 | $36,092.49 |
| Nevada | 3 | $1,797.84 | $2,600.22 | $3,627.63 |
| New Hampshire | 1 | $31,580.10 | $31,580.10 | $31,580.10 |
| New Jersey | 12 | not published by hospital | not published by hospital | not published by hospital |
| New Mexico | 2 | $1,358.41 | $1,358.41 | $2,819.32 |
| New York | 3 | $28,799.19 | $28,799.19 | $28,799.19 |
| North Carolina | 13 | $705.99 | $17,085.20 | $17,085.20 |
| North Dakota | 3 | $7,445.27 | $9,173.77 | $13,143.43 |
| Ohio | 64 | $8,580.35 | $31,563.16 | $102,964.26 |
| Oklahoma | 13 | $5,084.26 | $5,084.26 | $36,081.48 |
| Oregon | 12 | $806.03 | $23,342.81 | $26,431.24 |
| Pennsylvania | 19 | $612.00 | $5,517.60 | $40,758.00 |
| South Carolina | 11 | $73,130.99 | $73,130.99 | $81,843.35 |
| South Dakota | 5 | $12,473.57 | $12,473.57 | $23,176.60 |
| Tennessee | 26 | $4,048.17 | $8,997.49 | $11,037.54 |
| Texas | 113 | $604.61 | $15,857.45 | $45,243.16 |
| Virginia | 37 | $4,871.66 | $56,498.32 | $92,403.78 |
| Washington | 23 | $635.31 | $12,548.99 | $24,345.24 |
| West Virginia | 8 | $729.05 | $12,124.70 | $32,310.00 |
| Wisconsin | 8 | not published by hospital | not published by hospital | not published by hospital |
All hospitals
| Hospital | Location | Cash price | Negotiated range |
|---|---|---|---|
| Northwestern Medicine Marianjoy Rehabilitation Hospital | Wheaton, IL | $1,845.90 | not published |
| Adventhealth Shawnee Mission | Shawnee Mission, KS | $1,863.51 | $91.48 – $273.90 |
| Adventhealth South Overland Park | Overland Park, KS | $1,863.51 | $91.48 – $273.90 |
| Adventhealth Ottawa | Ottawa, KS | $1,863.51 | $91.48 – $160.56 |
| WHITE MEMORIAL MEDICAL CENTER | MONTEBELLO, CA | $1,880.00 | $70.05 – $1,239.56 |
| Adventhealth Port Charlotte | Port Charlotte, FL | $1,882.36 | not published |
| Adventhealth Zephyrhills | Zephyrhills, FL | $2,100.08 | not published |
| Adventhealth Redmond | Rome, GA | $2,312.61 | $87.57 – $262.56 |
| Adventhealth Murray | Po Box 1406, GA | $2,336.68 | not published |
| Adventhealth Gordon | Calhoun, GA | $2,336.68 | not published |
| Adventhealth Wesley Chapel | Wesley Chapel, FL | $2,454.83 | not published |
| Adventhealth Riverview | Riverview, FL | $2,454.83 | not published |
| AdventHealth Parker | Parker, CO | $2,478.25 | $92.56 – $174.73 |
| AdventHealth Littleton | Littleton, CO | $2,478.25 | $92.56 – $174.73 |
| AdventHealth Avista | Louisville, CO | $2,478.25 | $92.56 – $174.73 |
| AdventHealth Porter | Denver, CO | $2,478.25 | $92.56 – $174.73 |
| AdventHealth Castle Rock | Castle Rock, CO | $2,478.25 | $92.56 – $174.73 |
| Adventhealth Dade City | Dade City, FL | $2,540.37 | not published |
| CHRISTUS St. Francis Cabrini Hospital | Alexandria, LA | $2,559.30 | $85.28 – $96.53 |
| San Martin Hospital | Las Vegas, NV | $2,600.22 | $80.73 – $408.48 |
| Ascension St. Vincent Carmel Ambulatory Surgery Center | Carmel, IN | $2,680.50 | $55.91 – $233.04 |
| Ascension St. Vincent Naab Surgery Center | Indianapolis, IN | $2,680.50 | $55.91 – $233.04 |
| Ascension St. Vincent Fishers (St. Vincent Fishers Hospital, Inc.) | Fishers, IN | $2,680.50 | $55.91 – $233.04 |
| Ascension St. Vincent Evansville (St. Mary's Health, Inc.) | IN 47750|10388 Warrick Wellness Trail Newburgh, IN | $2,680.50 | $54.29 – $233.04 |
| Ascension St. Vincent Kokomo (St. Joseph Hospital & Health Center, Inc.) | Kokomo, IN | $2,680.50 | $55.91 – $233.04 |
| Ascension St. Vincent Carmel (St. Vincent Carmel Hospital, Inc.) | Carmel, IN | $2,680.50 | $55.91 – $233.04 |
| RIDEOUT MEMORIAL HOSPITAL | Marysville, CA | $2,773.16 | $98.59 – $177.46 |
| CHRISTUS St. Vincent Regional Medical Center | Santa Fe, NM | $2,819.32 | $68.44 – $193.08 |
| CHRISTUS Santa Rosa Emergency Center - Alon | San Antonio, TX | $2,845.05 | $85.90 – $171.80 |
| Ascension Seton Smithville (Ascension Seton) | Smithville, TX | $3,069.00 | $73.74 – $89.15 |
| Ascension Seton Edgar B. Davis (Ascension Seton) | Luling, TX | $3,069.00 | $73.74 – $174.86 |
| Ascension Seton Highland Lakes (Ascension Seton) | Burnet, TX | $3,069.00 | $73.74 – $174.86 |
| Adventhealth Ocala | Ocala, FL | $3,135.75 | not published |
| Adventhealth Lake Wales | Lake Wales, FL | $3,207.97 | not published |
| ST HELENA HOSPITAL | Vallejo, CA | $3,564.15 | $69.33 – $255.45 |
| Rose de Lima Hospital | Henderson, NV | $3,627.63 | $80.73 – $408.48 |
| Mercy Medical Center Redding | Redding, CA | $3,760.42 | $57.36 – $386.12 |
| CHI Health Nebraska Heart | Lincoln, NE | $3,906.49 | $42.89 – $146.53 |
| LODI MEMORIAL HOSPITAL ASSOCIATION INC | Lodi, CA | $4,047.29 | $17.52 – $255.45 |
| Hancock County Hospital | SNEEDVILLE, TN | $4,048.17 | $22.41 – $166.23 |
| CHRISTUS Health - West Beaumont | Beaumont, TX | $4,073.26 | $91.46 – $183.26 |
| Sanford Bemidji Medical Center | Bemidji, MN | $4,197.25 | $46.44 – $99.17 |
| St. Bernardine Medical Center | San Bernardino, CA | $4,223.78 | $56.91 – $825.74 |
| CHI Health St. Elizabeth | Lincoln, NE | $4,246.18 | $41.10 – $178.69 |
| Henry Ford St John Hospital | Detroit, MI | $4,598.72 | $38.79 – $100.41 |
| Sequoia Hospital | Redwood City, CA | $4,616.98 | $87.44 – $864.28 |
| Franklin Woods Community Hospital | JOHNSON CITY, TN | $4,871.66 | $30.45 – $204.55 |
| Hawkins County Memorial Hospital | ROGERSVILLE, TN | $4,871.66 | $22.41 – $204.55 |
| Indian Path Community Hospital | KINGSPORT, TN | $4,871.66 | $30.45 – $225.20 |
| Russell County Hospital | LEBANON, VA | $4,871.66 | $30.45 – $204.55 |
Related drugs procedures
- Abatacept (with maltose) 250 mg intravenous solution from $141.66
- Abciximab injection from $354.77
- Abobotulinumtoxina from $51.15
- Acetaminophen 10 mg/ml soln 100 ml glass cont from $3.00
- Acetazolamide 500 mg solution for injection from $6.30
- Acetylcysteine 200 mg/ml (20 %) intravenous solution from $12.60