Alteplase 100 mg infusion from pyxis vial cost at US hospitals
ALTEPLASE 100 MG INFUSION FROM PYXIS VIAL · HCPCS J2997
$556.56
lowest cash price
$15,857.45
national median
$102,964.26
highest cash price
530
hospitals with a published cash price
Middle half of hospitals (25th–75th percentile) against the full range. The same procedure varies $556.56–$102,964.26 — the variation is the story.
Median cash price over time
Sep 1, 2025 ($21,013.50) → Sep 1, 2026 ($21,257.00)
By state
| State | Hospitals | Lowest cash | Median | Highest |
|---|---|---|---|---|
| Alaska | 5 | $960.10 | $19,668.33 | $45,243.16 |
| Arizona | 4 | $8,025.26 | $8,742.97 | $30,343.35 |
| Arkansas | 8 | $8,219.50 | $17,732.73 | $37,806.50 |
| California | 77 | $570.46 | $13,614.60 | $31,630.68 |
| Colorado | 13 | $2,478.25 | $2,478.25 | $2,478.25 |
| Florida | 70 | $556.56 | $1,488.87 | $20,592.84 |
| Georgia | 15 | $2,312.61 | $2,336.68 | $43,507.20 |
| Hawaii | 1 | $19,012.53 | $19,012.53 | $19,012.53 |
| Illinois | 24 | $979.91 | $25,018.70 | $56,853.12 |
| Indiana | 19 | $1,611.20 | $21,257.00 | $87,556.86 |
| Iowa | 20 | $12,850.08 | $25,477.05 | $25,477.05 |
| Kansas | 5 | $1,863.51 | $1,863.51 | $1,863.51 |
| Kentucky | 25 | $748.42 | $32,310.00 | $87,556.86 |
| Louisiana | 4 | $2,559.30 | $2,559.30 | $2,559.30 |
| Maine | 7 | $834.51 | $14,052.42 | $26,765.42 |
| Maryland | 2 | $9,848.40 | $9,848.40 | $9,848.40 |
| Michigan | 15 | $630.01 | $630.01 | $4,598.72 |
| Minnesota | 15 | $4,197.25 | $12,473.57 | $13,925.31 |
| Mississippi | 1 | $10,982.86 | $10,982.86 | $10,982.86 |
| Missouri | 20 | $17,160.70 | $17,217.91 | $21,450.88 |
| Montana | 2 | $21,626.26 | $21,626.26 | $21,626.26 |
| Nebraska | 12 | $3,906.49 | $17,833.94 | $36,092.49 |
| Nevada | 3 | $1,797.84 | $2,600.22 | $3,627.63 |
| New Hampshire | 1 | $31,580.10 | $31,580.10 | $31,580.10 |
| New Jersey | 12 | not published by hospital | not published by hospital | not published by hospital |
| New Mexico | 2 | $1,358.41 | $1,358.41 | $2,819.32 |
| New York | 3 | $28,799.19 | $28,799.19 | $28,799.19 |
| North Carolina | 13 | $705.99 | $17,085.20 | $17,085.20 |
| North Dakota | 3 | $7,445.27 | $9,173.77 | $13,143.43 |
| Ohio | 64 | $8,580.35 | $31,563.16 | $102,964.26 |
| Oklahoma | 13 | $5,084.26 | $5,084.26 | $36,081.48 |
| Oregon | 12 | $806.03 | $23,342.81 | $26,431.24 |
| Pennsylvania | 19 | $612.00 | $5,517.60 | $40,758.00 |
| South Carolina | 11 | $73,130.99 | $73,130.99 | $81,843.35 |
| South Dakota | 5 | $12,473.57 | $12,473.57 | $23,176.60 |
| Tennessee | 26 | $4,048.17 | $8,997.49 | $11,037.54 |
| Texas | 113 | $604.61 | $15,857.45 | $45,243.16 |
| Virginia | 37 | $4,871.66 | $56,498.32 | $92,403.78 |
| Washington | 23 | $635.31 | $12,548.99 | $24,345.24 |
| West Virginia | 8 | $729.05 | $12,124.70 | $32,310.00 |
| Wisconsin | 8 | not published by hospital | not published by hospital | not published by hospital |
All hospitals
| Hospital | Location | Cash price | Negotiated range |
|---|---|---|---|
| Dominican Hospital | Santa Cruz, CA | $9,512.83 | $61.23 – $593.92 |
| Cumberland Medical Center, Inc. | Crossville, TN | $9,597.32 | $48.73 – $508.85 |
| Mercy Medical Center Merced | Merced, CA | $9,600.63 | $47.83 – $320.54 |
| Lonesome Pine Hospital | BIG STONE GAP, VA | $9,743.32 | $22.41 – $225.20 |
| UPMC Western Maryland | Cumberland, MD | $9,848.40 | $318.00 – $318.00 |
| Roane County Medical Center | Harriman, TN | $9,897.23 | $40.61 – $269.91 |
| Fort Loudoun Medical Center | Lenoir City, TN | $9,897.23 | $40.61 – $269.91 |
| Fort Sanders Regional Medical Center | Knoxville, TN | $9,897.23 | $40.61 – $508.85 |
| Methodist Medical Center of Oak Ridge | Oak Ridge, TN | $9,897.23 | $40.61 – $269.91 |
| WellSpan Chambersburg Hospital | Chambersburg, PA | $10,011.40 | $102.47 – $840.24 |
| Woodland Memorial Hospital | Woodland, CA | $10,215.82 | $38.50 – $350.00 |
| Mercy San Juan Medical Center | Carmichael, CA | $10,215.82 | $38.50 – $290.50 |
| Methodist Hospital of Sacramento | Sacramento, CA | $10,737.80 | $86.30 – $290.50 |
| Mid Coast Hospital | Brunswick, ME | $10,872.85 | $88.97 – $595.55 |
| 39-3714515 BMH Oktibbeha County | STARKVILLE, MS | $10,982.86 | $65.31 – $217.24 |
| Bristol Regional Medical Center | BRISTOL, TN | $11,037.54 | $26.89 – $225.20 |
| Greeneville Community Hospital | GREENEVILLE, TN | $11,037.54 | $16.14 – $204.55 |
| Holston Valley Medical Center | KINGSPORT, TN | $11,037.54 | $26.89 – $225.20 |
| Johnson City Medical Center | JOHNSON CITY, TN | $11,037.54 | $30.45 – $204.55 |
| Johnston Memorial Hospital | ABINGDON, VA | $11,037.54 | $30.45 – $204.55 |
| Methodist Charlton Medical Center | Dallas, TX | $11,088.50 | $93.83 – $253.35 |
| Methodist Mansfield Medical Center | Mansfield, TX | $11,088.50 | $93.83 – $253.35 |
| Methodist Southlake Medical Center | Souhtlake, TX | $11,088.50 | $91.48 – $331.70 |
| Sanford Thief River Falls Medical Center | Thief River Falls, MN | $11,385.60 | $192.44 – $504.21 |
| Sanford Behavioral Health Thief River Falls | Thief River Falls, MN | $11,385.60 | $192.44 – $504.21 |
| Providence Holy Family Hospital | Spokane, WA | $11,522.62 | $88.97 – $201.26 |
| Providence Sacred Heart Medical Center and Children's Hospital | Spokane, WA | $11,522.62 | $69.40 – $200.45 |
| St. Clare Hospital | Lakewood, WA | $11,838.49 | $60.30 – $262.66 |
| Abbott Northwestern Hospital | MN 55407, MN | $11,935.98 | $80.40 – $273.53 |
| Mercy Hospital | MN 55443 | 550 Osborne Road NE. Fridley, MN | $11,935.98 | $80.40 – $146.47 |
| United Hospital | MN | 1175 Nininger Road. Hastings, MN | $11,935.98 | $80.40 – $148.43 |
| Summersville Regional Medical Center | Summersville, WV | $12,124.70 | $146.80 – $146.80 |
| PORTLAND ADVENTIST MEDICAL CENTER | Portland, OR | $12,393.46 | $76.07 – $2,025.98 |
| Providence St Mary Medical Center | Walla Walla, WA | $12,398.11 | $91.34 – $564.83 |
| Sanford Clear Lake Medical Center | Clear Lake, SD | $12,473.57 | $164.03 – $287.77 |
| Sanford Westbrook Hospital | Westbrook, MN | $12,473.57 | $3,774.81 – $14,032.76 |
| Sanford Vermillion Hospital | Vermillion, SD | $12,473.57 | $118.30 – $360.90 |
| St. Anthony Hospital | Gig Harbor, WA | $12,491.85 | $60.30 – $262.66 |
| St. Anne Hospital | Burien, WA | $12,541.42 | $51.86 – $108.54 |
| Swedish Medical Center Cherry Hill | Seattle, WA | $12,548.99 | $91.34 – $175.92 |
| Swedish Medical Center - First Hill Campus | Seattle, WA | $12,548.99 | $91.34 – $240.55 |
| Swedish Issaquah | Issaquah, WA | $12,548.99 | $91.34 – $240.55 |
| Swedish Edmonds Hospital | Edmonds, WA | $12,548.99 | $95.09 – $187.38 |
| Sanford Chamberlain Medical Center | Chamberlain, SD | $12,850.08 | $109.35 – $287.77 |
| Sanford Sheldon Medical Center | Sheldon, IA | $12,850.08 | $91.13 – $287.77 |
| St. Francis Hospital | Federal Way, WA | $12,889.19 | $60.30 – $262.66 |
| Trinity Medical Center East | Steubenville, OH | $12,949.24 | $91.48 – $174.79 |
| New Ulm Medical Center | MN 56073, MN | $12,958.26 | $89.14 – $650.91 |
| SONORA COMMUNITY HOSPITAL | Sonora, CA | $13,090.00 | $66.29 – $206.43 |
| Sanford Fargo Medical Center | Fargo, ND | $13,143.43 | $89.16 – $405.95 |
Related drugs procedures
- Abatacept (with maltose) 250 mg intravenous solution from $141.66
- Abciximab injection from $354.77
- Abobotulinumtoxina from $51.15
- Acetaminophen 10 mg/ml soln 100 ml glass cont from $3.00
- Acetazolamide 500 mg solution for injection from $6.30
- Acetylcysteine 200 mg/ml (20 %) intravenous solution from $12.60