Alteplase 100 mg infusion from pyxis vial cost at US hospitals
ALTEPLASE 100 MG INFUSION FROM PYXIS VIAL · HCPCS J2997
$556.56
lowest cash price
$15,857.45
national median
$102,964.26
highest cash price
530
hospitals with a published cash price
Middle half of hospitals (25th–75th percentile) against the full range. The same procedure varies $556.56–$102,964.26 — the variation is the story.
Median cash price over time
Sep 1, 2025 ($21,013.50) → Sep 1, 2026 ($21,257.00)
By state
| State | Hospitals | Lowest cash | Median | Highest |
|---|---|---|---|---|
| Alaska | 5 | $960.10 | $19,668.33 | $45,243.16 |
| Arizona | 4 | $8,025.26 | $8,742.97 | $30,343.35 |
| Arkansas | 8 | $8,219.50 | $17,732.73 | $37,806.50 |
| California | 77 | $570.46 | $13,614.60 | $31,630.68 |
| Colorado | 13 | $2,478.25 | $2,478.25 | $2,478.25 |
| Florida | 70 | $556.56 | $1,488.87 | $20,592.84 |
| Georgia | 15 | $2,312.61 | $2,336.68 | $43,507.20 |
| Hawaii | 1 | $19,012.53 | $19,012.53 | $19,012.53 |
| Illinois | 24 | $979.91 | $25,018.70 | $56,853.12 |
| Indiana | 19 | $1,611.20 | $21,257.00 | $87,556.86 |
| Iowa | 20 | $12,850.08 | $25,477.05 | $25,477.05 |
| Kansas | 5 | $1,863.51 | $1,863.51 | $1,863.51 |
| Kentucky | 25 | $748.42 | $32,310.00 | $87,556.86 |
| Louisiana | 4 | $2,559.30 | $2,559.30 | $2,559.30 |
| Maine | 7 | $834.51 | $14,052.42 | $26,765.42 |
| Maryland | 2 | $9,848.40 | $9,848.40 | $9,848.40 |
| Michigan | 15 | $630.01 | $630.01 | $4,598.72 |
| Minnesota | 15 | $4,197.25 | $12,473.57 | $13,925.31 |
| Mississippi | 1 | $10,982.86 | $10,982.86 | $10,982.86 |
| Missouri | 20 | $17,160.70 | $17,217.91 | $21,450.88 |
| Montana | 2 | $21,626.26 | $21,626.26 | $21,626.26 |
| Nebraska | 12 | $3,906.49 | $17,833.94 | $36,092.49 |
| Nevada | 3 | $1,797.84 | $2,600.22 | $3,627.63 |
| New Hampshire | 1 | $31,580.10 | $31,580.10 | $31,580.10 |
| New Jersey | 12 | not published by hospital | not published by hospital | not published by hospital |
| New Mexico | 2 | $1,358.41 | $1,358.41 | $2,819.32 |
| New York | 3 | $28,799.19 | $28,799.19 | $28,799.19 |
| North Carolina | 13 | $705.99 | $17,085.20 | $17,085.20 |
| North Dakota | 3 | $7,445.27 | $9,173.77 | $13,143.43 |
| Ohio | 64 | $8,580.35 | $31,563.16 | $102,964.26 |
| Oklahoma | 13 | $5,084.26 | $5,084.26 | $36,081.48 |
| Oregon | 12 | $806.03 | $23,342.81 | $26,431.24 |
| Pennsylvania | 19 | $612.00 | $5,517.60 | $40,758.00 |
| South Carolina | 11 | $73,130.99 | $73,130.99 | $81,843.35 |
| South Dakota | 5 | $12,473.57 | $12,473.57 | $23,176.60 |
| Tennessee | 26 | $4,048.17 | $8,997.49 | $11,037.54 |
| Texas | 113 | $604.61 | $15,857.45 | $45,243.16 |
| Virginia | 37 | $4,871.66 | $56,498.32 | $92,403.78 |
| Washington | 23 | $635.31 | $12,548.99 | $24,345.24 |
| West Virginia | 8 | $729.05 | $12,124.70 | $32,310.00 |
| Wisconsin | 8 | not published by hospital | not published by hospital | not published by hospital |
All hospitals
| Hospital | Location | Cash price | Negotiated range |
|---|---|---|---|
| Boca Raton Regional Hospital | BOCA RATON, FL | $556.56 | $3.60 – $71.82 |
| Providence Mission Hospital - Mission Viejo | Mission Viejo, CA | $570.46 | $55.14 – $196.64 |
| Texas Health Hospital Mansfield | Mansfield, TX | $604.61 | $76.17 – $197.17 |
| Texas Health Huguley Hospital Fort Worth South | Burleson, TX | $604.61 | $76.17 – $197.17 |
| UPMC Mercy | Pittsburgh, PA | $612.00 | $48.57 – $204.13 |
| Henry Ford Warren Hospital | Warren, MI | $630.01 | $38.79 – $100.41 |
| Providence Regional Medical Center Everett - Colby Campus | Everett, WA | $635.31 | $75.63 – $204.81 |
| AdventHealth New Smyrna Beach | New Smyrna Beach, FL | $646.15 | not published |
| AdventHealth Polk | Columbus, NC | $705.99 | not published |
| Berkeley Medical Center | Martinsburg, WV | $729.05 | $98.59 – $172.53 |
| Princeton Community Hospital | Princeton, WV | $729.05 | $98.59 – $574.25 |
| Thomas Hospitals | South Charleston, WV | $729.05 | $98.59 – $498.95 |
| Baptist Hospital | MIAMI, FL | $737.75 | $67.64 – $742.50 |
| Bethesda Hospital East | BOYNTON BEACH, FL | $737.75 | $67.64 – $742.50 |
| Doctors Hospital | CORAL GABLES, FL | $737.75 | $65.57 – $742.50 |
| Baptist Health Hospital Doral | SOUTH MIAMI, FL | $737.75 | $65.57 – $742.50 |
| Homestead Hospital | HOMESTEAD, FL | $737.75 | $65.57 – $742.50 |
| West Kendall Baptist Hospital | MIAMI, FL | $737.75 | $65.57 – $742.50 |
| Adventhealth Manchester | Manchester, KY | $748.42 | not published |
| Adventhealth Rollins Brook | Lampasas, TX | $766.25 | $144.95 – $144.95 |
| Adventhealth Central Texas | Killeen, TX | $766.25 | $94.45 – $151.12 |
| Providence Hood River Memorial Hospital | Hood River, OR | $806.03 | not published |
| Fishermens Community Hospital | MARATHON, FL | $814.45 | $65.57 – $844.20 |
| Mariners Hospital | TAVERNIER, FL | $814.45 | $65.57 – $844.20 |
| Stephens Memorial Hospital | Norway, ME | $834.51 | $88.97 – $784.44 |
| HCA FLORIDA WOODMONT HOSPITAL | TAMARAC, FL | $948.75 | $92.24 – $156.90 |
| Providence Seward Hospital | Seward, AK | $960.10 | not published |
| HSHS St. Anthony's Memorial Hospital | Mattoon, IL | $979.91 | $88.23 – $420.76 |
| WellSpan Gettysburg Hospital | Gettysburg, PA | $1,077.00 | $111.38 – $640.22 |
| Adventhealth Tampa | Tampa, FL | $1,128.27 | not published |
| Adventhealth Waterman | Tavares, FL | $1,145.18 | not published |
| WellSpan Surgery & Rehabilitation Hospital | York PA 17403, PA | $1,223.20 | $111.38 – $640.22 |
| Adventhealth Carrollwood | Tampa, FL | $1,243.28 | not published |
| Covenant Children's Hospital | Lubbock, TX | $1,358.41 | $140.81 – $338.09 |
| Covenant Health Hobbs Hospital | Hobbs, NM | $1,358.41 | not published |
| Covenant Specialty Hospital | Lubbock, TX | $1,358.41 | not published |
| Adventhealth North Pinellas | Tarpon Springs, FL | $1,488.87 | not published |
| St. Joseph Health Grimes Hospital | Navasota, TX | $1,501.57 | $25.00 – $163.23 |
| St. Joseph Health Burleson Hospital | Caldwell, TX | $1,501.57 | $25.00 – $132.35 |
| St. Joseph Health Madison Hospital | Madisonville, TX | $1,501.57 | $18.74 – $132.35 |
| St. Joseph Health College Station Hospital | College Station, TX | $1,501.57 | $25.00 – $125.00 |
| Providence St Luke's Rehabilitation Medical Center | Spokane, WA | $1,536.68 | $95.09 – $104.60 |
| Adventhealth Connerton | Land O Lakes, FL | $1,540.71 | not published |
| Adventhealth Sebring | Sebring, FL | $1,583.73 | not published |
| Adventhealth Wauchula | Wauchula, FL | $1,583.73 | not published |
| Ascension St. Vincent Seton (St. Vincent Seton Specialty Hospital, Inc.) | Indianapolis, IN | $1,611.20 | $55.91 – $233.04 |
| Ascension St. Vincent Anderson (St. Vincent Anderson Regional Hospital, Inc.) | Anderson, IN | $1,611.20 | $55.91 – $233.04 |
| Ascension St. Vincent Heart Center (St. Vincent Heart Center of Indiana, LLC) | Carmel, IN | $1,611.20 | $55.91 – $233.04 |
| AdventHealth Orlando | Orlando, FL | $1,737.73 | not published |
| Siena Hospital | Henderson, NV | $1,797.84 | $80.73 – $408.48 |
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- Acetaminophen 10 mg/ml soln 100 ml glass cont from $3.00
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- Acetylcysteine 200 mg/ml (20 %) intravenous solution from $12.60