Alpha-1-proteinase inhibitor (human) 1,000 mg (+/-) IV solution cost at US hospitals
ALPHA-1-PROTEINASE INHIBITOR (HUMAN) 1,000 MG (+/-) IV SOLUTION · HCPCS J0256
$3.25
lowest cash price
$13.14
national median
$378.00
highest cash price
218
hospitals with a published cash price
Middle half of hospitals (25th–75th percentile) against the full range. The same procedure varies $3.25–$378.00 — the variation is the story.
Median cash price over time
Sep 1, 2025 ($71.68) → Sep 1, 2026 ($4.94)
By state
| State | Hospitals | Lowest cash | Median | Highest |
|---|---|---|---|---|
| Alaska | 1 | not published by hospital | not published by hospital | not published by hospital |
| Arizona | 1 | $7.26 | $7.26 | $7.26 |
| California | 52 | $3.98 | $4.28 | $19.69 |
| Colorado | 11 | $53.00 | $53.00 | $135.53 |
| Florida | 53 | $3.25 | $3.25 | $49.75 |
| Georgia | 19 | $13.53 | $13.53 | $13.53 |
| Hawaii | 1 | $5.74 | $5.74 | $5.74 |
| Illinois | 27 | $9.62 | $38.29 | $279.81 |
| Iowa | 18 | $9.56 | $9.76 | $48.76 |
| Kansas | 5 | not published by hospital | not published by hospital | not published by hospital |
| Kentucky | 10 | $3.60 | $114.82 | $157.78 |
| Louisiana | 6 | not published by hospital | not published by hospital | not published by hospital |
| Maine | 3 | $71.68 | $71.68 | $71.68 |
| Maryland | 1 | not published by hospital | not published by hospital | not published by hospital |
| Michigan | 17 | $7.41 | $7.41 | $7.41 |
| Minnesota | 8 | not published by hospital | not published by hospital | not published by hospital |
| Missouri | 14 | not published by hospital | not published by hospital | not published by hospital |
| Montana | 1 | not published by hospital | not published by hospital | not published by hospital |
| Nebraska | 7 | $41.79 | $41.79 | $84.58 |
| New Jersey | 21 | $4.94 | $5.19 | $5.19 |
| New Mexico | 2 | not published by hospital | not published by hospital | not published by hospital |
| New York | 19 | $4.94 | $4.94 | $36.00 |
| North Carolina | 13 | $22.78 | $22.78 | $22.78 |
| North Dakota | 2 | not published by hospital | not published by hospital | not published by hospital |
| Ohio | 29 | $10.15 | $10.15 | $10.15 |
| Oklahoma | 8 | $13.14 | $13.14 | $13.14 |
| Oregon | 4 | $6.51 | $6.51 | $6.51 |
| Pennsylvania | 21 | $29.80 | $51.00 | $378.00 |
| South Carolina | 8 | not published by hospital | not published by hospital | not published by hospital |
| South Dakota | 5 | not published by hospital | not published by hospital | not published by hospital |
| Tennessee | 9 | not published by hospital | not published by hospital | not published by hospital |
| Texas | 82 | $5.52 | $18.72 | $26.25 |
| Virginia | 21 | not published by hospital | not published by hospital | not published by hospital |
| Washington | 12 | $7.36 | $7.45 | $10.46 |
| West Virginia | 1 | $3.60 | $3.60 | $3.60 |
| Wisconsin | 23 | $6.53 | $9.62 | $17.07 |
All hospitals
| Hospital | Location | Cash price | Negotiated range |
|---|---|---|---|
| Sanford Luverne Medical Center | Luverne, MN | not published | $5.03 – $5.03 |
| Sanford Wheaton | Wheaton, MN | not published | $5.03 – $5.03 |
| Providence St Joseph Hospital Eureka | Eureka, CA | not published | $4.01 – $11.09 |
| Queen of The Valley Medical Center | Napa, CA | not published | $3.36 – $11.09 |
| SSM Health St. Joseph Hospital - St. Charles | Saint Charles, MO | not published | $0.61 – $8.55 |
| Clara Maass Medical Center | Belleville, NJ | not published | $4.59 – $11.36 |
| Community Medical Center | Toms River, NJ | not published | $4.59 – $11.06 |
| Sanford Bagley Medical Center | Bagley, MN | not published | $5.03 – $5.03 |
| Sanford Westbrook Hospital | Westbrook, MN | not published | $5.03 – $5.03 |
| Sanford Canby Medical Center | Canby, MN | not published | $5.03 – $5.03 |
| Covenant Hospital Plainview | Plainview, TX | not published | $4.99 – $5.42 |
| Providence Little Company of Mary Med Center Torrance | Torrance, CA | not published | $5.14 – $11.09 |
| Southeastern Medical Center | Cambridge, OH | not published | $5.46 – $33.09 |
| Grant Medical Center | Columbus, OH | not published | $5.46 – $13.79 |
| Berger Hospital | Circleville, OH | not published | $5.46 – $33.09 |
| Providence Little Co of Mary Med Center San Pedro | San Pedro, CA | not published | $5.14 – $11.09 |
| SSM Health St. Mary's Hospital - Madison | Madison, WI | not published | $3.85 – $9.85 |
| Advocate Good Samaritan Hospital | Downers Grove, IL | not published | $7.52 – $16.33 |
| Providence St Luke's Rehabilitation Medical Center | Spokane, WA | not published | $5.14 – $5.66 |
| UnityPoint Health - Grinnell Regional Medical Center | Grinnell, IA | not published | $4.83 – $6.35 |
| Providence Holy Cross Medical Center | Mission Hills, CA | not published | $5.14 – $11.09 |
| SSM Health St. Anthony Hospital - Midwest | Midwest City, OK | not published | $5.13 – $10.01 |
| Advocate Condell Medical Center | Libertyville, IL | not published | $5.27 – $12.80 |
| HCA FLORIDA LARGO HOSPITAL | LARGO, FL | not published | $4.99 – $11.05 |
| Adventhealth Ottawa | Ottawa, KS | not published | $5.09 – $9.28 |
| MEDICAL CITY ARLINGTON HOSPITAL | RED OAK, TX | not published | $4.99 – $31.40 |
| Trinitas Regional Medical Center | Elizabeth, NJ | not published | $0.01 – $11.06 |
| Wellstar Windy Hill Hospital | Marietta, GA | not published | $4.93 – $12.03 |
| Stephens Memorial Hospital | Norway, ME | not published | $4.83 – $10.06 |
| Garrett Regional Medical Center | Oakland, MD | not published | not published |
| MEDICAL CITY WEATHERFORD HOSPITAL | Weatherford, TX | not published | $5.16 – $31.91 |
| RESEARCH MEDICAL CENTER | Kansas City, MO | not published | $5.14 – $8.48 |
| OSF Little Company of Mary Medical Center | Evergreen Park, IL | not published | $5.14 – $9.56 |
| OSF Sacred Heart Medical Center – Urbana | Danville, IL | not published | $5.14 – $6.30 |
| Sentara Norfolk General Hospital | Norfolk, VA | not published | $5.57 – $5.73 |
| Sentara Northern Virginia Medical Center | Woodbridge, VA | not published | $5.57 – $6.61 |
| MEDICAL CITY MCKINNEY HOSPITAL | McKinney, TX | not published | $5.01 – $31.40 |
| Sentara Williamsburg Regional Medical Center | Williamsburg, VA | not published | $5.57 – $5.73 |
| Sentara CarePlex Hospital | Hampton, VA | not published | $5.57 – $5.73 |
| AdventHealth Littleton | Littleton, CO | not published | $0.92 – $10.10 |
| Wellstar West Georgia Medical Center | Lagrange, GA | not published | $5.46 – $12.03 |
| Wellstar Sylvan Grove Hospital | Jackson, GA | not published | $9.70 – $16.88 |
| Wellstar Spalding Regional Hospital | Griffin, GA | not published | $5.46 – $12.03 |
| Wellstar Paulding Hospital | Hiram, GA | not published | $5.46 – $12.03 |
| Wellstar North Fulton Hospital | Roswell, GA | not published | $5.46 – $12.03 |
| Sentara Obici Hospital | Suffolk, VA | not published | $5.57 – $5.73 |
| Corewell Health Wayne | Wayne, MI | not published | $3.28 – $7.37 |
| Corewell Health Troy | Troy, MI | not published | $3.28 – $7.37 |
| Corewell Health Trenton | Trenton, MI | not published | $3.28 – $7.37 |
| Sentara Princess Anne Hospital | Virginia Beach, VA | not published | $5.57 – $5.73 |
Related drugs procedures
- Abatacept (with maltose) 250 mg intravenous solution from $141.66
- Abciximab injection from $354.77
- Abobotulinumtoxina from $51.15
- Acetaminophen 10 mg/ml soln 100 ml glass cont from $3.00
- Acetazolamide 500 mg solution for injection from $6.30
- Acetylcysteine 200 mg/ml (20 %) intravenous solution from $12.60