Alpha-1-proteinase inhibitor (human) 1,000 mg (+/-) IV solution cost at US hospitals
ALPHA-1-PROTEINASE INHIBITOR (HUMAN) 1,000 MG (+/-) IV SOLUTION · HCPCS J0256
$3.25
lowest cash price
$13.14
national median
$378.00
highest cash price
218
hospitals with a published cash price
Middle half of hospitals (25th–75th percentile) against the full range. The same procedure varies $3.25–$378.00 — the variation is the story.
Median cash price over time
Sep 1, 2025 ($71.68) → Sep 1, 2026 ($4.94)
By state
| State | Hospitals | Lowest cash | Median | Highest |
|---|---|---|---|---|
| Alaska | 1 | not published by hospital | not published by hospital | not published by hospital |
| Arizona | 1 | $7.26 | $7.26 | $7.26 |
| California | 52 | $3.98 | $4.28 | $19.69 |
| Colorado | 11 | $53.00 | $53.00 | $135.53 |
| Florida | 53 | $3.25 | $3.25 | $49.75 |
| Georgia | 19 | $13.53 | $13.53 | $13.53 |
| Hawaii | 1 | $5.74 | $5.74 | $5.74 |
| Illinois | 27 | $9.62 | $38.29 | $279.81 |
| Iowa | 18 | $9.56 | $9.76 | $48.76 |
| Kansas | 5 | not published by hospital | not published by hospital | not published by hospital |
| Kentucky | 10 | $3.60 | $114.82 | $157.78 |
| Louisiana | 6 | not published by hospital | not published by hospital | not published by hospital |
| Maine | 3 | $71.68 | $71.68 | $71.68 |
| Maryland | 1 | not published by hospital | not published by hospital | not published by hospital |
| Michigan | 17 | $7.41 | $7.41 | $7.41 |
| Minnesota | 8 | not published by hospital | not published by hospital | not published by hospital |
| Missouri | 14 | not published by hospital | not published by hospital | not published by hospital |
| Montana | 1 | not published by hospital | not published by hospital | not published by hospital |
| Nebraska | 7 | $41.79 | $41.79 | $84.58 |
| New Jersey | 21 | $4.94 | $5.19 | $5.19 |
| New Mexico | 2 | not published by hospital | not published by hospital | not published by hospital |
| New York | 19 | $4.94 | $4.94 | $36.00 |
| North Carolina | 13 | $22.78 | $22.78 | $22.78 |
| North Dakota | 2 | not published by hospital | not published by hospital | not published by hospital |
| Ohio | 29 | $10.15 | $10.15 | $10.15 |
| Oklahoma | 8 | $13.14 | $13.14 | $13.14 |
| Oregon | 4 | $6.51 | $6.51 | $6.51 |
| Pennsylvania | 21 | $29.80 | $51.00 | $378.00 |
| South Carolina | 8 | not published by hospital | not published by hospital | not published by hospital |
| South Dakota | 5 | not published by hospital | not published by hospital | not published by hospital |
| Tennessee | 9 | not published by hospital | not published by hospital | not published by hospital |
| Texas | 82 | $5.52 | $18.72 | $26.25 |
| Virginia | 21 | not published by hospital | not published by hospital | not published by hospital |
| Washington | 12 | $7.36 | $7.45 | $10.46 |
| West Virginia | 1 | $3.60 | $3.60 | $3.60 |
| Wisconsin | 23 | $6.53 | $9.62 | $17.07 |
All hospitals
| Hospital | Location | Cash price | Negotiated range |
|---|---|---|---|
| Corewell Health Taylor | Taylor, MI | not published | $3.28 – $7.37 |
| Corewell Health Gross Pointe | Grosse Pointe, MI | not published | $3.28 – $7.37 |
| Corewell Health Zeeland | Zeeland, MI | not published | $5.38 – $9.82 |
| Corewell Health Greenville | Greenville, MI | not published | $5.38 – $9.82 |
| Sentara Virginia Beach General Hospital | Virginia Beach, VA | not published | $5.57 – $5.73 |
| Sentara Leigh Hospital | Norfolk, VA | not published | $5.57 – $5.73 |
| Sentara Halifax Regional Hospital | South Boston, VA | not published | $5.24 – $5.40 |
| Corewell Health Reed City | Po Box 75, MI | not published | $5.38 – $5.38 |
| Sentara RMH Medical Center | Harrisonburg, VA | not published | $5.57 – $5.73 |
| Sentara Martha Jefferson Hospital | Charlottesville, VA | not published | $5.57 – $5.73 |
| Corewell Health Blodgett Hospital | East Grand Rapids, MI | not published | $5.38 – $9.82 |
| Aurora West Allis Medical Center | West Allis, WI | not published | $4.94 – $12.42 |
| Aurora Medical Center Washington County | Hartford, WI | not published | $4.94 – $12.42 |
| Aurora Medical Center Summit | Summit, WI | not published | $4.94 – $12.42 |
| Aurora Sinai Medical Center of Aurora Health Care Metro | Milwaukee, WI | not published | $4.94 – $12.42 |
| Aurora Psychiatric Hospital | Wauwatosa, WI | not published | $4.94 – $12.42 |
| Aurora Medical Center Fond du Lac | Fond Du Lac, WI | not published | $4.94 – $12.42 |
| Aurora Medical Center Kenosha | Kenosha, WI | not published | $4.94 – $12.42 |
| Aurora Medical Center Manitowoc | Two Rivers, WI | not published | $4.94 – $12.42 |
| Aurora Medical Center Grafton | Grafton, WI | not published | $4.94 – $12.42 |
| Aurora Medical Center Burlington | Burlington, WI | not published | $4.94 – $12.42 |
| St Elias Specialty Hospital | Anchorage, AK | not published | $4.99 – $20.23 |
| Covenant Medical Center | Lubbock, TX | not published | $5.14 – $20.23 |
| Aurora Baycare Medical Center | Green Bay, WI | not published | $4.94 – $12.42 |
| Robert Wood Johnson University Hospital Rahway | Rahway, NJ | not published | $4.59 – $11.06 |
| Corewell Health Butterworth Hospital | Grand Rapids, MI | not published | $5.38 – $9.82 |
| Dublin Methodist Hospital | Dublin, OH | not published | $5.46 – $13.79 |
| Corewell Health Gerber | Fremont, MI | not published | $5.38 – $5.38 |
| Corewell Health Big Rapids | Big Rapids, MI | not published | $5.38 – $9.82 |
| Sanford Clear Lake Medical Center | Clear Lake, SD | not published | $5.03 – $5.03 |
| SSM Health St. Mary's Hospital - Janesville | Janesville, WI | not published | $3.85 – $9.85 |
| SSM Health St. Clare Hospital - Baraboo | Baraboo, WI | not published | $3.85 – $9.85 |
| Wellstar MCG Health | Augusta, GA | not published | $5.46 – $10.70 |
| Wellstar Kennestone Hospital | Marietta, GA | not published | $5.46 – $12.03 |
| CHRISTUS Children's Hospital | San Antonio, TX | not published | $13.39 – $13.39 |
| Wellstar Douglas Hospital | Douglasville, GA | not published | $5.46 – $12.03 |
| Wellstar Cobb Hospital | Austell, GA | not published | $5.46 – $12.03 |
| SSM Health St. Anthony Hospital - Oklahoma City | Oklahoma City, OK | not published | $5.13 – $10.01 |
| Adventhealth Rollins Brook | Lampasas, TX | not published | $17.90 – $17.90 |
| CHRISTUS St. Vincent Regional Medical Center | Santa Fe, NM | not published | $4.33 – $10.74 |
| CHRISTUS St. Francis Cabrini Hospital | Alexandria, LA | not published | $4.74 – $5.32 |
| CHRISTUS Shreveport-Bossier Health System-Highland | Shreveport, LA | not published | $4.71 – $5.29 |
| CHRISTUS Ochsner Lake Area Hospital | Lake Charles, LA | not published | $4.54 – $5.09 |
| CHRISTUS Ochsner St. Patrick Hospital | Lake Charles, LA | not published | $4.61 – $5.17 |
| CHRISTUS Louisiana Surgical Hospital | Alexandria, LA | not published | $4.84 – $12.98 |
| CHRISTUS Coushatta Health Care Center | Coushatta, LA | not published | $4.99 – $5.12 |
| SSM Health Cardinal Glennon Children's Hospital | Saint Louis, MO | not published | $0.60 – $10.12 |
| AdventHealth Parker | Parker, CO | not published | $0.92 – $10.10 |
| HCA FLORIDA PASADENA HOSPITAL | South Pasadena, FL | not published | $5.01 – $11.55 |
| Providence St Vincent Medical Center | Portland, OR | not published | $5.06 – $10.28 |
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