Alpha-1-proteinase inhibitor (human) 1,000 mg (+/-) IV solution cost at US hospitals
ALPHA-1-PROTEINASE INHIBITOR (HUMAN) 1,000 MG (+/-) IV SOLUTION · HCPCS J0256
$3.25
lowest cash price
$13.14
national median
$378.00
highest cash price
218
hospitals with a published cash price
Middle half of hospitals (25th–75th percentile) against the full range. The same procedure varies $3.25–$378.00 — the variation is the story.
Median cash price over time
Sep 1, 2025 ($71.68) → Sep 1, 2026 ($4.94)
By state
| State | Hospitals | Lowest cash | Median | Highest |
|---|---|---|---|---|
| Alaska | 1 | not published by hospital | not published by hospital | not published by hospital |
| Arizona | 1 | $7.26 | $7.26 | $7.26 |
| California | 52 | $3.98 | $4.28 | $19.69 |
| Colorado | 11 | $53.00 | $53.00 | $135.53 |
| Florida | 53 | $3.25 | $3.25 | $49.75 |
| Georgia | 19 | $13.53 | $13.53 | $13.53 |
| Hawaii | 1 | $5.74 | $5.74 | $5.74 |
| Illinois | 27 | $9.62 | $38.29 | $279.81 |
| Iowa | 18 | $9.56 | $9.76 | $48.76 |
| Kansas | 5 | not published by hospital | not published by hospital | not published by hospital |
| Kentucky | 10 | $3.60 | $114.82 | $157.78 |
| Louisiana | 6 | not published by hospital | not published by hospital | not published by hospital |
| Maine | 3 | $71.68 | $71.68 | $71.68 |
| Maryland | 1 | not published by hospital | not published by hospital | not published by hospital |
| Michigan | 17 | $7.41 | $7.41 | $7.41 |
| Minnesota | 8 | not published by hospital | not published by hospital | not published by hospital |
| Missouri | 14 | not published by hospital | not published by hospital | not published by hospital |
| Montana | 1 | not published by hospital | not published by hospital | not published by hospital |
| Nebraska | 7 | $41.79 | $41.79 | $84.58 |
| New Jersey | 21 | $4.94 | $5.19 | $5.19 |
| New Mexico | 2 | not published by hospital | not published by hospital | not published by hospital |
| New York | 19 | $4.94 | $4.94 | $36.00 |
| North Carolina | 13 | $22.78 | $22.78 | $22.78 |
| North Dakota | 2 | not published by hospital | not published by hospital | not published by hospital |
| Ohio | 29 | $10.15 | $10.15 | $10.15 |
| Oklahoma | 8 | $13.14 | $13.14 | $13.14 |
| Oregon | 4 | $6.51 | $6.51 | $6.51 |
| Pennsylvania | 21 | $29.80 | $51.00 | $378.00 |
| South Carolina | 8 | not published by hospital | not published by hospital | not published by hospital |
| South Dakota | 5 | not published by hospital | not published by hospital | not published by hospital |
| Tennessee | 9 | not published by hospital | not published by hospital | not published by hospital |
| Texas | 82 | $5.52 | $18.72 | $26.25 |
| Virginia | 21 | not published by hospital | not published by hospital | not published by hospital |
| Washington | 12 | $7.36 | $7.45 | $10.46 |
| West Virginia | 1 | $3.60 | $3.60 | $3.60 |
| Wisconsin | 23 | $6.53 | $9.62 | $17.07 |
All hospitals
| Hospital | Location | Cash price | Negotiated range |
|---|---|---|---|
| Claiborne Medical Center | Tazewell, TN | not published | $2.43 – $5.85 |
| CHRISTUS Spohn Hospital - Kleberg | Kingsville, TX | not published | $5.15 – $15.89 |
| CHRISTUS Spohn Hospital - Beeville | Beeville, TX | not published | $5.15 – $15.89 |
| CHRISTUS Spohn Hospital - Alice | Alice, TX | not published | $5.15 – $15.89 |
| CHRISTUS Southeast Texas Jasper Memorial | Jasper, TX | not published | $5.13 – $20.51 |
| CHRISTUS Trinity Mother Frances Hospital - Winnsboro | Winnsboro, TX | not published | $5.16 – $7.95 |
| CHRISTUS Trinity Mother Frances Hospital - South Tyler | Tyler, TX | not published | $4.81 – $9.62 |
| CHRISTUS Trinity Mother Frances Hospital - Sulphur Springs | Sulphur Springs, TX | not published | $5.24 – $10.48 |
| CHRISTUS Trinity Mother Frances Hospital - Jacksonville | Jacksonville, TX | not published | $5.16 – $7.95 |
| CHRISTUS Trinity Mother Frances Louis & Peaches Owens Heart Hospital | Tyler, TX | not published | $4.81 – $9.62 |
| CHRISTUS Good Shepherd Medical Center - Marshall | Marshall, TX | not published | $4.62 – $9.72 |
| AdventHealth Polk | Columbus, NC | not published | $5.34 – $5.34 |
| AdventHealth Castle Rock | Castle Rock, CO | not published | $0.92 – $10.10 |
| Providence St Mary Medical Center | Walla Walla, WA | not published | $4.83 – $29.89 |
| Providence Milwaukie Hospital | Milwaukie, OR | not published | $5.06 – $10.28 |
| Covenant Hospital Levelland | Levelland, TX | not published | $4.99 – $5.42 |
| Providence Saint John's Health Center | Santa Monica, CA | not published | $0.52 – $11.09 |
| SSM Health Ripon Community Hospital | Ripon, WI | not published | $5.51 – $13.86 |
| SSM Health Monroe Hospital | Monroe, WI | not published | $5.13 – $14.04 |
| Monmouth Medical Center Southern Campus | Lakewood, NJ | not published | $4.59 – $11.06 |
| Providence St Joseph Hospital Orange | Orange, CA | not published | $4.06 – $11.09 |
| Doctors Hospital | Columbus, OH | not published | $5.46 – $13.79 |
| SSM Health St. Anthony Hospital - Shawnee | Shawnee, OK | not published | $5.13 – $10.01 |
| University Hospitals Ahuja Medical Center | Beachwood, OH | not published | $5.14 – $9.25 |
| St Patrick Hospital - Broadway Campus | Missoula, MT | not published | $5.19 – $16.01 |
| Santa Rosa Memorial Hospital | Santa Rosa, CA | not published | $3.34 – $11.09 |
| Monmouth Medical Center | Long Branch, NJ | not published | $4.59 – $11.20 |
| Jersey City Medical Center | Jersey City, NJ | not published | $0.01 – $11.92 |
| SSM Health St. Joseph Hospital - Lake Saint Louis | Lake Saint Louis, MO | not published | $0.61 – $8.55 |
| AdventHealth Porter | Denver, CO | not published | $0.92 – $10.10 |
| Adventhealth Redmond | Rome, GA | not published | $4.78 – $15.17 |
| Adventhealth Central Texas | Killeen, TX | not published | $5.46 – $17.90 |
| AdventHealth Avista | Louisville, CO | not published | $0.92 – $10.10 |
| St Jude Medical Center | Fullerton, CA | not published | $4.16 – $11.09 |
| Providence Saint Joseph Medical Center | Burbank, CA | not published | $5.14 – $11.09 |
| UnityPoint Health - Trinity Muscatine | Muscatine, IA | not published | $4.83 – $16.07 |
| Sanford Sheldon Medical Center | Sheldon, IA | not published | $5.03 – $5.03 |
| Sanford Aberdeen Medical Center | Aberdeen, SD | not published | $5.03 – $5.73 |
| Sanford Vermillion Hospital | Vermillion, SD | not published | $5.03 – $5.03 |
| Sanford Canton Inwood Medical Center | Canton, SD | not published | $5.03 – $5.03 |
| Sanford Medical Center Mayville | Mayville, ND | not published | $5.03 – $5.03 |
| Sanford Chamberlain Medical Center | Chamberlain, SD | not published | $5.03 – $5.03 |
| Sanford Medical Center Hillsboro | Hillsboro, ND | not published | $5.03 – $5.03 |
| Sanford Tracy Hospital | Tracy, MN | not published | $5.03 – $5.03 |
| Sanford Worthington Medical Center | Worthington, MN | not published | $4.81 – $5.73 |
| Sanford Bemidji Medical Center | Bemidji, MN | not published | $4.90 – $5.73 |
| Redwood Memorial Hospital | Fortuna, CA | not published | $4.02 – $10.37 |
| Healdsburg Hospital | Healdsburg, CA | not published | $5.14 – $10.18 |
| SSM Health St. Mary's Hospital - St. Louis | Richmond Heights, MO | not published | $0.61 – $8.55 |
| Newark Beth Israel Medical Center | Newark, NJ | not published | $4.59 – $11.36 |
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