Alpha-1-proteinase inhibitor (human) 1,000 mg (+/-) IV solution cost at US hospitals
ALPHA-1-PROTEINASE INHIBITOR (HUMAN) 1,000 MG (+/-) IV SOLUTION · HCPCS J0256
$3.25
lowest cash price
$13.14
national median
$378.00
highest cash price
218
hospitals with a published cash price
Middle half of hospitals (25th–75th percentile) against the full range. The same procedure varies $3.25–$378.00 — the variation is the story.
Median cash price over time
Sep 1, 2025 ($71.68) → Sep 1, 2026 ($4.94)
By state
| State | Hospitals | Lowest cash | Median | Highest |
|---|---|---|---|---|
| Alaska | 1 | not published by hospital | not published by hospital | not published by hospital |
| Arizona | 1 | $7.26 | $7.26 | $7.26 |
| California | 52 | $3.98 | $4.28 | $19.69 |
| Colorado | 11 | $53.00 | $53.00 | $135.53 |
| Florida | 53 | $3.25 | $3.25 | $49.75 |
| Georgia | 19 | $13.53 | $13.53 | $13.53 |
| Hawaii | 1 | $5.74 | $5.74 | $5.74 |
| Illinois | 27 | $9.62 | $38.29 | $279.81 |
| Iowa | 18 | $9.56 | $9.76 | $48.76 |
| Kansas | 5 | not published by hospital | not published by hospital | not published by hospital |
| Kentucky | 10 | $3.60 | $114.82 | $157.78 |
| Louisiana | 6 | not published by hospital | not published by hospital | not published by hospital |
| Maine | 3 | $71.68 | $71.68 | $71.68 |
| Maryland | 1 | not published by hospital | not published by hospital | not published by hospital |
| Michigan | 17 | $7.41 | $7.41 | $7.41 |
| Minnesota | 8 | not published by hospital | not published by hospital | not published by hospital |
| Missouri | 14 | not published by hospital | not published by hospital | not published by hospital |
| Montana | 1 | not published by hospital | not published by hospital | not published by hospital |
| Nebraska | 7 | $41.79 | $41.79 | $84.58 |
| New Jersey | 21 | $4.94 | $5.19 | $5.19 |
| New Mexico | 2 | not published by hospital | not published by hospital | not published by hospital |
| New York | 19 | $4.94 | $4.94 | $36.00 |
| North Carolina | 13 | $22.78 | $22.78 | $22.78 |
| North Dakota | 2 | not published by hospital | not published by hospital | not published by hospital |
| Ohio | 29 | $10.15 | $10.15 | $10.15 |
| Oklahoma | 8 | $13.14 | $13.14 | $13.14 |
| Oregon | 4 | $6.51 | $6.51 | $6.51 |
| Pennsylvania | 21 | $29.80 | $51.00 | $378.00 |
| South Carolina | 8 | not published by hospital | not published by hospital | not published by hospital |
| South Dakota | 5 | not published by hospital | not published by hospital | not published by hospital |
| Tennessee | 9 | not published by hospital | not published by hospital | not published by hospital |
| Texas | 82 | $5.52 | $18.72 | $26.25 |
| Virginia | 21 | not published by hospital | not published by hospital | not published by hospital |
| Washington | 12 | $7.36 | $7.45 | $10.46 |
| West Virginia | 1 | $3.60 | $3.60 | $3.60 |
| Wisconsin | 23 | $6.53 | $9.62 | $17.07 |
All hospitals
| Hospital | Location | Cash price | Negotiated range |
|---|---|---|---|
| Kettering Health Hamilton (Fort Hamilton) | Hamilton, OH | not published | $5.46 – $14.40 |
| Kettering Health Greene Memorial | Xenia, OH | not published | $5.46 – $14.40 |
| Soin Medical Center | Beaver Creek, OH | not published | $5.46 – $14.40 |
| Kettering Health Dayton (Grandview) | Dayton, OH | not published | $5.46 – $14.40 |
| Kettering Health Miamisburg (Sycamore) | Miamisburg, OH | not published | $5.46 – $14.40 |
| Kettering Health Main Campus (Kettering) | Kettering, OH | not published | $5.46 – $14.40 |
| MUSC Health Lancaster Medical Center | Lancaster, SC | not published | $5.36 – $7.41 |
| MUSC Health Kershaw Medical Center | Camden, SC | not published | $3.87 – $7.41 |
| MUSC Health Florence Medical Center | Florence, SC | not published | $4.83 – $7.41 |
| MUSC Health Chester Medical Center | Chester, SC | not published | $5.36 – $8.10 |
| MUSC Health Main Campus - Charleston | Charleston, SC | not published | $3.84 – $10.56 |
| MUSC Health Black River Medical Center | Cades, SC | not published | $4.68 – $7.41 |
| Virginia Mason Medical Center | Seattle, WA | not published | $3.82 – $15.91 |
| Clifton Springs Hospital and Clinic | Clifton Springs, NY | not published | $5.05 – $6.20 |
| Newark Wayne Community Hospital | Newark, NY | not published | $5.29 – $7.13 |
| The Unity Hospital of Rochester | Rochester, NY | not published | $5.29 – $6.20 |
| Rochester General Hospital | Rochester, NY | not published | $5.29 – $9.48 |
| MultiCare Valley Hospital | Spokane Valley, WA | not published | $5.19 – $1,137.14 |
| MultiCare Mary Bridge Children's Hospital | Tacoma, WA | not published | $4.78 – $4,164.41 |
| MultiCare Good Samaritan Hospital | Puyallup, WA | not published | $5.04 – $1,272.76 |
| MultiCare Capital Medical Center | Olympia, WA | not published | $4.35 – $1,836.40 |
| MEDICAL CITY GREEN OAKS HOSPITAL | DALLAS, TX | not published | $5.14 – $5.14 |
| MultiCare Auburn Medical Center | Auburn, WA | not published | $4.65 – $1,244.00 |
| MEDICAL CITY FORT WORTH HOSPITAL | FT WORTH, TX | not published | $4.99 – $31.40 |
| Houston Methodist Cypress Hospital | Cypress, TX | not published | $5.46 – $10.64 |
| Houston Methodist Continuing Care Hospital | Katy, TX | not published | $11.66 – $30.52 |
| Houston Methodist The Woodlands Hospital | The Woodlands, TX | not published | $5.46 – $10.91 |
| Houston Methodist Clear Lake Hospital | Nassau Bay, TX | not published | $5.46 – $10.64 |
| Houston Methodist Willowbrook Hospital | Houston, TX | not published | $5.46 – $10.64 |
| Houston Methodist Baytown Hospital | Baytown, TX | not published | $5.46 – $10.64 |
| Houston Methodist West Hospital | Houston, TX | not published | $5.46 – $21.83 |
| Houston Methodist Sugar Land Hospital | Sugar Land, TX | not published | $5.46 – $10.64 |
| Houston Methodist Hospital | Houston, TX | not published | $5.46 – $21.83 |
| Texas Health Huguley Hospital Fort Worth South | Burleson, TX | not published | $5.13 – $10.27 |
| Texas Health Hospital Mansfield | Mansfield, TX | not published | $5.13 – $10.27 |
| OSF Healthcare Saint Katharine Medical Center | Dixon, IL | not published | $5.14 – $5.37 |
| OSF St Mary Medical Center | Galesburg, IL | not published | $5.14 – $8.05 |
| OSF St Joseph Medical Center | Bloomington, IL | not published | $5.14 – $14.12 |
| OSF Saint James John W Albrecht Medical Center | Pontiac, IL | not published | $5.14 – $5.24 |
| OSF Saint Francis Medical Center | Peoria, IL | not published | $4.61 – $17.48 |
| OSF Saint Elizabeth Medical Center | Ottawa, IL | not published | $5.14 – $5.24 |
| OSF Saint Anthony's Health Center | Alton, IL | not published | $5.14 – $5.24 |
| OSF Saint Anthony Medical Center | Rockford, IL | not published | $4.61 – $17.99 |
| MEDICAL CITY ARGYLE HOSPITAL | Argyle, TX | not published | $4.99 – $31.40 |
| CHRISTUS Health - West Beaumont | Beaumont, TX | not published | $5.10 – $18.14 |
| CHRISTUS Good Shepherd Medical Center - Longview | Longview, TX | not published | $4.62 – $9.72 |
| Gerald Champion Regional Medical Center | Alamogordo, NM | not published | $4.33 – $7.77 |
| CHRISTUS Spohn Hospital Corpus Christi - Shoreline | Corpus Christi, TX | not published | $4.95 – $15.89 |
| CHRISTUS St. Michael Rehabilitation | Texarkana, TX | not published | $2.09 – $10.00 |
| CHRISTUS St. Michael Hospital - Atlanta | Atlanta, TX | not published | $2.09 – $10.00 |
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