Alpha-1-proteinase inhibitor (human) 1,000 mg (+/-) IV solution cost at US hospitals
ALPHA-1-PROTEINASE INHIBITOR (HUMAN) 1,000 MG (+/-) IV SOLUTION · HCPCS J0256
$3.25
lowest cash price
$13.14
national median
$378.00
highest cash price
218
hospitals with a published cash price
Middle half of hospitals (25th–75th percentile) against the full range. The same procedure varies $3.25–$378.00 — the variation is the story.
Median cash price over time
Sep 1, 2025 ($71.68) → Sep 1, 2026 ($4.94)
By state
| State | Hospitals | Lowest cash | Median | Highest |
|---|---|---|---|---|
| Alaska | 1 | not published by hospital | not published by hospital | not published by hospital |
| Arizona | 1 | $7.26 | $7.26 | $7.26 |
| California | 52 | $3.98 | $4.28 | $19.69 |
| Colorado | 11 | $53.00 | $53.00 | $135.53 |
| Florida | 53 | $3.25 | $3.25 | $49.75 |
| Georgia | 19 | $13.53 | $13.53 | $13.53 |
| Hawaii | 1 | $5.74 | $5.74 | $5.74 |
| Illinois | 27 | $9.62 | $38.29 | $279.81 |
| Iowa | 18 | $9.56 | $9.76 | $48.76 |
| Kansas | 5 | not published by hospital | not published by hospital | not published by hospital |
| Kentucky | 10 | $3.60 | $114.82 | $157.78 |
| Louisiana | 6 | not published by hospital | not published by hospital | not published by hospital |
| Maine | 3 | $71.68 | $71.68 | $71.68 |
| Maryland | 1 | not published by hospital | not published by hospital | not published by hospital |
| Michigan | 17 | $7.41 | $7.41 | $7.41 |
| Minnesota | 8 | not published by hospital | not published by hospital | not published by hospital |
| Missouri | 14 | not published by hospital | not published by hospital | not published by hospital |
| Montana | 1 | not published by hospital | not published by hospital | not published by hospital |
| Nebraska | 7 | $41.79 | $41.79 | $84.58 |
| New Jersey | 21 | $4.94 | $5.19 | $5.19 |
| New Mexico | 2 | not published by hospital | not published by hospital | not published by hospital |
| New York | 19 | $4.94 | $4.94 | $36.00 |
| North Carolina | 13 | $22.78 | $22.78 | $22.78 |
| North Dakota | 2 | not published by hospital | not published by hospital | not published by hospital |
| Ohio | 29 | $10.15 | $10.15 | $10.15 |
| Oklahoma | 8 | $13.14 | $13.14 | $13.14 |
| Oregon | 4 | $6.51 | $6.51 | $6.51 |
| Pennsylvania | 21 | $29.80 | $51.00 | $378.00 |
| South Carolina | 8 | not published by hospital | not published by hospital | not published by hospital |
| South Dakota | 5 | not published by hospital | not published by hospital | not published by hospital |
| Tennessee | 9 | not published by hospital | not published by hospital | not published by hospital |
| Texas | 82 | $5.52 | $18.72 | $26.25 |
| Virginia | 21 | not published by hospital | not published by hospital | not published by hospital |
| Washington | 12 | $7.36 | $7.45 | $10.46 |
| West Virginia | 1 | $3.60 | $3.60 | $3.60 |
| Wisconsin | 23 | $6.53 | $9.62 | $17.07 |
All hospitals
| Hospital | Location | Cash price | Negotiated range |
|---|---|---|---|
| SSM Health St. Mary's Hospital - Jefferson City | Jefferson City, MO | not published | $5.10 – $9.24 |
| Adventhealth South Overland Park | Overland Park, KS | not published | $5.09 – $15.83 |
| Robert Wood Johnson University Hospital Somerset | Somerville, NJ | not published | $0.01 – $11.06 |
| Robert Wood Johnson University Hospital Hamilton | Hamilton Township, NJ | not published | $4.59 – $11.06 |
| University Hospitals Regional Hospitals - Geauga Medical Center | Chardon, OH | not published | $5.14 – $9.25 |
| Grady Memorial Hospital | Delaware, OH | not published | $5.46 – $33.09 |
| SSM Health Waupun Memorial Hospital | Waupun, WI | not published | $5.51 – $13.86 |
| Robert Wood Johnson University Hospital | New Brunswick, NJ | not published | $4.59 – $12.41 |
| Riverside Methodist Hospital | Columbus, OH | not published | $5.46 – $13.79 |
| SSM Health St. Agnes Hospital - Fond du Lac | Fond Du Lac, WI | not published | $3.85 – $13.86 |
| University Hospitals Cleveland Medical Center | Cleveland OH 44106|3999 Richmond Road, OH | not published | $5.14 – $9.25 |
| University Hospitals Portage Medical Center | Ravenna OH 44266, OH | not published | $5.14 – $9.25 |
| University Hospitals Parma Medical Center | Parma OH 44129|7007 Powers Boulevard, OH | not published | $5.14 – $9.25 |
| University Hospitals Lake West Medical Center | Willoughby OH 44094|7590 Auburn Road, OH | not published | $5.14 – $9.25 |
| University Hospitals Samaritan Medical Center | Ashland, OH | not published | $12.61 – $12.61 |
| University Hospitals St. John Medical Center | Westlake OH, OH | not published | $8.70 – $19.88 |
| University Hospitals Geneva Medical Center | Geneva, OH | not published | $16.73 – $19.88 |
| University Hospitals Elyria Medical Center | Elyria, OH | not published | $5.14 – $9.25 |
| Corewell Health Pennock | Hastings, MI | not published | $5.38 – $5.38 |
| Advocate Trinity Hospital | Chicago, IL | not published | $7.52 – $16.33 |
| Spring Harbor Hospital | Westbrook, ME | not published | $4.83 – $9.43 |
| University Hospitals Conneaut Medical Center | Conneaut, OH | not published | $5.68 – $18.08 |
| Advocate South Suburban Hospital | Hazel Crest, IL | not published | $7.52 – $16.33 |
| Advocate Sherman Hospital | Elgin, IL | not published | $4.03 – $11.35 |
| Advocate Illinois Masonic Medical Center | Chicago, IL | not published | $7.52 – $16.33 |
| University Hospitals Beachwood Medical Center | Beachwood, OH | not published | $5.14 – $9.25 |
| Cooperman Barnabas Medical Center | Livingston, NJ | not published | $4.59 – $11.42 |
| SSM Health St. Joseph Hospital- Wentzville | Wentzville, MO | not published | $0.61 – $8.55 |
| Petaluma Valley Hospital | Petaluma, CA | not published | $3.11 – $11.09 |
| SSM Health Saint Louis University Hospital | Saint Louis, MO | not published | $1.12 – $10.12 |
| SSM Health DePaul Hospital - St. Louis | Bridgeton, MO | not published | $0.61 – $8.55 |
| Adventhealth Shawnee Mission | Shawnee Mission, KS | not published | $5.09 – $15.83 |
| SSM Health St. Clare Hospital - Fenton | Fenton, MO | not published | $0.61 – $8.55 |
| O'Bleness Hospital | Athens, OH | not published | $5.46 – $33.09 |
| Mansfield Hospital | Mansfield, OH | not published | $5.46 – $33.09 |
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