Alteplase 100 mg infusion from pyxis vial cost at US hospitals
ALTEPLASE 100 MG INFUSION FROM PYXIS VIAL · HCPCS J2997
$556.56
lowest cash price
$15,857.45
national median
$102,964.26
highest cash price
530
hospitals with a published cash price
Middle half of hospitals (25th–75th percentile) against the full range. The same procedure varies $556.56–$102,964.26 — the variation is the story.
Median cash price over time
Sep 1, 2025 ($21,013.50) → Sep 1, 2026 ($21,257.00)
By state
| State | Hospitals | Lowest cash | Median | Highest |
|---|---|---|---|---|
| Alaska | 5 | $960.10 | $19,668.33 | $45,243.16 |
| Arizona | 4 | $8,025.26 | $8,742.97 | $30,343.35 |
| Arkansas | 8 | $8,219.50 | $17,732.73 | $37,806.50 |
| California | 77 | $570.46 | $13,614.60 | $31,630.68 |
| Colorado | 13 | $2,478.25 | $2,478.25 | $2,478.25 |
| Florida | 70 | $556.56 | $1,488.87 | $20,592.84 |
| Georgia | 15 | $2,312.61 | $2,336.68 | $43,507.20 |
| Hawaii | 1 | $19,012.53 | $19,012.53 | $19,012.53 |
| Illinois | 24 | $979.91 | $25,018.70 | $56,853.12 |
| Indiana | 19 | $1,611.20 | $21,257.00 | $87,556.86 |
| Iowa | 20 | $12,850.08 | $25,477.05 | $25,477.05 |
| Kansas | 5 | $1,863.51 | $1,863.51 | $1,863.51 |
| Kentucky | 25 | $748.42 | $32,310.00 | $87,556.86 |
| Louisiana | 4 | $2,559.30 | $2,559.30 | $2,559.30 |
| Maine | 7 | $834.51 | $14,052.42 | $26,765.42 |
| Maryland | 2 | $9,848.40 | $9,848.40 | $9,848.40 |
| Michigan | 15 | $630.01 | $630.01 | $4,598.72 |
| Minnesota | 15 | $4,197.25 | $12,473.57 | $13,925.31 |
| Mississippi | 1 | $10,982.86 | $10,982.86 | $10,982.86 |
| Missouri | 20 | $17,160.70 | $17,217.91 | $21,450.88 |
| Montana | 2 | $21,626.26 | $21,626.26 | $21,626.26 |
| Nebraska | 12 | $3,906.49 | $17,833.94 | $36,092.49 |
| Nevada | 3 | $1,797.84 | $2,600.22 | $3,627.63 |
| New Hampshire | 1 | $31,580.10 | $31,580.10 | $31,580.10 |
| New Jersey | 12 | not published by hospital | not published by hospital | not published by hospital |
| New Mexico | 2 | $1,358.41 | $1,358.41 | $2,819.32 |
| New York | 3 | $28,799.19 | $28,799.19 | $28,799.19 |
| North Carolina | 13 | $705.99 | $17,085.20 | $17,085.20 |
| North Dakota | 3 | $7,445.27 | $9,173.77 | $13,143.43 |
| Ohio | 64 | $8,580.35 | $31,563.16 | $102,964.26 |
| Oklahoma | 13 | $5,084.26 | $5,084.26 | $36,081.48 |
| Oregon | 12 | $806.03 | $23,342.81 | $26,431.24 |
| Pennsylvania | 19 | $612.00 | $5,517.60 | $40,758.00 |
| South Carolina | 11 | $73,130.99 | $73,130.99 | $81,843.35 |
| South Dakota | 5 | $12,473.57 | $12,473.57 | $23,176.60 |
| Tennessee | 26 | $4,048.17 | $8,997.49 | $11,037.54 |
| Texas | 113 | $604.61 | $15,857.45 | $45,243.16 |
| Virginia | 37 | $4,871.66 | $56,498.32 | $92,403.78 |
| Washington | 23 | $635.31 | $12,548.99 | $24,345.24 |
| West Virginia | 8 | $729.05 | $12,124.70 | $32,310.00 |
| Wisconsin | 8 | not published by hospital | not published by hospital | not published by hospital |
All hospitals
| Hospital | Location | Cash price | Negotiated range |
|---|---|---|---|
| Emory Hospital Perry | Perry, GA | $43,507.20 | not published |
| Emory Hospital Warner Robins | Warner Robins, GA | $43,507.20 | $95.09 – $201.59 |
| St Joseph Warren Hospital | Warren, OH | $44,881.86 | not published |
| Covenant Medical Center | Lubbock, TX | $45,243.16 | $95.09 – $329.53 |
| St Elias Specialty Hospital | Anchorage, AK | $45,243.16 | $92.24 – $329.53 |
| Covenant Hospital Levelland | Levelland, TX | $45,243.16 | $92.24 – $100.32 |
| St Elizabeth Boardman Hospital | Youngstown, OH | $47,521.98 | not published |
| St Elizabeth Youngstown Hospital | Youngstown, OH | $49,634.04 | not published |
| Northwestern Lake Forest Hospital DBA Northwestern Medicine Catherine Gratz Griffin Lake Forest Hospital | Lake Forest, IL | $52,993.50 | not published |
| Maryview Hospital | Portsmouth, VA | $56,498.32 | not published |
| Harbour View Medical Center | Suffolk, VA | $56,498.32 | not published |
| Northwestern Medicine Central DuPage Hospital | IL 60190, IL | $56,853.12 | not published |
| Northwestern Memorial Hospital | Chicago, IL | $56,853.12 | not published |
| Southampton Medical Center | Franklin, VA | $58,082.38 | not published |
| Richmond Community Hospital | Richmond, VA | $60,722.48 | not published |
| Mary Immaculate Hospital | Newport News, VA | $63,098.59 | not published |
| St Francis Downtown | Greenville, SC | $73,130.99 | not published |
| St Mary's Hospital | Richmond, VA | $78,675.22 | not published |
| St Francis Eastside | Greenville, SC | $81,843.35 | not published |
| Memorial Regional Hospital | Mechanicsville, VA | $83,163.40 | not published |
| Southside Regional Medical Center | Petersburg, VA | $86,595.55 | not published |
| Baptist Health Floyd | New Albany, IN | $87,556.86 | $90.21 – $1,744.74 |
| Baptist Health Hardin | Elizabethtown, KY | $87,556.86 | $111.03 – $2,326.32 |
| Baptist Health Corbin | Corbin, KY | $87,556.86 | $112.14 – $2,326.32 |
| Baptist Health La Grange | La Grange, KY | $87,556.86 | $112.14 – $2,326.32 |
| Baptist Health Lexington | Lexington, KY | $87,556.86 | $105.14 – $2,364.70 |
| Baptist Health Louisville | Louisville, KY | $87,556.86 | $100.92 – $2,326.32 |
| Baptist Health Paducah | Paducah, KY | $87,556.86 | $95.09 – $2,326.32 |
| St Francis Medical Center | Midlothian, VA | $92,403.78 | not published |
| St Ritas Medical Center | Lima, OH | $102,964.26 | not published |
| RESEARCH PSYCHIATRIC CENTER | Kansas City, MO | not published | $95.09 – $97.58 |
| RESEARCH MEDICAL CENTER | Kansas City, MO | not published | $93.83 – $97.58 |
| MENORAH MEDICAL CENTER | Overland Park, KS | not published | $93.83 – $97.58 |
| LEE'S SUMMIT MEDICAL CENTER | Lee's Summit, MO | not published | $93.83 – $97.58 |
| CENTERPOINT MEDICAL CENTER | Independence, MO | not published | $93.83 – $97.58 |
| LAFAYETTE REGIONAL HEALTH CENTER | Lexington, MO | not published | $93.83 – $97.58 |
| HCA FLORIDA WESTSIDE HOSPITAL | PLANTATION, FL | not published | $92.24 – $156.90 |
| HCA FLORIDA OCALA HOSPITAL | SUMMERFIELD, FL | not published | $92.24 – $285.27 |
| HCA FLORIDA SOUTH TAMPA HOSPITAL | Tampa, FL | not published | $92.24 – $204.44 |
| HCA FLORIDA UNIVERSITY HOSPITAL | Davie, FL | not published | $156.90 – $156.90 |
| UCF LAKE NONA HOSPITAL | Orlando, FL | not published | $92.24 – $285.27 |
| HCA FLORIDA TWIN CITIES HOSPITAL | DEFUNIAK SPRINGS, FL | not published | $92.24 – $285.27 |
| HCA FLORIDA TRINITY HOSPITAL | TRINITY, FL | not published | $92.24 – $204.44 |
| HCA FLORIDA ST. PETERSBURG HOSPITAL | NORTH, FL | not published | $92.24 – $204.44 |
| HCA FLORIDA ST. LUCIE HOSPITAL | STUART, FL | not published | $92.24 – $156.90 |
| HCA FLORIDA SARASOTA DOCTORS HOSPITAL | VENICE, FL | not published | $92.24 – $204.44 |
| HCA FLORIDA PUTNAM HOSPITAL | Palatka, FL | not published | $92.24 – $285.27 |
| HCA FLORIDA POINCIANA HOSPITAL | DAVENPORT, FL | not published | $92.24 – $285.27 |
| HCA FLORIDA PALMS WEST HOSPITAL | LOXAHATCHEE, FL | not published | $92.24 – $156.90 |
| OVIEDO MEDICAL CENTER | Oviedo, FL | not published | $92.24 – $285.27 |
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