Alteplase 100 mg infusion from pyxis vial cost at US hospitals
ALTEPLASE 100 MG INFUSION FROM PYXIS VIAL · HCPCS J2997
$556.56
lowest cash price
$15,857.45
national median
$102,964.26
highest cash price
530
hospitals with a published cash price
Middle half of hospitals (25th–75th percentile) against the full range. The same procedure varies $556.56–$102,964.26 — the variation is the story.
Median cash price over time
Sep 1, 2025 ($21,013.50) → Sep 1, 2026 ($21,257.00)
By state
| State | Hospitals | Lowest cash | Median | Highest |
|---|---|---|---|---|
| Alaska | 5 | $960.10 | $19,668.33 | $45,243.16 |
| Arizona | 4 | $8,025.26 | $8,742.97 | $30,343.35 |
| Arkansas | 8 | $8,219.50 | $17,732.73 | $37,806.50 |
| California | 77 | $570.46 | $13,614.60 | $31,630.68 |
| Colorado | 13 | $2,478.25 | $2,478.25 | $2,478.25 |
| Florida | 70 | $556.56 | $1,488.87 | $20,592.84 |
| Georgia | 15 | $2,312.61 | $2,336.68 | $43,507.20 |
| Hawaii | 1 | $19,012.53 | $19,012.53 | $19,012.53 |
| Illinois | 24 | $979.91 | $25,018.70 | $56,853.12 |
| Indiana | 19 | $1,611.20 | $21,257.00 | $87,556.86 |
| Iowa | 20 | $12,850.08 | $25,477.05 | $25,477.05 |
| Kansas | 5 | $1,863.51 | $1,863.51 | $1,863.51 |
| Kentucky | 25 | $748.42 | $32,310.00 | $87,556.86 |
| Louisiana | 4 | $2,559.30 | $2,559.30 | $2,559.30 |
| Maine | 7 | $834.51 | $14,052.42 | $26,765.42 |
| Maryland | 2 | $9,848.40 | $9,848.40 | $9,848.40 |
| Michigan | 15 | $630.01 | $630.01 | $4,598.72 |
| Minnesota | 15 | $4,197.25 | $12,473.57 | $13,925.31 |
| Mississippi | 1 | $10,982.86 | $10,982.86 | $10,982.86 |
| Missouri | 20 | $17,160.70 | $17,217.91 | $21,450.88 |
| Montana | 2 | $21,626.26 | $21,626.26 | $21,626.26 |
| Nebraska | 12 | $3,906.49 | $17,833.94 | $36,092.49 |
| Nevada | 3 | $1,797.84 | $2,600.22 | $3,627.63 |
| New Hampshire | 1 | $31,580.10 | $31,580.10 | $31,580.10 |
| New Jersey | 12 | not published by hospital | not published by hospital | not published by hospital |
| New Mexico | 2 | $1,358.41 | $1,358.41 | $2,819.32 |
| New York | 3 | $28,799.19 | $28,799.19 | $28,799.19 |
| North Carolina | 13 | $705.99 | $17,085.20 | $17,085.20 |
| North Dakota | 3 | $7,445.27 | $9,173.77 | $13,143.43 |
| Ohio | 64 | $8,580.35 | $31,563.16 | $102,964.26 |
| Oklahoma | 13 | $5,084.26 | $5,084.26 | $36,081.48 |
| Oregon | 12 | $806.03 | $23,342.81 | $26,431.24 |
| Pennsylvania | 19 | $612.00 | $5,517.60 | $40,758.00 |
| South Carolina | 11 | $73,130.99 | $73,130.99 | $81,843.35 |
| South Dakota | 5 | $12,473.57 | $12,473.57 | $23,176.60 |
| Tennessee | 26 | $4,048.17 | $8,997.49 | $11,037.54 |
| Texas | 113 | $604.61 | $15,857.45 | $45,243.16 |
| Virginia | 37 | $4,871.66 | $56,498.32 | $92,403.78 |
| Washington | 23 | $635.31 | $12,548.99 | $24,345.24 |
| West Virginia | 8 | $729.05 | $12,124.70 | $32,310.00 |
| Wisconsin | 8 | not published by hospital | not published by hospital | not published by hospital |
All hospitals
| Hospital | Location | Cash price | Negotiated range |
|---|---|---|---|
| University Hospitals Regional Hospitals - Geauga Medical Center | Chardon, OH | $31,563.16 | $95.09 – $171.16 |
| University Hospitals Lake West Medical Center | Willoughby OH 44094|7590 Auburn Road, OH | $31,563.16 | $54.20 – $171.16 |
| University Hospitals Samaritan Medical Center | Ashland, OH | $31,563.16 | $95.09 – $229.16 |
| University Hospitals Geneva Medical Center | Geneva, OH | $31,563.16 | $304.01 – $304.01 |
| University Hospitals Portage Medical Center | Ravenna OH 44266, OH | $31,563.16 | $95.09 – $171.16 |
| University Hospitals St. John Medical Center | Westlake OH, OH | $31,563.16 | $95.09 – $171.16 |
| University Hospitals Ahuja Medical Center | Beachwood, OH | $31,563.16 | $95.09 – $613.47 |
| MaineHealth - Memorial Hospital | North Conway, NH | $31,580.10 | $88.97 – $732.82 |
| Providence Cedars-Sinai Tarzana Medical Center | Tarzana, CA | $31,630.68 | $92.10 – $196.64 |
| Providence Holy Cross Medical Center | Mission Hills, CA | $31,630.68 | $92.10 – $196.64 |
| Providence Little Co of Mary Med Center San Pedro | San Pedro, CA | $31,630.68 | $92.10 – $196.64 |
| Providence Saint Joseph Medical Center | Burbank, CA | $31,630.68 | $92.10 – $196.64 |
| Providence Saint John's Health Center | Santa Monica, CA | $31,630.68 | $91.40 – $196.64 |
| Beckley ARH Hospital | Beckley, WV | $32,310.00 | $94.45 – $94.45 |
| Summers County ARH Hospital | Hinton, WV | $32,310.00 | $95.09 – $95.09 |
| Whitesburg ARH Hospital | Whitesburg, KY | $32,310.00 | $94.45 – $111.03 |
| Harlan ARH Hospital | KY 40831, KY | $32,310.00 | $94.45 – $111.03 |
| Middlesboro ARH Hospital | Middlesboro, KY | $32,310.00 | $94.45 – $111.03 |
| Mary Breckinridge ARH Hospital | Hayden, KY | $32,310.00 | $111.03 – $111.03 |
| ARH Our Lady of the Way Hospital | Martin, KY | $32,310.00 | $111.03 – $111.03 |
| Tug Valley ARH Regional Medical Center | Williamson, KY | $32,310.00 | $94.45 – $111.03 |
| Hazard ARH Regional Medical Center | Hazard, KY | $32,310.00 | $94.45 – $111.03 |
| Barbourville ARH Hospital | Barbourville, KY | $32,310.00 | $111.03 – $111.03 |
| Paintsville ARH Hospital | Paintsville, KY | $32,310.00 | $94.45 – $110.65 |
| Tiffin Hospital | Tiffin, OH | $33,001.38 | not published |
| Willard Hospital | Willard, OH | $33,001.38 | not published |
| Defiance Hospital | Defiance, OH | $34,849.44 | not published |
| Uchicago Medicine Adventhealth Hinsdale | Hinsdale, IL | $35,377.45 | $92.46 – $153.00 |
| CHI Health Plainview | Plainview, NE | $35,667.87 | $455.19 – $1,010.51 |
| Rappahannock General Hospital | Kilmarnock, VA | $35,905.47 | not published |
| Allen Hospital | Oberlin, OH | $35,905.50 | not published |
| Lorain Hospital | Lorain, OH | $35,905.50 | not published |
| Love County Health Center | Marietta, OK | $36,081.48 | $9,147.00 – $9,147.00 |
| CHI Health Schuyler | Schuyler, NE | $36,092.49 | $159.84 – $844.85 |
| Jewish Hospital | Cincinnati, OH | $36,961.56 | not published |
| Northwestern Medicine Palos Hospital | Palos Heights, IL | $37,462.07 | not published |
| CHI St. Vincent Hospital Hot Springs | Hot Springs, AR | $37,806.50 | $80.88 – $518.60 |
| Urbana Hospital | Urbana, OH | $38,281.62 | not published |
| UPMC Passavant-McCandless | Pittsburgh, PA | $39,117.00 | $49.03 – $186.38 |
| Anderson Hospital | Cincinnati, OH | $39,707.28 | not published |
| Clermont Hospital | Batavia, OH | $39,707.28 | not published |
| Kings Mills Hospital | Mason, OH | $39,707.28 | not published |
| Fairfield Hospital | Fairfield, OH | $39,707.28 | not published |
| Mercy West Hospital | Cincinnati, OH | $39,707.28 | not published |
| Marcum Wallace Hospital | Irvine, KY | $39,707.28 | not published |
| UPMC Muncy | Muncy, PA | $40,758.00 | $94.45 – $103.89 |
| UPMC Wellsboro | Wellsboro, PA | $40,758.00 | $94.45 – $177.50 |
| Springfield Medical Center | Springfield, OH | $41,713.74 | not published |
| Northwestern Medicine McHenry Hospital | McHenry, IL | $42,914.02 | not published |
| Lourdes Hospital | Paducah, KY | $43,297.80 | not published |
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