Alpha-1-proteinase inhibitor (human) 1,000 mg (+/-) IV solution cost at US hospitals
ALPHA-1-PROTEINASE INHIBITOR (HUMAN) 1,000 MG (+/-) IV SOLUTION · HCPCS J0256
$3.25
lowest cash price
$13.14
national median
$378.00
highest cash price
218
hospitals with a published cash price
Middle half of hospitals (25th–75th percentile) against the full range. The same procedure varies $3.25–$378.00 — the variation is the story.
Median cash price over time
Sep 1, 2025 ($71.68) → Sep 1, 2026 ($4.94)
By state
| State | Hospitals | Lowest cash | Median | Highest |
|---|---|---|---|---|
| Alaska | 1 | not published by hospital | not published by hospital | not published by hospital |
| Arizona | 1 | $7.26 | $7.26 | $7.26 |
| California | 52 | $3.98 | $4.28 | $19.69 |
| Colorado | 11 | $53.00 | $53.00 | $135.53 |
| Florida | 53 | $3.25 | $3.25 | $49.75 |
| Georgia | 19 | $13.53 | $13.53 | $13.53 |
| Hawaii | 1 | $5.74 | $5.74 | $5.74 |
| Illinois | 27 | $9.62 | $38.29 | $279.81 |
| Iowa | 18 | $9.56 | $9.76 | $48.76 |
| Kansas | 5 | not published by hospital | not published by hospital | not published by hospital |
| Kentucky | 10 | $3.60 | $114.82 | $157.78 |
| Louisiana | 6 | not published by hospital | not published by hospital | not published by hospital |
| Maine | 3 | $71.68 | $71.68 | $71.68 |
| Maryland | 1 | not published by hospital | not published by hospital | not published by hospital |
| Michigan | 17 | $7.41 | $7.41 | $7.41 |
| Minnesota | 8 | not published by hospital | not published by hospital | not published by hospital |
| Missouri | 14 | not published by hospital | not published by hospital | not published by hospital |
| Montana | 1 | not published by hospital | not published by hospital | not published by hospital |
| Nebraska | 7 | $41.79 | $41.79 | $84.58 |
| New Jersey | 21 | $4.94 | $5.19 | $5.19 |
| New Mexico | 2 | not published by hospital | not published by hospital | not published by hospital |
| New York | 19 | $4.94 | $4.94 | $36.00 |
| North Carolina | 13 | $22.78 | $22.78 | $22.78 |
| North Dakota | 2 | not published by hospital | not published by hospital | not published by hospital |
| Ohio | 29 | $10.15 | $10.15 | $10.15 |
| Oklahoma | 8 | $13.14 | $13.14 | $13.14 |
| Oregon | 4 | $6.51 | $6.51 | $6.51 |
| Pennsylvania | 21 | $29.80 | $51.00 | $378.00 |
| South Carolina | 8 | not published by hospital | not published by hospital | not published by hospital |
| South Dakota | 5 | not published by hospital | not published by hospital | not published by hospital |
| Tennessee | 9 | not published by hospital | not published by hospital | not published by hospital |
| Texas | 82 | $5.52 | $18.72 | $26.25 |
| Virginia | 21 | not published by hospital | not published by hospital | not published by hospital |
| Washington | 12 | $7.36 | $7.45 | $10.46 |
| West Virginia | 1 | $3.60 | $3.60 | $3.60 |
| Wisconsin | 23 | $6.53 | $9.62 | $17.07 |
All hospitals
| Hospital | Location | Cash price | Negotiated range |
|---|---|---|---|
| CHI Health Schuyler | Schuyler, NE | $84.58 | $21.32 – $112.66 |
| CHI Saint Joseph Health - Saint Joseph London | London, KY | $111.79 | $6.00 – $285.09 |
| CHI Saint Joseph Health - Saint Joseph Mount Sterling | Mt. Sterling, KY | $114.82 | $6.00 – $285.09 |
| CHI Saint Joseph Health - Saint Joseph East | Lexington, KY | $125.84 | $6.00 – $285.09 |
| CHI Saint Joseph Health - Flaget Memorial Hospital | Bardstown, KY | $132.92 | $6.00 – $285.09 |
| HCA HealthONE AURORA | Aurora, CO | $135.53 | $5.84 – $15.42 |
| CHI Saint Joseph Health - Saint Joseph Berea | Berea, KY | $151.02 | $15.27 – $285.09 |
| CHI Saint Joseph Health - Saint Joseph Hospital | Lexington, KY | $157.78 | $6.00 – $285.09 |
| Uchicago Medicine Adventhealth Bolingbrook | Bolingbrook, IL | $279.81 | $5.46 – $8.84 |
| Uchicago Medicine Adventhealth La Grange | La Grange, IL | $279.81 | $5.34 – $8.84 |
| Uchicago Medicine Adventhealth Hinsdale | Hinsdale, IL | $279.81 | $5.34 – $8.84 |
| Uchicago Medicine Adventhealth Glenoaks | Glendale Heights, IL | $279.81 | $5.46 – $8.84 |
| UPMC Community Osteopathic | Harrisburg, PA | $378.00 | $5.41 – $267.75 |
| UPMC Somerset | Somerset, PA | $378.00 | $5.41 – $5.46 |
| UPMC Carlisle | Carlisle, PA | $378.00 | $5.41 – $267.75 |
| UPMC Hanover | Hanover, PA | $378.00 | $5.41 – $8.74 |
| UPMC Lititz | Lititz, PA | $378.00 | $5.41 – $8.74 |
| UPMC Memorial | York, PA | $378.00 | $5.46 – $8.74 |
| RESEARCH PSYCHIATRIC CENTER | Kansas City, MO | not published | $5.14 – $5.14 |
| OVERLAND PARK REGIONAL MEDICAL CENTER | SHAWNEE, KS | not published | $5.14 – $8.48 |
| MENORAH MEDICAL CENTER | Overland Park, KS | not published | $5.14 – $8.48 |
| LEE'S SUMMIT MEDICAL CENTER | Lee's Summit, MO | not published | $5.14 – $8.48 |
| CENTERPOINT MEDICAL CENTER | Independence, MO | not published | $5.14 – $8.48 |
| LAFAYETTE REGIONAL HEALTH CENTER | Lexington, MO | not published | $8.48 – $8.48 |
| HCA FLORIDA WOODMONT HOSPITAL | TAMARAC, FL | not published | $4.99 – $8.48 |
| HCA FLORIDA WESTSIDE HOSPITAL | PLANTATION, FL | not published | $4.99 – $8.48 |
| HCA FLORIDA OCALA HOSPITAL | SUMMERFIELD, FL | not published | $4.99 – $15.42 |
| HCA FLORIDA SOUTH TAMPA HOSPITAL | Tampa, FL | not published | $4.99 – $11.05 |
| HCA FLORIDA UNIVERSITY HOSPITAL | Davie, FL | not published | $8.48 – $8.48 |
| UCF LAKE NONA HOSPITAL | Orlando, FL | not published | $4.99 – $15.42 |
| HCA FLORIDA TWIN CITIES HOSPITAL | DEFUNIAK SPRINGS, FL | not published | $4.99 – $15.42 |
| HCA FLORIDA TRINITY HOSPITAL | TRINITY, FL | not published | $4.99 – $11.05 |
| HCA FLORIDA ST. PETERSBURG HOSPITAL | NORTH, FL | not published | $4.99 – $11.05 |
| HCA FLORIDA ST. LUCIE HOSPITAL | STUART, FL | not published | $4.99 – $8.48 |
| HCA FLORIDA SOUTH SHORE HOSPITAL | PARRISH, FL | not published | $4.99 – $5.14 |
| HCA FLORIDA SARASOTA DOCTORS HOSPITAL | VENICE, FL | not published | $4.99 – $11.05 |
| HCA FLORIDA PUTNAM HOSPITAL | Palatka, FL | not published | $4.99 – $15.42 |
| HCA FLORIDA PALMS WEST HOSPITAL | LOXAHATCHEE, FL | not published | $4.99 – $8.48 |
| OVIEDO MEDICAL CENTER | Oviedo, FL | not published | $4.99 – $15.42 |
| HCA FLORIDA OSCEOLA HOSPITAL | ORLANDO, FL | not published | $4.99 – $15.42 |
| HCA FLORIDA OAK HILL HOSPITAL | BROOKSVILLE, FL | not published | $4.99 – $11.05 |
| HCA FLORIDA NORTHWEST HOSPITAL | MARGATE, FL | not published | $4.99 – $8.48 |
| HCA FLORIDA NORTHSIDE HOSPITAL | ST PETERSBURG, FL | not published | $4.99 – $5.14 |
| HCA FLORIDA NORTH FLORIDA HOSPITAL | NEWBERRY, FL | not published | $4.99 – $15.42 |
| HCA FLORIDA MERCY HOSPITAL | MIAMI, FL | not published | $4.99 – $8.48 |
| HCA FLORIDA MEMORIAL HOSPITAL | JACKSONVILLE, FL | not published | $5.14 – $8.48 |
| HCA FLORIDA LEHIGH HOSPITAL | LEHIGH ACRES, FL | not published | $4.99 – $11.05 |
| HCA HealthONE SOUTH PARKER ER, A PART OF SKY RIDGE | PARKER, CO | not published | $4.99 – $15.42 |
| HCA FLORIDA LAKE MONROE HOSPITAL | SANFORD, FL | not published | $4.99 – $15.42 |
| HCA FLORIDA LAKE CITY HOSPITAL | LIVE OAK, FL | not published | $4.99 – $15.42 |
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