Alpha-1-proteinase inhibitor (human) 1,000 mg (+/-) IV solution cost at US hospitals

ALPHA-1-PROTEINASE INHIBITOR (HUMAN) 1,000 MG (+/-) IV SOLUTION · HCPCS J0256

$3.25

lowest cash price

$13.14

national median

$378.00

highest cash price

218

hospitals with a published cash price

Middle half of hospitals (25th–75th percentile) against the full range. The same procedure varies $3.25–$378.00 — the variation is the story.

Cheapest published cash price

$3.25

Baptist Hospital — MIAMI, FL

Most expensive published cash price

$378.00

UPMC Memorial — York, PA

Median cash price over time

Sep 1, 2025 ($71.68) → Sep 1, 2026 ($4.94)

By state

State Hospitals Lowest cash Median Highest
Alaska 1 not published by hospital not published by hospital not published by hospital
Arizona 1 $7.26 $7.26 $7.26
California 52 $3.98 $4.28 $19.69
Colorado 11 $53.00 $53.00 $135.53
Florida 53 $3.25 $3.25 $49.75
Georgia 19 $13.53 $13.53 $13.53
Hawaii 1 $5.74 $5.74 $5.74
Illinois 27 $9.62 $38.29 $279.81
Iowa 18 $9.56 $9.76 $48.76
Kansas 5 not published by hospital not published by hospital not published by hospital
Kentucky 10 $3.60 $114.82 $157.78
Louisiana 6 not published by hospital not published by hospital not published by hospital
Maine 3 $71.68 $71.68 $71.68
Maryland 1 not published by hospital not published by hospital not published by hospital
Michigan 17 $7.41 $7.41 $7.41
Minnesota 8 not published by hospital not published by hospital not published by hospital
Missouri 14 not published by hospital not published by hospital not published by hospital
Montana 1 not published by hospital not published by hospital not published by hospital
Nebraska 7 $41.79 $41.79 $84.58
New Jersey 21 $4.94 $5.19 $5.19
New Mexico 2 not published by hospital not published by hospital not published by hospital
New York 19 $4.94 $4.94 $36.00
North Carolina 13 $22.78 $22.78 $22.78
North Dakota 2 not published by hospital not published by hospital not published by hospital
Ohio 29 $10.15 $10.15 $10.15
Oklahoma 8 $13.14 $13.14 $13.14
Oregon 4 $6.51 $6.51 $6.51
Pennsylvania 21 $29.80 $51.00 $378.00
South Carolina 8 not published by hospital not published by hospital not published by hospital
South Dakota 5 not published by hospital not published by hospital not published by hospital
Tennessee 9 not published by hospital not published by hospital not published by hospital
Texas 82 $5.52 $18.72 $26.25
Virginia 21 not published by hospital not published by hospital not published by hospital
Washington 12 $7.36 $7.45 $10.46
West Virginia 1 $3.60 $3.60 $3.60
Wisconsin 23 $6.53 $9.62 $17.07

All hospitals

Hospital Location Cash price Negotiated range
HSHS St. Joseph's Hospital HIGHLAND, IL $20.42 $8.86 – $2,664.74
HSHS St. Francis Hospital LITCHFIELD, IL $20.71 $8.86 – $1,721.15
Boca Raton Regional Hospital BOCA RATON, FL $20.83 $5.46 – $31.88
Atrium Health Anson Wadesboro, NC $22.78 $5.57 – $43.23
Atrium Health Mercy Charlotte, NC $22.78 $5.42 – $41.86
Atrium Health Pineville Charlotte, NC $22.78 $4.55 – $41.86
Atrium Health Stanly Albermarle, NC $22.78 $5.46 – $43.68
Atrium Health Behavioral Health Charlotte Charlotte, NC $22.78 $8.65 – $45.50
Atrium Health Cleveland Shelby, NC $22.78 $5.57 – $43.23
Atrium Health Cabarrus Concord, NC $22.78 $5.57 – $43.23
Atrium Health Lincoln Lincolnton, NC $22.78 $5.13 – $43.23
Atrium Health Union Monroe, NC $22.78 $5.57 – $43.23
Carolinas Rehabilitation Charlotte Charlotte, NC $22.78 $5.57 – $41.86
Atrium Health University City Charlotte, NC $22.78 $4.55 – $41.86
Atrium Health Carolinas Medical Center Charlotte, NC $22.78 $5.42 – $40.95
Dell Children's Medical Center (Ascension Seton) Austin, TX $26.25 $4.45 – $19.48
UPMC Muncy Muncy, PA $29.80 $5.46 – $6.00
UPMC Wellsboro Wellsboro, PA $29.80 $5.46 – $6.00
UPMC Williamsport Williamsport, PA $29.80 $5.46 – $5.84
HCA FLORIDA ORANGE PARK HOSPITAL MIDDLEBURG, FL $32.40 $5.14 – $8.48
UPMC Chautauqua Jamestown, NY $36.00 $4.50 – $40.50
UPMC Altoona Altoona, PA $36.00 $3.45 – $36.00
MercyOne Genesis Davenport Medical Center Davenport, IA $38.29 $4.97 – $7.27
MercyOne Genesis Silvis Medical Center Silvis, IL $38.29 $5.41 – $43.92
MercyOne Genesis DeWitt Medical Center DeWitt, IA $38.29 $17.16 – $36.85
MercyOne Genesis Aledo Medical Center Aledo, IL $38.29 $5.19 – $23.73
MercyOne Genesis Davenport West Medical Center Davenport, IA $38.29 $5.19 – $7.27
UPMC East Monroeville, PA $38.40 $3.45 – $38.40
UPMC Horizon-Greenville Greenville, PA $40.40 $3.45 – $10.25
UPMC Mercy Pittsburgh, PA $40.40 $3.45 – $7.25
UPMC Northwest Seneca, PA $40.40 $3.45 – $5.90
CHI Health Mercy Council Bluffs Council Bluffs, IA $41.79 $4.10 – $84.58
CHI Health Creighton University Medical Center - Bergan Mercy Omaha, NE $41.79 $4.10 – $84.58
Lasting Hope Recovery Center Omaha, NE $41.79 $5.20 – $84.58
CHI Health Immanuel Omaha, NE $41.79 $4.10 – $84.58
CHI Health Lakeside Omaha, NE $41.79 $4.10 – $84.58
CHI Health Midlands Papillion, NE $41.79 $4.10 – $84.58
UPMC Hamot Erie, PA $43.40 $3.45 – $6.75
CHI Health Mercy Corning Corning, IA $47.76 $4.91 – $97.51
CHI Health Missouri Valley Missouri Valley, IA $48.76 $4.91 – $97.51
HCA FLORIDA BLAKE HOSPITAL BRADENTON, FL $49.75 $4.99 – $11.05
UPMC Jameson New Castle, PA $51.00 $3.45 – $7.38
UPMC St. Margaret Pittsburgh, PA $51.00 $3.45 – $7.32
CENTRAL PARK ER, A PART OF ROSE DENVER, CO $53.00 $5.84 – $15.42
UPMC Magee Pittsburgh, PA $59.40 $3.45 – $7.32
UPMC Passavant-McCandless Pittsburgh, PA $59.40 $3.45 – $7.32
UPMC Presbyterian Pittsburgh, PA $59.40 $3.45 – $7.32
UPMC Western Psychiatric Pittsburgh, PA $59.40 $5.46 – $7.17
Lincoln Health Damariscotta, ME $71.68 $4.83 – $67.38
CHI Health Plainview Plainview, NE $83.58 $60.70 – $134.75

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