Alpha-1-proteinase inhibitor (human) 1,000 mg (+/-) IV solution cost at US hospitals
ALPHA-1-PROTEINASE INHIBITOR (HUMAN) 1,000 MG (+/-) IV SOLUTION · HCPCS J0256
$3.25
lowest cash price
$13.14
national median
$378.00
highest cash price
218
hospitals with a published cash price
Middle half of hospitals (25th–75th percentile) against the full range. The same procedure varies $3.25–$378.00 — the variation is the story.
Median cash price over time
Sep 1, 2025 ($71.68) → Sep 1, 2026 ($4.94)
By state
| State | Hospitals | Lowest cash | Median | Highest |
|---|---|---|---|---|
| Alaska | 1 | not published by hospital | not published by hospital | not published by hospital |
| Arizona | 1 | $7.26 | $7.26 | $7.26 |
| California | 52 | $3.98 | $4.28 | $19.69 |
| Colorado | 11 | $53.00 | $53.00 | $135.53 |
| Florida | 53 | $3.25 | $3.25 | $49.75 |
| Georgia | 19 | $13.53 | $13.53 | $13.53 |
| Hawaii | 1 | $5.74 | $5.74 | $5.74 |
| Illinois | 27 | $9.62 | $38.29 | $279.81 |
| Iowa | 18 | $9.56 | $9.76 | $48.76 |
| Kansas | 5 | not published by hospital | not published by hospital | not published by hospital |
| Kentucky | 10 | $3.60 | $114.82 | $157.78 |
| Louisiana | 6 | not published by hospital | not published by hospital | not published by hospital |
| Maine | 3 | $71.68 | $71.68 | $71.68 |
| Maryland | 1 | not published by hospital | not published by hospital | not published by hospital |
| Michigan | 17 | $7.41 | $7.41 | $7.41 |
| Minnesota | 8 | not published by hospital | not published by hospital | not published by hospital |
| Missouri | 14 | not published by hospital | not published by hospital | not published by hospital |
| Montana | 1 | not published by hospital | not published by hospital | not published by hospital |
| Nebraska | 7 | $41.79 | $41.79 | $84.58 |
| New Jersey | 21 | $4.94 | $5.19 | $5.19 |
| New Mexico | 2 | not published by hospital | not published by hospital | not published by hospital |
| New York | 19 | $4.94 | $4.94 | $36.00 |
| North Carolina | 13 | $22.78 | $22.78 | $22.78 |
| North Dakota | 2 | not published by hospital | not published by hospital | not published by hospital |
| Ohio | 29 | $10.15 | $10.15 | $10.15 |
| Oklahoma | 8 | $13.14 | $13.14 | $13.14 |
| Oregon | 4 | $6.51 | $6.51 | $6.51 |
| Pennsylvania | 21 | $29.80 | $51.00 | $378.00 |
| South Carolina | 8 | not published by hospital | not published by hospital | not published by hospital |
| South Dakota | 5 | not published by hospital | not published by hospital | not published by hospital |
| Tennessee | 9 | not published by hospital | not published by hospital | not published by hospital |
| Texas | 82 | $5.52 | $18.72 | $26.25 |
| Virginia | 21 | not published by hospital | not published by hospital | not published by hospital |
| Washington | 12 | $7.36 | $7.45 | $10.46 |
| West Virginia | 1 | $3.60 | $3.60 | $3.60 |
| Wisconsin | 23 | $6.53 | $9.62 | $17.07 |
All hospitals
| Hospital | Location | Cash price | Negotiated range |
|---|---|---|---|
| HSHS St. Joseph's Hospital | HIGHLAND, IL | $20.42 | $8.86 – $2,664.74 |
| HSHS St. Francis Hospital | LITCHFIELD, IL | $20.71 | $8.86 – $1,721.15 |
| Boca Raton Regional Hospital | BOCA RATON, FL | $20.83 | $5.46 – $31.88 |
| Atrium Health Anson | Wadesboro, NC | $22.78 | $5.57 – $43.23 |
| Atrium Health Mercy | Charlotte, NC | $22.78 | $5.42 – $41.86 |
| Atrium Health Pineville | Charlotte, NC | $22.78 | $4.55 – $41.86 |
| Atrium Health Stanly | Albermarle, NC | $22.78 | $5.46 – $43.68 |
| Atrium Health Behavioral Health Charlotte | Charlotte, NC | $22.78 | $8.65 – $45.50 |
| Atrium Health Cleveland | Shelby, NC | $22.78 | $5.57 – $43.23 |
| Atrium Health Cabarrus | Concord, NC | $22.78 | $5.57 – $43.23 |
| Atrium Health Lincoln | Lincolnton, NC | $22.78 | $5.13 – $43.23 |
| Atrium Health Union | Monroe, NC | $22.78 | $5.57 – $43.23 |
| Carolinas Rehabilitation Charlotte | Charlotte, NC | $22.78 | $5.57 – $41.86 |
| Atrium Health University City | Charlotte, NC | $22.78 | $4.55 – $41.86 |
| Atrium Health Carolinas Medical Center | Charlotte, NC | $22.78 | $5.42 – $40.95 |
| Dell Children's Medical Center (Ascension Seton) | Austin, TX | $26.25 | $4.45 – $19.48 |
| UPMC Muncy | Muncy, PA | $29.80 | $5.46 – $6.00 |
| UPMC Wellsboro | Wellsboro, PA | $29.80 | $5.46 – $6.00 |
| UPMC Williamsport | Williamsport, PA | $29.80 | $5.46 – $5.84 |
| HCA FLORIDA ORANGE PARK HOSPITAL | MIDDLEBURG, FL | $32.40 | $5.14 – $8.48 |
| UPMC Chautauqua | Jamestown, NY | $36.00 | $4.50 – $40.50 |
| UPMC Altoona | Altoona, PA | $36.00 | $3.45 – $36.00 |
| MercyOne Genesis Davenport Medical Center | Davenport, IA | $38.29 | $4.97 – $7.27 |
| MercyOne Genesis Silvis Medical Center | Silvis, IL | $38.29 | $5.41 – $43.92 |
| MercyOne Genesis DeWitt Medical Center | DeWitt, IA | $38.29 | $17.16 – $36.85 |
| MercyOne Genesis Aledo Medical Center | Aledo, IL | $38.29 | $5.19 – $23.73 |
| MercyOne Genesis Davenport West Medical Center | Davenport, IA | $38.29 | $5.19 – $7.27 |
| UPMC East | Monroeville, PA | $38.40 | $3.45 – $38.40 |
| UPMC Horizon-Greenville | Greenville, PA | $40.40 | $3.45 – $10.25 |
| UPMC Mercy | Pittsburgh, PA | $40.40 | $3.45 – $7.25 |
| UPMC Northwest | Seneca, PA | $40.40 | $3.45 – $5.90 |
| CHI Health Mercy Council Bluffs | Council Bluffs, IA | $41.79 | $4.10 – $84.58 |
| CHI Health Creighton University Medical Center - Bergan Mercy | Omaha, NE | $41.79 | $4.10 – $84.58 |
| Lasting Hope Recovery Center | Omaha, NE | $41.79 | $5.20 – $84.58 |
| CHI Health Immanuel | Omaha, NE | $41.79 | $4.10 – $84.58 |
| CHI Health Lakeside | Omaha, NE | $41.79 | $4.10 – $84.58 |
| CHI Health Midlands | Papillion, NE | $41.79 | $4.10 – $84.58 |
| UPMC Hamot | Erie, PA | $43.40 | $3.45 – $6.75 |
| CHI Health Mercy Corning | Corning, IA | $47.76 | $4.91 – $97.51 |
| CHI Health Missouri Valley | Missouri Valley, IA | $48.76 | $4.91 – $97.51 |
| HCA FLORIDA BLAKE HOSPITAL | BRADENTON, FL | $49.75 | $4.99 – $11.05 |
| UPMC Jameson | New Castle, PA | $51.00 | $3.45 – $7.38 |
| UPMC St. Margaret | Pittsburgh, PA | $51.00 | $3.45 – $7.32 |
| CENTRAL PARK ER, A PART OF ROSE | DENVER, CO | $53.00 | $5.84 – $15.42 |
| UPMC Magee | Pittsburgh, PA | $59.40 | $3.45 – $7.32 |
| UPMC Passavant-McCandless | Pittsburgh, PA | $59.40 | $3.45 – $7.32 |
| UPMC Presbyterian | Pittsburgh, PA | $59.40 | $3.45 – $7.32 |
| UPMC Western Psychiatric | Pittsburgh, PA | $59.40 | $5.46 – $7.17 |
| Lincoln Health | Damariscotta, ME | $71.68 | $4.83 – $67.38 |
| CHI Health Plainview | Plainview, NE | $83.58 | $60.70 – $134.75 |
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