Alteplase 100 mg infusion from pyxis vial at Sanford USD Medical Center

1305 W 18th St, Sioux Falls, SD · Sanford Health · · NPI 1821017880

Source: hospital's published price file ↗ · Published Mar 4, 2026 · Ingested Aug 12, 2026

$23,176.60

Cash price

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Discounted cash price

What a hospital charges a self-pay patient who pays directly, without going through insurance — usually well below the gross charge.

Example: A CT scan has a $3,200 gross charge but an $850 discounted cash price. Ask for it by name when scheduling — hospitals don't always advertise it up front.

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What you pay up front if you don't use insurance.

$28,970.75

Gross charge

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Gross charge (chargemaster price)

The hospital's full, undiscounted list price — pulled from its internal "chargemaster" price list. Almost no one actually pays this.

Example: A chest X-ray has a gross charge of $1,450. The same hospital's discounted cash price for the same X-ray is $180 — the gross charge mostly anchors negotiations, not what patients pay.

Full explanation →

The hospital's undiscounted list price — almost no one pays this.

$89.16 with Blue Cross Blue Shield of Minnesota vs $386.91 with First Choice Health Network — same scan, same building. Share

Negotiated rates by payer
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Negotiated rate

The price a specific insurance plan agreed to pay the hospital for a service — it varies by insurer, and even by plan within the same insurer.

Example: The same knee MRI has a negotiated rate of $904 with one insurer's PPO plan and $1,509 with another's — identical hospital, identical scan.

Full explanation →

Payer
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Payer

The insurance company footing the bill — Aetna, UnitedHealthcare, Medicare, and so on.

Example: "Blue Cross Blue Shield" is the payer. Its negotiated rate for an MRI might be $904, while a different payer's negotiated rate for the same scan is $1,509.

Full explanation →
Plan
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Plan

The specific product an insurer sells — e.g. "Blue Cross PPO 500" — which sets your deductible, coinsurance and negotiated rates.

Example: Two people both insured by Aetna can owe very different amounts for the same MRI: $50 with an HMO plan's flat copay, or the full $1,200 toward a high-deductible PPO plan's unmet deductible.

Full explanation →
Negotiated rate vs. cash
Blue Cross Blue Shield of Minnesota State Employees $89.16 ↓ -100%
Blue Cross Blue Shield of Minnesota Commercial $89.16 ↓ -100%
Blue Cross Blue Shield of Minnesota PMAP $89.16 ↓ -100%
Sanford Health Plan Align Medicare Replacement $89.72 ↓ -100%
Ucare Medicare Replacement $96.34 ↓ -100%
Health Partners Medicare Replacement $97.28 ↓ -100%
United Healthcare Medicare Replacement $97.28 ↓ -100%
Blue Cross Blue Shield of Minnesota Medicare Replacement $97.28 ↓ -100%
Great Plains Medicare Advantage Medicare Replacement $97.28 ↓ -100%
Aetna Medicare Replacement $97.28 ↓ -100%
Primewest Medicare Replacement $99.17 ↓ -100%
Sanford Health Plan SD Exchange Commercial $103.36 ↓ -100%
Sanford Health Plan Group Health/True $103.36 ↓ -100%
Sanford Health Plan Commercial/ND Pers $103.36 ↓ -100%
Sanford Health Plan SD Exchange True $103.36 ↓ -100%
Health Partners State Employees $144.02 ↓ -99%
Health Partners Commercial $167.66 ↓ -99%
Security Health Plan Commercial $236.45 ↓ -99%
United Healthcare CSP Top 20 $289.32 ↓ -99%
Medica Choice $289.75 ↓ -99%
Ucare Commercial $302.18 ↓ -99%
Medica Elect $309.96 ↓ -99%
Aetna Commercial $328.87 ↓ -99%
United Healthcare Commercial $378.74 ↓ -98%
Multiplan Commercial $386.91 ↓ -98%
Healthez Commercial $386.91 ↓ -98%
First Choice Health Network Commercial $386.91 ↓ -98%
Wellmark HMO/PPO not published by hospital —
Primewest Medicaid Managed Care not published by hospital —
Ucare Medicaid Managed Care not published by hospital —

Visitor-reported prices

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Alteplase 100 mg infusion from pyxis vial at other South-dakota hospitals

Hospital City Cash price Negotiated range
Sanford Clear Lake Medical Center Clear Lake $12,473.57 $164.03 – $287.77
Sanford Chamberlain Medical Center Chamberlain $12,850.08 $109.35 – $287.77
Sanford Vermillion Hospital Vermillion $12,473.57 $118.30 – $360.90
Sanford Aberdeen Medical Center Aberdeen not published $89.72 – $99.17

All South-dakota hospitals for this procedure →