Vutrisiran 25 mg/0.5 ml subcutaneous syringe cost at US hospitals

VUTRISIRAN 25 MG/0.5 ML SUBCUTANEOUS SYRINGE · HCPCS J0225

$4,983.86

lowest cash price

$13,248.60

national median

$143,221.20

highest cash price

hospitals with a published cash price

Middle half of hospitals (25th–75th percentile) against the full range. The same procedure varies $4,983.86–$143,221.20 — the variation is the story.

Cheapest published cash price

$4,983.86

Most expensive published cash price

$143,221.20

Median cash price over time

Dec 1, 2025 ($4,983.86) → Mar 1, 2026 ($13,248.60)

State	Hospitals	Lowest cash	Median	Highest
New Jersey	1	$4,983.86	$4,983.86	$4,983.86
Ohio	6	not published by hospital	not published by hospital	not published by hospital
Pennsylvania	4	$9,373.80	$13,248.60	$143,221.20

Hospital	Location	Cash price	Negotiated range
JFK Johnson Rehabilitation Institute (JRI)	Edison, NJ	$4,983.86	$4,236.28 – $6,580.02
UPMC Northwest	Seneca, PA	$9,373.80	$3,159.30 – $13,279.55
UPMC Presbyterian	Pittsburgh, PA	$13,248.60	$2,126.09 – $18,768.85
UPMC Passavant-McCandless	Pittsburgh, PA	$14,044.20	$2,126.09 – $13,279.55
UPMC Somerset	Somerset, PA	$143,221.20	$2,084.74 – $179,026.50
University Hospitals Cleveland Medical Center	Cleveland OH 44106\|3999 Richmond Road, OH	not published	$5,019.27 – $9,034.69
University Hospitals Portage Medical Center	Ravenna OH 44266, OH	not published	$5,019.27 – $9,034.69
University Hospitals Parma Medical Center	Parma OH 44129\|7007 Powers Boulevard, OH	not published	$5,019.27 – $9,034.69
University Hospitals Lake West Medical Center	Willoughby OH 44094\|7590 Auburn Road, OH	not published	$5,019.27 – $9,034.69
University Hospitals St. John Medical Center	Westlake OH, OH	not published	$8,372.87 – $17,043.32
University Hospitals Geneva Medical Center	Geneva, OH	not published	$16,092.85 – $17,043.32