Topotecan 4 mg/4 ml (1 mg/ml) intravenous solution cost at US hospitals
TOPOTECAN 4 MG/4 ML (1 MG/ML) INTRAVENOUS SOLUTION · HCPCS J9351
$17.26
lowest cash price
$316.84
national median
$3,358.00
highest cash price
451
hospitals with a published cash price
Middle half of hospitals (25th–75th percentile) against the full range. The same procedure varies $17.26–$3,358.00 — the variation is the story.
Median cash price over time
Sep 1, 2025 ($638.70) → Sep 1, 2026 ($342.17)
By state
| State | Hospitals | Lowest cash | Median | Highest |
|---|---|---|---|---|
| Alaska | 2 | $792.18 | $792.18 | $792.18 |
| Arizona | 3 | $316.84 | $430.90 | $589.67 |
| Arkansas | 3 | $194.25 | $246.05 | $325.00 |
| California | 67 | $19.71 | $267.29 | $3,358.00 |
| Colorado | 11 | $310.78 | $310.78 | $2,269.47 |
| Florida | 55 | $21.45 | $210.38 | $2,869.00 |
| Georgia | 24 | $25.49 | $25.49 | $1,253.88 |
| Hawaii | 1 | $357.99 | $357.99 | $357.99 |
| Illinois | 28 | $17.26 | $630.00 | $1,977.15 |
| Indiana | 19 | $114.92 | $200.93 | $1,292.18 |
| Iowa | 30 | $30.64 | $188.75 | $643.90 |
| Kansas | 5 | $298.27 | $298.27 | $490.00 |
| Kentucky | 15 | $218.64 | $308.58 | $1,292.18 |
| Louisiana | 6 | not published by hospital | not published by hospital | not published by hospital |
| Maine | 7 | $630.94 | $638.70 | $676.16 |
| Maryland | 1 | not published by hospital | not published by hospital | not published by hospital |
| Michigan | 13 | not published by hospital | not published by hospital | not published by hospital |
| Minnesota | 14 | $360.04 | $1,854.89 | $2,164.04 |
| Mississippi | 7 | $259.00 | $297.85 | $518.00 |
| Missouri | 16 | $169.60 | $312.65 | $381.89 |
| Montana | 2 | $384.16 | $384.16 | $497.65 |
| Nebraska | 12 | $58.90 | $268.89 | $544.17 |
| Nevada | 2 | $329.85 | $329.85 | $365.25 |
| New Hampshire | 1 | $1,425.12 | $1,425.12 | $1,425.12 |
| New Jersey | 21 | not published by hospital | not published by hospital | not published by hospital |
| New Mexico | 1 | not published by hospital | not published by hospital | not published by hospital |
| New York | 21 | $124.95 | $124.95 | $129.60 |
| North Carolina | 14 | $76.53 | $2,176.33 | $2,176.33 |
| North Dakota | 2 | $195.53 | $195.53 | $772.40 |
| Ohio | 53 | $20.90 | $517.65 | $931.45 |
| Oklahoma | 10 | $28.64 | $28.64 | $559.64 |
| Oregon | 11 | $201.34 | $405.72 | $730.29 |
| Pennsylvania | 18 | $17.40 | $141.00 | $702.00 |
| South Carolina | 8 | $690.03 | $690.03 | $789.79 |
| South Dakota | 1 | $546.96 | $546.96 | $546.96 |
| Tennessee | 22 | $259.00 | $305.23 | $403.80 |
| Texas | 97 | $22.86 | $507.60 | $2,581.93 |
| Virginia | 19 | $191.12 | $523.76 | $2,785.00 |
| Washington | 23 | $42.16 | $393.65 | $1,114.38 |
| West Virginia | 5 | $32.54 | $56.80 | $73.78 |
| Wisconsin | 23 | $22.30 | $22.30 | $134.57 |
All hospitals
| Hospital | Location | Cash price | Negotiated range |
|---|---|---|---|
| Swedish Medical Center - First Hill Campus | Seattle, WA | $393.65 | $0.55 – $3.07 |
| Swedish Edmonds Hospital | Edmonds, WA | $393.65 | $0.55 – $3.07 |
| AdventHealth Orlando | Orlando, FL | $402.33 | not published |
| Holston Valley Medical Center | KINGSPORT, TN | $403.80 | $4.47 – $5.00 |
| Mansfield Hospital | Mansfield, OH | $404.20 | $2.28 – $11.57 |
| Grady Memorial Hospital | Delaware, OH | $404.20 | $3.03 – $11.57 |
| Grant Medical Center | Columbus, OH | $404.20 | $3.03 – $4.82 |
| Sunnyside Medical Center | CLACKAMAS, OR | $405.72 | $1.34 – $1.34 |
| Westside Medical Center | HILLSBORO, OR | $405.72 | $1.34 – $1.34 |
| Mercy Hospital Ardmore | Northwest Ardmore, OK | $416.00 | $46.49 – $238.80 |
| St Anne Hospital | Toledo, OH | $418.92 | not published |
| St. Joseph’s Hospital and Medical Center | Phoenix, AZ | $430.90 | $1.57 – $891.12 |
| Hazard ARH Regional Medical Center | Hazard, KY | $456.00 | $1.59 – $1.59 |
| Sanford Thief River Falls Medical Center | Thief River Falls, MN | $475.71 | $127.08 – $332.96 |
| Sanford Behavioral Health Thief River Falls | Thief River Falls, MN | $475.71 | $127.08 – $332.96 |
| Sanford Luverne Medical Center | Luverne, MN | $487.56 | $147.55 – $548.50 |
| OVERLAND PARK REGIONAL MEDICAL CENTER | SHAWNEE, KS | $490.00 | $1.25 – $2.11 |
| Providence Holy Cross Medical Center | Mission Hills, CA | $493.59 | $2.53 – $120.08 |
| Providence Saint Joseph Medical Center | Burbank, CA | $493.59 | $2.27 – $104.31 |
| St Patrick Hospital - Broadway Campus | Missoula, MT | $497.65 | $2.28 – $4.14 |
| Texas Health Harris Methodist Hospital Alliance | Fort Worth, TX | $507.60 | $3.08 – $3.08 |
| Texas Health Arlington Memorial Hospital | Arlington, TX | $507.60 | $3.08 – $3.08 |
| Texas Health Presbyterian Hospital Allen | Allen, TX | $507.60 | $3.08 – $3.08 |
| Texas Health Center for Diagnostics and Surgery Plano | Plano, TX | $507.60 | $4.83 – $4.83 |
| Texas Health Harris Methodist Hospital Azle | Azle, TX | $507.60 | $4.83 – $4.83 |
| Texas Health Presbyterian Hospital Flower Mound | Flower Mound, TX | $507.60 | $4.83 – $4.83 |
| Texas Health Presbyterian Hospital Denton | Denton, TX | $507.60 | $3.08 – $3.08 |
| Texas Health Presbyterian Hospital Dallas | Dallas, TX | $507.60 | $3.08 – $3.08 |
| Texas Health Hospital Frisco | Frisco, TX | $507.60 | $3.08 – $3.08 |
| Texas Health Heart & Vascular Hospital Arlington | Arlington, TX | $507.60 | $4.83 – $4.83 |
| Texas Health Presbyterian Hospital Kaufman | Kaufman, TX | $507.60 | $4.83 – $4.83 |
| Texas Health Harris Methodist Hospital Hurst-Euless-Bedford | Bedford, TX | $507.60 | $3.08 – $3.08 |
| Texas Health Presbyterian Hospital Plano | Plano, TX | $507.60 | $3.08 – $3.08 |
| Texas Health Hospital Rockwall | Rockwall, TX | $507.60 | $4.83 – $4.83 |
| Texas Health Harris Methodist Hospital Southlake | Southlake, TX | $507.60 | $4.83 – $4.83 |
| Texas Health Springwood Hospital Hurst-Euless-Bedford | Bedford, TX | $507.60 | $3.08 – $3.08 |
| Texas Health Harris Methodist Hospital Southwest Fort Worth | Fort Worth, TX | $507.60 | $3.08 – $3.08 |
| Texas Health Harris Methodist Hospital Fort Worth | Fort Worth, TX | $507.60 | $3.08 – $3.08 |
| Texas Health Harris Methodist Hospital Stephenville | Stephenville, TX | $507.60 | $4.83 – $4.83 |
| Texas Health Harris Methodist Hospital Cleburne | Cleburne, TX | $507.60 | $4.83 – $4.83 |
| University Hospitals Beachwood Medical Center | Beachwood, OH | $517.65 | $45.28 – $101.88 |
| University Hospitals Conneaut Medical Center | Conneaut, OH | $517.65 | $4.68 – $4.68 |
| University Hospitals Elyria Medical Center | Elyria, OH | $517.65 | $2.61 – $2.61 |
| University Hospitals Geneva Medical Center | Geneva, OH | $517.65 | $4.33 – $4.33 |
| University Hospitals St. John Medical Center | Westlake OH, OH | $517.65 | $2.25 – $12.50 |
| University Hospitals Samaritan Medical Center | Ashland, OH | $517.65 | $3.26 – $7.02 |
| University Hospitals Lake West Medical Center | Willoughby OH 44094|7590 Auburn Road, OH | $517.65 | not published |
| University Hospitals Parma Medical Center | Parma OH 44129|7007 Powers Boulevard, OH | $517.65 | $2.55 – $2.55 |
| University Hospitals Portage Medical Center | Ravenna OH 44266, OH | $517.65 | $3.45 – $3.45 |
| University Hospitals Cleveland Medical Center | Cleveland OH 44106|3999 Richmond Road, OH | $517.65 | $5.33 – $7.02 |
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