Topotecan 4 mg/4 ml (1 mg/ml) intravenous solution cost at US hospitals
TOPOTECAN 4 MG/4 ML (1 MG/ML) INTRAVENOUS SOLUTION · HCPCS J9351
$17.26
lowest cash price
$316.84
national median
$3,358.00
highest cash price
451
hospitals with a published cash price
Middle half of hospitals (25th–75th percentile) against the full range. The same procedure varies $17.26–$3,358.00 — the variation is the story.
Median cash price over time
Sep 1, 2025 ($638.70) → Sep 1, 2026 ($342.17)
By state
| State | Hospitals | Lowest cash | Median | Highest |
|---|---|---|---|---|
| Alaska | 2 | $792.18 | $792.18 | $792.18 |
| Arizona | 3 | $316.84 | $430.90 | $589.67 |
| Arkansas | 3 | $194.25 | $246.05 | $325.00 |
| California | 67 | $19.71 | $267.29 | $3,358.00 |
| Colorado | 11 | $310.78 | $310.78 | $2,269.47 |
| Florida | 55 | $21.45 | $210.38 | $2,869.00 |
| Georgia | 24 | $25.49 | $25.49 | $1,253.88 |
| Hawaii | 1 | $357.99 | $357.99 | $357.99 |
| Illinois | 28 | $17.26 | $630.00 | $1,977.15 |
| Indiana | 19 | $114.92 | $200.93 | $1,292.18 |
| Iowa | 30 | $30.64 | $188.75 | $643.90 |
| Kansas | 5 | $298.27 | $298.27 | $490.00 |
| Kentucky | 15 | $218.64 | $308.58 | $1,292.18 |
| Louisiana | 6 | not published by hospital | not published by hospital | not published by hospital |
| Maine | 7 | $630.94 | $638.70 | $676.16 |
| Maryland | 1 | not published by hospital | not published by hospital | not published by hospital |
| Michigan | 13 | not published by hospital | not published by hospital | not published by hospital |
| Minnesota | 14 | $360.04 | $1,854.89 | $2,164.04 |
| Mississippi | 7 | $259.00 | $297.85 | $518.00 |
| Missouri | 16 | $169.60 | $312.65 | $381.89 |
| Montana | 2 | $384.16 | $384.16 | $497.65 |
| Nebraska | 12 | $58.90 | $268.89 | $544.17 |
| Nevada | 2 | $329.85 | $329.85 | $365.25 |
| New Hampshire | 1 | $1,425.12 | $1,425.12 | $1,425.12 |
| New Jersey | 21 | not published by hospital | not published by hospital | not published by hospital |
| New Mexico | 1 | not published by hospital | not published by hospital | not published by hospital |
| New York | 21 | $124.95 | $124.95 | $129.60 |
| North Carolina | 14 | $76.53 | $2,176.33 | $2,176.33 |
| North Dakota | 2 | $195.53 | $195.53 | $772.40 |
| Ohio | 53 | $20.90 | $517.65 | $931.45 |
| Oklahoma | 10 | $28.64 | $28.64 | $559.64 |
| Oregon | 11 | $201.34 | $405.72 | $730.29 |
| Pennsylvania | 18 | $17.40 | $141.00 | $702.00 |
| South Carolina | 8 | $690.03 | $690.03 | $789.79 |
| South Dakota | 1 | $546.96 | $546.96 | $546.96 |
| Tennessee | 22 | $259.00 | $305.23 | $403.80 |
| Texas | 97 | $22.86 | $507.60 | $2,581.93 |
| Virginia | 19 | $191.12 | $523.76 | $2,785.00 |
| Washington | 23 | $42.16 | $393.65 | $1,114.38 |
| West Virginia | 5 | $32.54 | $56.80 | $73.78 |
| Wisconsin | 23 | $22.30 | $22.30 | $134.57 |
All hospitals
| Hospital | Location | Cash price | Negotiated range |
|---|---|---|---|
| Riverside Methodist Hospital | Columbus, OH | $173.55 | $3.03 – $4.82 |
| Marion General Hospital | Marion, OH | $173.55 | $3.03 – $11.57 |
| Adventhealth Riverview | Riverview, FL | $178.65 | not published |
| Adventhealth Wesley Chapel | Wesley Chapel, FL | $178.65 | not published |
| Adventhealth Hendersonville | Hendersonville, NC | $182.79 | not published |
| MercyOne Dubuque Medical Center | Dubuque, IA | $188.75 | $41.06 – $115.00 |
| MercyOne New Hampton Medical Center | New Hampton, IA | $188.75 | $45.53 – $115.00 |
| MercyOne Dyersville Medical Center | Dyersville, IA | $188.75 | $43.47 – $129.44 |
| MercyOne Clinton Medical Center | Clinton, IA | $188.75 | $32.55 – $115.00 |
| MercyOne Oelwein Medical Center | Oelwein, IA | $188.75 | $43.95 – $115.00 |
| MercyOne Cedar Falls Medical Center | Cedar Falls, IA | $188.75 | $27.03 – $115.00 |
| MercyOne Elkader Medical Center | Elkader, IA | $188.75 | $59.19 – $120.20 |
| MercyOne Centerville Medical Center | Centerville, IA | $188.75 | $31.56 – $115.00 |
| MercyOne Newton Medical Center | Newton, IA | $188.75 | $74.75 – $115.00 |
| MercyOne North Iowa Medical Center | Mason City, IA | $188.75 | $29.44 – $115.00 |
| Russell County Hospital | LEBANON, VA | $191.12 | $4.47 – $27.35 |
| Central Medical Center | Seattle, WA | $193.06 | $1.34 – $1.34 |
| 82-3844150 BMH Crittenden | West Memphis, AR | $194.25 | $1.61 – $36.47 |
| Sanford Medical Center Bismarck | Bismarck, ND | $195.53 | $69.60 – $197.55 |
| St Ritas Medical Center | Lima, OH | $196.20 | not published |
| St Jude Medical Center | Fullerton, CA | $197.84 | $2.08 – $50.05 |
| HCA HOUSTON CLEAR LAKE | FRIENDSWOOD, TX | $198.45 | $2.11 – $4.63 |
| Providence Mission Hospital - Mission Viejo | Mission Viejo, CA | $200.02 | $2.08 – $49.43 |
| Ascension St. Vincent Carmel Ambulatory Surgery Center | Carmel, IN | $200.93 | $0.78 – $8.15 |
| Ascension St. Vincent Evansville (St. Mary's Health, Inc.) | IN 47750|10388 Warrick Wellness Trail Newburgh, IN | $200.93 | $0.78 – $8.15 |
| Ascension St. Vincent Naab Surgery Center | Indianapolis, IN | $200.93 | $0.78 – $8.15 |
| Ascension St. Vincent Randolph (St. Vincent Randolph Hospital, Inc.) | Winchester, IN | $200.93 | $0.78 – $8.15 |
| Ascension St. Vincent Anderson (St. Vincent Anderson Regional Hospital, Inc.) | Anderson, IN | $200.93 | $0.78 – $8.15 |
| Ascension St. Vincent Mercy (St. Vincent Madison County Health System, Inc.) | Elwood, IN | $200.93 | $0.78 – $8.15 |
| Ascension St. Vincent Fishers (St. Vincent Fishers Hospital, Inc.) | Fishers, IN | $200.93 | $0.78 – $8.15 |
| Ascension St. Vincent Kokomo (St. Joseph Hospital & Health Center, Inc.) | Kokomo, IN | $200.93 | $0.78 – $8.15 |
| Ascension St. Vincent Carmel (St. Vincent Carmel Hospital, Inc.) | Carmel, IN | $200.93 | $0.78 – $8.15 |
| Providence St Vincent Medical Center | Portland, OR | $201.34 | $1.48 – $5.34 |
| Providence St Joseph Hospital Orange | Orange, CA | $209.51 | $2.08 – $48.82 |
| HCA FLORIDA NORTH FLORIDA HOSPITAL | NEWBERRY, FL | $210.38 | $2.05 – $6.33 |
| HCA FLORIDA KENDALL HOSPITAL | DORAL, FL | $212.10 | $2.05 – $3.48 |
| AdventHealth New Smyrna Beach | New Smyrna Beach, FL | $213.35 | not published |
| Richmond Community Hospital | Richmond, VA | $216.25 | not published |
| CHI Saint Joseph Health - Saint Joseph London | London, KY | $218.64 | $2.10 – $557.57 |
| CHI Saint Joseph Health - Saint Joseph Mount Sterling | Mt. Sterling, KY | $224.55 | $2.10 – $557.57 |
| Adventhealth Zephyrhills | Zephyrhills, FL | $232.01 | not published |
| Adventhealth Waterman | Tavares, FL | $240.29 | not published |
| Mercy Hospital Southeast | Cape Girardeau, MO | $240.84 | $91.20 – $91.20 |
| Providence Cedars-Sinai Tarzana Medical Center | Tarzana, CA | $241.05 | $2.53 – $104.10 |
| Providence Saint John's Health Center | Santa Monica, CA | $241.05 | $1.34 – $81.94 |
| Mercy West Hospital | Cincinnati, OH | $243.72 | not published |
| 26-1214372 NEA Baptist | Jonesboro, AR | $246.05 | $1.94 – $28.72 |
| CHI Saint Joseph Health - Saint Joseph East | Lexington, KY | $246.12 | $2.10 – $557.57 |
| Orange County Anaheim Medical Center | Anaheim, CA | $248.20 | $1.34 – $1.34 |
| Baldwin Park Medical Center | BALDWIN PARK, CA | $248.20 | $1.34 – $1.34 |
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- Acetylcysteine 200 mg/ml (20 %) intravenous solution from $12.60