Topotecan 4 mg/4 ml (1 mg/ml) intravenous solution cost at US hospitals
TOPOTECAN 4 MG/4 ML (1 MG/ML) INTRAVENOUS SOLUTION · HCPCS J9351
$17.26
lowest cash price
$316.84
national median
$3,358.00
highest cash price
451
hospitals with a published cash price
Middle half of hospitals (25th–75th percentile) against the full range. The same procedure varies $17.26–$3,358.00 — the variation is the story.
Median cash price over time
Sep 1, 2025 ($638.70) → Sep 1, 2026 ($342.17)
By state
| State | Hospitals | Lowest cash | Median | Highest |
|---|---|---|---|---|
| Alaska | 2 | $792.18 | $792.18 | $792.18 |
| Arizona | 3 | $316.84 | $430.90 | $589.67 |
| Arkansas | 3 | $194.25 | $246.05 | $325.00 |
| California | 67 | $19.71 | $267.29 | $3,358.00 |
| Colorado | 11 | $310.78 | $310.78 | $2,269.47 |
| Florida | 55 | $21.45 | $210.38 | $2,869.00 |
| Georgia | 24 | $25.49 | $25.49 | $1,253.88 |
| Hawaii | 1 | $357.99 | $357.99 | $357.99 |
| Illinois | 28 | $17.26 | $630.00 | $1,977.15 |
| Indiana | 19 | $114.92 | $200.93 | $1,292.18 |
| Iowa | 30 | $30.64 | $188.75 | $643.90 |
| Kansas | 5 | $298.27 | $298.27 | $490.00 |
| Kentucky | 15 | $218.64 | $308.58 | $1,292.18 |
| Louisiana | 6 | not published by hospital | not published by hospital | not published by hospital |
| Maine | 7 | $630.94 | $638.70 | $676.16 |
| Maryland | 1 | not published by hospital | not published by hospital | not published by hospital |
| Michigan | 13 | not published by hospital | not published by hospital | not published by hospital |
| Minnesota | 14 | $360.04 | $1,854.89 | $2,164.04 |
| Mississippi | 7 | $259.00 | $297.85 | $518.00 |
| Missouri | 16 | $169.60 | $312.65 | $381.89 |
| Montana | 2 | $384.16 | $384.16 | $497.65 |
| Nebraska | 12 | $58.90 | $268.89 | $544.17 |
| Nevada | 2 | $329.85 | $329.85 | $365.25 |
| New Hampshire | 1 | $1,425.12 | $1,425.12 | $1,425.12 |
| New Jersey | 21 | not published by hospital | not published by hospital | not published by hospital |
| New Mexico | 1 | not published by hospital | not published by hospital | not published by hospital |
| New York | 21 | $124.95 | $124.95 | $129.60 |
| North Carolina | 14 | $76.53 | $2,176.33 | $2,176.33 |
| North Dakota | 2 | $195.53 | $195.53 | $772.40 |
| Ohio | 53 | $20.90 | $517.65 | $931.45 |
| Oklahoma | 10 | $28.64 | $28.64 | $559.64 |
| Oregon | 11 | $201.34 | $405.72 | $730.29 |
| Pennsylvania | 18 | $17.40 | $141.00 | $702.00 |
| South Carolina | 8 | $690.03 | $690.03 | $789.79 |
| South Dakota | 1 | $546.96 | $546.96 | $546.96 |
| Tennessee | 22 | $259.00 | $305.23 | $403.80 |
| Texas | 97 | $22.86 | $507.60 | $2,581.93 |
| Virginia | 19 | $191.12 | $523.76 | $2,785.00 |
| Washington | 23 | $42.16 | $393.65 | $1,114.38 |
| West Virginia | 5 | $32.54 | $56.80 | $73.78 |
| Wisconsin | 23 | $22.30 | $22.30 | $134.57 |
All hospitals
| Hospital | Location | Cash price | Negotiated range |
|---|---|---|---|
| HSHS St. Mary's Hospital | DECATUR, IL | $17.26 | $2.06 – $23.64 |
| UPMC Williamsport | Williamsport, PA | $17.40 | $2.54 – $2.80 |
| UPMC Wellsboro | Wellsboro, PA | $17.40 | $2.54 – $2.80 |
| St. John's Camarillo Hospital | Camarillo, CA | $19.71 | $1.49 – $35.10 |
| Dublin Methodist Hospital | Dublin, OH | $20.90 | $3.03 – $4.82 |
| Doctors Hospital | Columbus, OH | $20.90 | $3.03 – $4.82 |
| Baptist Hospital | MIAMI, FL | $21.45 | $5.71 – $29.70 |
| Bethesda Hospital East | BOYNTON BEACH, FL | $21.45 | $7.96 – $33.00 |
| Doctors Hospital | CORAL GABLES, FL | $21.45 | $5.78 – $29.70 |
| Baptist Health Hospital Doral | SOUTH MIAMI, FL | $21.45 | $5.74 – $29.70 |
| Homestead Hospital | HOMESTEAD, FL | $21.45 | $5.61 – $29.70 |
| West Kendall Baptist Hospital | MIAMI, FL | $21.45 | $5.64 – $29.70 |
| HSHS St. Vincent Hospital | Green Bay, WI | $22.30 | $1.60 – $2.24 |
| Ascension Seton Northwest (Ascension Seton) | Austin, TX | $22.86 | $0.90 – $0.90 |
| Ascension Seton Medical Center Austin (Ascension Seton) | Austin, TX | $22.86 | $0.90 – $0.90 |
| Fishermens Community Hospital | MARATHON, FL | $23.40 | $6.01 – $32.40 |
| Mariners Hospital | TAVERNIER, FL | $23.40 | $6.23 – $32.40 |
| Emory Decatur Hospital | Decatur, GA | $25.49 | not published |
| Emory Hillandale Hospital | Lithonia, GA | $25.49 | not published |
| Emory Long-Term Acute Care Hospital | Decatur, GA | $25.49 | not published |
| Emory Johns Creek Hospital | Johns Creek, GA | $25.49 | not published |
| Emory Rehabilitation Hospital | Atlanta, GA | $25.49 | not published |
| Emory Saint Joseph's Hospital | Atlanta, GA | $25.49 | not published |
| Emory University Hospital | Ne, GA | $25.49 | not published |
| Emory University Hospital Midtown | Atlanta, GA | $25.49 | not published |
| Ascension St. John Medical Center (St. John Medical Center, Inc.) | Tulsa, OK | $28.64 | $19.78 – $19.78 |
| Ascension St. John Owasso (Owasso Medical Facility, Inc.) | Owasso, OK | $28.64 | $16.53 – $16.53 |
| Ascension St. John Jane Phillips (Jane Phillips Memorial Medical Center, Inc.) | Bartlesville, OK | $28.64 | $3.75 – $21.29 |
| Ascension St. John Nowata (Jane Phillips Nowata Hospital, Inc.) | Nowata, OK | $28.64 | $3.75 – $4.02 |
| Ascension St. John Sapulpa (St. John Sapulpa, Inc.) | Sapulpa, OK | $28.64 | $15.60 – $15.60 |
| UnityPoint Health - Allen Hospital | Waterloo, IA | $30.64 | $0.94 – $10.38 |
| Berkeley Medical Center | Martinsburg, WV | $32.54 | not published |
| Thomas Hospitals | South Charleston, WV | $34.06 | $1.29 – $1.29 |
| MultiCare Allenmore Hospital | Tacoma, WA | $42.16 | not published |
| UnityPoint Health - Iowa Lutheran Hospital | Des Moines, IA | $51.64 | $0.94 – $6.63 |
| Ascension Sacred Heart Pensacola (Sacred Heart Health System, Inc.) | Pensacola, FL | $54.40 | $2.10 – $5.89 |
| RIDEOUT MEMORIAL HOSPITAL | Marysville, CA | $55.21 | $1.02 – $311.18 |
| Camden Clark Medical Center | Parkersburg, WV | $56.80 | $2.06 – $2.06 |
| Uniontown Hospital | Uniontown, PA | $57.89 | $2.06 – $2.06 |
| CHI Health Nebraska Heart | Lincoln, NE | $58.90 | $1.64 – $9.00 |
| Grant Memorial Hospital | Petersburg, WV | $61.24 | not published |
| CHI Health St. Elizabeth | Lincoln, NE | $64.02 | $1.64 – $8.78 |
| Adventhealth Central Texas | Killeen, TX | $66.58 | $9.09 – $9.09 |
| Adventhealth Rollins Brook | Lampasas, TX | $66.58 | $9.09 – $9.09 |
| Parkview Bryan Hospital | Bryan, OH | $69.36 | not published |
| Parkview Montpelier Hospital | Montpelier, OH | $69.36 | not published |
| West Virginia University Hospitals | Morgantown, WV | $73.78 | $1.29 – $1.29 |
| CHI Health St. Francis | Grand Island, NE | $75.55 | $1.64 – $10.32 |
| AdventHealth Polk | Columbus, NC | $76.53 | $2.47 – $2.47 |
| MultiCare Yakima Memorial Hospital | Yakima, WA | $76.77 | $4.09 – $4.09 |
Related drugs procedures
- Abatacept (with maltose) 250 mg intravenous solution from $141.66
- Abciximab injection from $354.77
- Abobotulinumtoxina from $51.15
- Acetaminophen 10 mg/ml soln 100 ml glass cont from $3.00
- Acetazolamide 500 mg solution for injection from $6.30
- Acetylcysteine 200 mg/ml (20 %) intravenous solution from $12.60