Methylnaltrexone 12 mg/0.6 ml subcutaneous injection (wrapper) cost at US hospitals
METHYLNALTREXONE 12 MG/0.6 ML SUBCUTANEOUS INJECTION (WRAPPER) · HCPCS J2212
$18.83
lowest cash price
$407.16
national median
$3,078.69
highest cash price
542
hospitals with a published cash price
Middle half of hospitals (25th–75th percentile) against the full range. The same procedure varies $18.83–$3,078.69 — the variation is the story.
Median cash price over time
Sep 1, 2025 ($765.83) → Sep 1, 2026 ($752.97)
By state
| State | Hospitals | Lowest cash | Median | Highest |
|---|---|---|---|---|
| Alaska | 3 | $587.36 | $587.36 | $831.04 |
| Arizona | 6 | $282.30 | $386.22 | $620.32 |
| Arkansas | 3 | $188.16 | $192.20 | $216.26 |
| California | 84 | $64.55 | $329.09 | $1,005.96 |
| Colorado | 13 | $569.25 | $2,161.47 | $2,161.47 |
| Florida | 73 | $233.00 | $1,092.49 | $3,078.69 |
| Georgia | 16 | $198.95 | $792.56 | $2,612.30 |
| Hawaii | 2 | $182.71 | $182.71 | $440.75 |
| Illinois | 15 | $281.91 | $433.12 | $991.90 |
| Indiana | 22 | $308.40 | $308.40 | $1,812.47 |
| Iowa | 25 | $84.93 | $572.60 | $858.90 |
| Kansas | 6 | $263.01 | $2,207.81 | $2,207.81 |
| Kentucky | 18 | $203.13 | $678.30 | $1,812.47 |
| Louisiana | 5 | $469.75 | $469.75 | $469.75 |
| Maine | 7 | $581.42 | $765.83 | $1,658.49 |
| Maryland | 2 | $150.00 | $150.00 | $150.00 |
| Michigan | 18 | $112.26 | $112.26 | $112.26 |
| Minnesota | 15 | $48.55 | $299.46 | $349.37 |
| Missouri | 16 | $188.16 | $202.31 | $263.01 |
| Montana | 2 | $343.29 | $343.29 | $343.29 |
| Nebraska | 12 | $119.16 | $326.38 | $660.52 |
| Nevada | 2 | $169.95 | $169.95 | $188.19 |
| New Hampshire | 1 | $1,729.79 | $1,729.79 | $1,729.79 |
| New Jersey | 21 | not published by hospital | not published by hospital | not published by hospital |
| New Mexico | 2 | $831.04 | $831.04 | $1,199.72 |
| New York | 17 | not published by hospital | not published by hospital | not published by hospital |
| North Carolina | 14 | $392.75 | $392.75 | $776.12 |
| North Dakota | 2 | $67.20 | $67.20 | $118.20 |
| Ohio | 57 | $362.86 | $582.48 | $2,059.56 |
| Oklahoma | 7 | $303.47 | $303.47 | $466.88 |
| Oregon | 12 | $247.56 | $493.10 | $499.52 |
| Pennsylvania | 25 | $160.20 | $234.60 | $1,122.60 |
| South Carolina | 10 | $616.00 | $616.00 | $1,053.57 |
| South Dakota | 5 | $73.99 | $93.32 | $392.80 |
| Tennessee | 26 | $59.14 | $139.55 | $1,654.94 |
| Texas | 107 | $18.83 | $432.83 | $1,364.33 |
| Virginia | 19 | $139.55 | $752.97 | $1,189.51 |
| Washington | 25 | $221.07 | $303.21 | $1,409.74 |
| West Virginia | 5 | $165.68 | $331.36 | $351.16 |
| Wisconsin | 12 | $368.90 | $368.90 | $368.90 |
All hospitals
| Hospital | Location | Cash price | Negotiated range |
|---|---|---|---|
| Northwestern Medicine Palos Hospital | Palos Heights, IL | $433.12 | not published |
| Moanalua Medical Center | HONOLULU, HI | $440.75 | not published |
| WellSpan Chambersburg Hospital | Chambersburg, PA | $451.20 | $1.41 – $609.00 |
| WellSpan Waynesboro Hospital | Waynesboro, PA | $451.20 | $118.44 – $609.00 |
| Rappahannock General Hospital | Kilmarnock, VA | $462.22 | not published |
| Allen Hospital | Oberlin, OH | $462.24 | not published |
| Lorain Hospital | Lorain, OH | $462.24 | not published |
| Love County Health Center | Marietta, OK | $466.88 | $80.00 – $80.00 |
| CHRISTUS St. Francis Cabrini Hospital | Alexandria, LA | $469.75 | $1.22 – $1.80 |
| Jewish Hospital | Cincinnati, OH | $475.86 | not published |
| Adventhealth Hendersonville | Hendersonville, NC | $478.39 | not published |
| California Hospital Medical Center | Los Angeles, CA | $490.82 | $0.98 – $799.48 |
| Providence Seaside Hospital | Seaside, OR | $492.95 | not published |
| Providence Medford Medical Center | Medford, OR | $493.10 | not published |
| Providence Newberg Medical Center | Newberg, OR | $493.10 | not published |
| Providence Portland Medical Center | Portland, OR | $493.10 | $5.40 – $5.40 |
| Providence St Vincent Medical Center | Portland, OR | $493.10 | $5.40 – $5.40 |
| Providence Willamette Falls Medical Center | Oregon City, OR | $493.10 | $5.40 – $5.40 |
| Providence Milwaukie Hospital | Milwaukie, OR | $493.10 | $5.40 – $5.40 |
| Sunnyside Medical Center | CLACKAMAS, OR | $499.52 | not published |
| Westside Medical Center | HILLSBORO, OR | $499.52 | not published |
| UPMC Muncy | Muncy, PA | $504.60 | $0.90 – $5.40 |
| UPMC Wellsboro | Wellsboro, PA | $504.60 | not published |
| UPMC Williamsport | Williamsport, PA | $504.60 | not published |
| Southeastern Medical Center | Cambridge, OH | $507.10 | $8.71 – $8.71 |
| HCA FLORIDA SOUTH SHORE HOSPITAL | PARRISH, FL | $509.88 | $4.52 – $4.52 |
| Anderson Hospital | Cincinnati, OH | $511.20 | not published |
| Clermont Hospital | Batavia, OH | $511.20 | not published |
| Kings Mills Hospital | Mason, OH | $511.20 | not published |
| Mercy West Hospital | Cincinnati, OH | $511.20 | not published |
| Marcum Wallace Hospital | Irvine, KY | $511.20 | not published |
| UPMC Passavant-McCandless | Pittsburgh, PA | $512.40 | $0.51 – $0.51 |
| SUMMIT MEDICAL CENTER | MT JULIET, TN | $525.93 | $1.70 – $5.57 |
| HCA FLORIDA ENGLEWOOD HOSPITAL | ENGLEWOOD, FL | $529.91 | $4.52 – $4.52 |
| Providence Centralia Hospital | Centralia, WA | $531.72 | $1.18 – $5.40 |
| Providence St Peter Hospital | Olympia, WA | $531.74 | $1.18 – $2.83 |
| Sequoia Hospital | Redwood City, CA | $537.63 | $1.11 – $1,211.14 |
| AdventHealth Deland | Deland, FL | $548.30 | not published |
| Texas Health Hospital Mansfield | Mansfield, TX | $553.36 | $1.94 – $2.26 |
| Texas Health Huguley Hospital Fort Worth South | Burleson, TX | $553.36 | $1.94 – $2.26 |
| Mark Twain Medical Center | San Andreas, CA | $554.56 | $215.41 – $816.01 |
| Lourdes Hospital | Paducah, KY | $557.40 | not published |
| HCA HealthONE Rocky Mountain Children's at Presbyterian St. Luke's | Denver, CO | $569.25 | $1.85 – $3.47 |
| MercyOne Waterloo Medical Center | Waterloo, IA | $572.60 | $106.08 – $572.60 |
| MercyOne Dubuque Medical Center | Dubuque, IA | $572.60 | $106.08 – $572.60 |
| MercyOne New Hampton Medical Center | New Hampton, IA | $572.60 | $113.60 – $572.60 |
| MercyOne Dyersville Medical Center | Dyersville, IA | $572.60 | $113.60 – $644.52 |
| MercyOne Clinton Medical Center | Clinton, IA | $572.60 | $100.06 – $572.60 |
| MercyOne Oelwein Medical Center | Oelwein, IA | $572.60 | $113.60 – $572.60 |
| MercyOne Cedar Falls Medical Center | Cedar Falls, IA | $572.60 | $106.08 – $572.60 |
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