Methylnaltrexone 12 mg/0.6 ml subcutaneous injection (wrapper) cost at US hospitals
METHYLNALTREXONE 12 MG/0.6 ML SUBCUTANEOUS INJECTION (WRAPPER) · HCPCS J2212
$18.83
lowest cash price
$407.16
national median
$3,078.69
highest cash price
542
hospitals with a published cash price
Middle half of hospitals (25th–75th percentile) against the full range. The same procedure varies $18.83–$3,078.69 — the variation is the story.
Median cash price over time
Sep 1, 2025 ($765.83) → Sep 1, 2026 ($752.97)
By state
| State | Hospitals | Lowest cash | Median | Highest |
|---|---|---|---|---|
| Alaska | 3 | $587.36 | $587.36 | $831.04 |
| Arizona | 6 | $282.30 | $386.22 | $620.32 |
| Arkansas | 3 | $188.16 | $192.20 | $216.26 |
| California | 84 | $64.55 | $329.09 | $1,005.96 |
| Colorado | 13 | $569.25 | $2,161.47 | $2,161.47 |
| Florida | 73 | $233.00 | $1,092.49 | $3,078.69 |
| Georgia | 16 | $198.95 | $792.56 | $2,612.30 |
| Hawaii | 2 | $182.71 | $182.71 | $440.75 |
| Illinois | 15 | $281.91 | $433.12 | $991.90 |
| Indiana | 22 | $308.40 | $308.40 | $1,812.47 |
| Iowa | 25 | $84.93 | $572.60 | $858.90 |
| Kansas | 6 | $263.01 | $2,207.81 | $2,207.81 |
| Kentucky | 18 | $203.13 | $678.30 | $1,812.47 |
| Louisiana | 5 | $469.75 | $469.75 | $469.75 |
| Maine | 7 | $581.42 | $765.83 | $1,658.49 |
| Maryland | 2 | $150.00 | $150.00 | $150.00 |
| Michigan | 18 | $112.26 | $112.26 | $112.26 |
| Minnesota | 15 | $48.55 | $299.46 | $349.37 |
| Missouri | 16 | $188.16 | $202.31 | $263.01 |
| Montana | 2 | $343.29 | $343.29 | $343.29 |
| Nebraska | 12 | $119.16 | $326.38 | $660.52 |
| Nevada | 2 | $169.95 | $169.95 | $188.19 |
| New Hampshire | 1 | $1,729.79 | $1,729.79 | $1,729.79 |
| New Jersey | 21 | not published by hospital | not published by hospital | not published by hospital |
| New Mexico | 2 | $831.04 | $831.04 | $1,199.72 |
| New York | 17 | not published by hospital | not published by hospital | not published by hospital |
| North Carolina | 14 | $392.75 | $392.75 | $776.12 |
| North Dakota | 2 | $67.20 | $67.20 | $118.20 |
| Ohio | 57 | $362.86 | $582.48 | $2,059.56 |
| Oklahoma | 7 | $303.47 | $303.47 | $466.88 |
| Oregon | 12 | $247.56 | $493.10 | $499.52 |
| Pennsylvania | 25 | $160.20 | $234.60 | $1,122.60 |
| South Carolina | 10 | $616.00 | $616.00 | $1,053.57 |
| South Dakota | 5 | $73.99 | $93.32 | $392.80 |
| Tennessee | 26 | $59.14 | $139.55 | $1,654.94 |
| Texas | 107 | $18.83 | $432.83 | $1,364.33 |
| Virginia | 19 | $139.55 | $752.97 | $1,189.51 |
| Washington | 25 | $221.07 | $303.21 | $1,409.74 |
| West Virginia | 5 | $165.68 | $331.36 | $351.16 |
| Wisconsin | 12 | $368.90 | $368.90 | $368.90 |
All hospitals
| Hospital | Location | Cash price | Negotiated range |
|---|---|---|---|
| Ascension St. Vincent Evansville (St. Mary's Health, Inc.) | IN 47750|10388 Warrick Wellness Trail Newburgh, IN | $308.40 | $0.41 – $3.02 |
| Ascension St. Vincent Kokomo (St. Joseph Hospital & Health Center, Inc.) | Kokomo, IN | $308.40 | $0.41 – $3.02 |
| Ascension St. Vincent Carmel (St. Vincent Carmel Hospital, Inc.) | Carmel, IN | $308.40 | $0.41 – $3.02 |
| Ascension St. Vincent Heart Center (St. Vincent Heart Center of Indiana, LLC) | Carmel, IN | $308.40 | $0.41 – $3.02 |
| MercyOne Genesis Davenport Medical Center | Davenport, IA | $313.40 | not published |
| MercyOne Genesis Silvis Medical Center | Silvis, IL | $313.40 | $40.97 – $111.39 |
| MercyOne Genesis DeWitt Medical Center | DeWitt, IA | $313.40 | $43.53 – $93.47 |
| MercyOne Genesis Aledo Medical Center | Aledo, IL | $313.40 | $1.32 – $60.18 |
| St. Joseph's Behavioral Health Center | Stockton, CA | $322.05 | $13.40 – $107.20 |
| CHI Health Mercy Council Bluffs | Council Bluffs, IA | $326.38 | $1.34 – $660.51 |
| CHI Health Creighton University Medical Center - Bergan Mercy | Omaha, NE | $326.38 | $2.57 – $660.51 |
| Lasting Hope Recovery Center | Omaha, NE | $326.38 | $2.97 – $660.51 |
| CHI Health Immanuel | Omaha, NE | $326.38 | $2.57 – $660.51 |
| CHI Health Lakeside | Omaha, NE | $326.38 | $2.57 – $660.51 |
| CHI Health Midlands | Papillion, NE | $326.38 | $2.57 – $660.51 |
| Redwood City Medical Center | Redwood City, CA | $329.09 | not published |
| Oakland Medical Center | Oakland, CA | $329.09 | not published |
| Sacramento Medical Center | SACRAMENTO, CA | $329.09 | not published |
| San Leandro Medical Center | SAN LEANDRO, CA | $329.09 | not published |
| Santa Clara Medical Center | SANTA CLARA, CA | $329.09 | not published |
| San Rafael Medical Center | SAN RAFAEL, CA | $329.09 | not published |
| Santa Rosa Medical Center | SANTA ROSA, CA | $329.09 | not published |
| South San Francisco Medical Center | SOUTH SAN FRANCISCO, CA | $329.09 | not published |
| South Sacramento Medical Center | SACRAMENTO, CA | $329.09 | not published |
| Vacaville Medical Center | VACAVILLE, CA | $329.09 | not published |
| Walnut Creek Medical Center | WALNUT CREEK, CA | $329.09 | not published |
| Vallejo Medical Center | VALLEJO, CA | $329.09 | not published |
| Antioch Medical Center | ANTIOCH, CA | $329.09 | not published |
| Fremont Medical Center | FREMONT, CA | $329.09 | not published |
| Fresno Medical Center | FRESNO, CA | $329.09 | not published |
| Roseville Medical Center | ROSEVILLE, CA | $329.09 | not published |
| San Jose Medical Center | SAN JOSE, CA | $329.09 | not published |
| San Francisco Medical Center | SAN FRANCISCO, CA | $329.09 | not published |
| West Virginia University Hospitals | Morgantown, WV | $331.36 | $1.98 – $1.98 |
| Thomas Hospitals | South Charleston, WV | $331.38 | $1.98 – $1.98 |
| Uniontown Hospital | Uniontown, PA | $331.38 | $3.47 – $3.47 |
| St. Bernardine Medical Center | San Bernardino, CA | $337.00 | $0.71 – $829.84 |
| SONORA COMMUNITY HOSPITAL | Sonora, CA | $337.99 | $0.82 – $2,960.40 |
| Providence St Joseph Medical Center | Polson, MT | $343.29 | not published |
| St Patrick Hospital - Broadway Campus | Missoula, MT | $343.29 | not published |
| Texas Health Harris Methodist Hospital Alliance | Fort Worth, TX | $346.28 | $1.25 – $1.25 |
| Texas Health Arlington Memorial Hospital | Arlington, TX | $346.28 | $1.25 – $1.25 |
| Texas Health Presbyterian Hospital Allen | Allen, TX | $346.28 | $1.25 – $1.25 |
| Texas Health Center for Diagnostics and Surgery Plano | Plano, TX | $346.28 | $1.97 – $1.97 |
| Texas Health Harris Methodist Hospital Azle | Azle, TX | $346.28 | $1.97 – $1.97 |
| Texas Health Presbyterian Hospital Flower Mound | Flower Mound, TX | $346.28 | $1.97 – $1.97 |
| Texas Health Presbyterian Hospital Denton | Denton, TX | $346.28 | $1.25 – $1.25 |
| Texas Health Presbyterian Hospital Dallas | Dallas, TX | $346.28 | $1.25 – $1.25 |
| Texas Health Hospital Frisco | Frisco, TX | $346.28 | $1.25 – $1.25 |
| Texas Health Heart & Vascular Hospital Arlington | Arlington, TX | $346.28 | $1.97 – $1.97 |
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