Methylnaltrexone 12 mg/0.6 ml subcutaneous injection (wrapper) cost at US hospitals
METHYLNALTREXONE 12 MG/0.6 ML SUBCUTANEOUS INJECTION (WRAPPER) · HCPCS J2212
$18.83
lowest cash price
$407.16
national median
$3,078.69
highest cash price
542
hospitals with a published cash price
Middle half of hospitals (25th–75th percentile) against the full range. The same procedure varies $18.83–$3,078.69 — the variation is the story.
Median cash price over time
Sep 1, 2025 ($765.83) → Sep 1, 2026 ($752.97)
By state
| State | Hospitals | Lowest cash | Median | Highest |
|---|---|---|---|---|
| Alaska | 3 | $587.36 | $587.36 | $831.04 |
| Arizona | 6 | $282.30 | $386.22 | $620.32 |
| Arkansas | 3 | $188.16 | $192.20 | $216.26 |
| California | 84 | $64.55 | $329.09 | $1,005.96 |
| Colorado | 13 | $569.25 | $2,161.47 | $2,161.47 |
| Florida | 73 | $233.00 | $1,092.49 | $3,078.69 |
| Georgia | 16 | $198.95 | $792.56 | $2,612.30 |
| Hawaii | 2 | $182.71 | $182.71 | $440.75 |
| Illinois | 15 | $281.91 | $433.12 | $991.90 |
| Indiana | 22 | $308.40 | $308.40 | $1,812.47 |
| Iowa | 25 | $84.93 | $572.60 | $858.90 |
| Kansas | 6 | $263.01 | $2,207.81 | $2,207.81 |
| Kentucky | 18 | $203.13 | $678.30 | $1,812.47 |
| Louisiana | 5 | $469.75 | $469.75 | $469.75 |
| Maine | 7 | $581.42 | $765.83 | $1,658.49 |
| Maryland | 2 | $150.00 | $150.00 | $150.00 |
| Michigan | 18 | $112.26 | $112.26 | $112.26 |
| Minnesota | 15 | $48.55 | $299.46 | $349.37 |
| Missouri | 16 | $188.16 | $202.31 | $263.01 |
| Montana | 2 | $343.29 | $343.29 | $343.29 |
| Nebraska | 12 | $119.16 | $326.38 | $660.52 |
| Nevada | 2 | $169.95 | $169.95 | $188.19 |
| New Hampshire | 1 | $1,729.79 | $1,729.79 | $1,729.79 |
| New Jersey | 21 | not published by hospital | not published by hospital | not published by hospital |
| New Mexico | 2 | $831.04 | $831.04 | $1,199.72 |
| New York | 17 | not published by hospital | not published by hospital | not published by hospital |
| North Carolina | 14 | $392.75 | $392.75 | $776.12 |
| North Dakota | 2 | $67.20 | $67.20 | $118.20 |
| Ohio | 57 | $362.86 | $582.48 | $2,059.56 |
| Oklahoma | 7 | $303.47 | $303.47 | $466.88 |
| Oregon | 12 | $247.56 | $493.10 | $499.52 |
| Pennsylvania | 25 | $160.20 | $234.60 | $1,122.60 |
| South Carolina | 10 | $616.00 | $616.00 | $1,053.57 |
| South Dakota | 5 | $73.99 | $93.32 | $392.80 |
| Tennessee | 26 | $59.14 | $139.55 | $1,654.94 |
| Texas | 107 | $18.83 | $432.83 | $1,364.33 |
| Virginia | 19 | $139.55 | $752.97 | $1,189.51 |
| Washington | 25 | $221.07 | $303.21 | $1,409.74 |
| West Virginia | 5 | $165.68 | $331.36 | $351.16 |
| Wisconsin | 12 | $368.90 | $368.90 | $368.90 |
All hospitals
| Hospital | Location | Cash price | Negotiated range |
|---|---|---|---|
| St Francis Downtown | Greenville, SC | $941.42 | not published |
| HCA FLORIDA AVENTURA HOSPITAL | HIALEAH, FL | $959.00 | $3.47 – $3.47 |
| MEDICAL CITY MCKINNEY HOSPITAL | McKinney, TX | $991.05 | $3.31 – $8.77 |
| Northwestern Lake Forest Hospital DBA Northwestern Medicine Catherine Gratz Griffin Lake Forest Hospital | Lake Forest, IL | $991.90 | not published |
| WellSpan Ephrata Community Hospital | Ephrata, PA | $1,001.40 | $609.00 – $609.00 |
| Mercy Medical Center Mt. Shasta | Mt Shasta, CA | $1,005.96 | $73.44 – $299.88 |
| St Mary's Hospital | Richmond, VA | $1,012.79 | not published |
| UPMC Jameson | New Castle, PA | $1,024.20 | $0.51 – $1.45 |
| Adventhealth Manchester | Manchester, KY | $1,028.27 | not published |
| St Francis Eastside | Greenville, SC | $1,053.57 | not published |
| CJW Medical Center-Chippenham Hospital Campus | CHESTERFIELD, VA | $1,064.00 | $1.52 – $5.57 |
| Memorial Regional Hospital | Mechanicsville, VA | $1,070.56 | not published |
| MEDICAL CITY WEATHERFORD HOSPITAL | Weatherford, TX | $1,072.09 | $3.31 – $8.77 |
| HCA FLORIDA PASADENA HOSPITAL | South Pasadena, FL | $1,080.00 | $4.52 – $4.52 |
| HCA FLORIDA ST. PETERSBURG HOSPITAL | NORTH, FL | $1,080.00 | $4.52 – $4.52 |
| akron general | Akron, OH | $1,092.49 | $2.17 – $1,008.45 |
| avon hospital | Avon, OH | $1,092.49 | $3.33 – $1,008.45 |
| cleveland clinic florida weston hospital | Weston, FL | $1,092.49 | $4.11 – $952.43 |
| cleveland clinic childrens hospital for rehabilitation | Cleveland, OH | $1,092.49 | $72.53 – $1,008.45 |
| euclid hospital | Euclid, OH | $1,092.49 | $1.15 – $1,008.45 |
| fairview hospital | Cleveland, OH | $1,092.49 | $1.15 – $1,008.45 |
| lutheran hospital | Cleveland, OH | $1,092.49 | $3.33 – $1,008.45 |
| hillcrest hospital | Mayfield Heights, OH | $1,092.49 | $1.15 – $1,008.45 |
| lodi hospital | Lodi, OH | $1,092.49 | $69.50 – $1,008.45 |
| martin north hospital | Stuart, FL | $1,092.49 | $233.06 – $840.38 |
| marymount hospital | Garfield Heights, OH | $1,092.49 | $1.15 – $1,008.45 |
| indian river hospital | Vero Beach, FL | $1,092.49 | $262.20 – $896.40 |
| medina hospital | Medina, OH | $1,092.49 | $3.33 – $1,008.45 |
| mercy hospital | Canton, OH | $1,092.49 | $2.01 – $1,008.45 |
| south pointe hospital | Warrensville Heights, OH | $1,092.49 | $1.15 – $1,008.45 |
| Southside Regional Medical Center | Petersburg, VA | $1,114.75 | not published |
| WellSpan Gettysburg Hospital | Gettysburg, PA | $1,122.60 | $609.00 – $609.00 |
| MEDICAL CITY ARGYLE HOSPITAL | Argyle, TX | $1,123.99 | $3.31 – $8.77 |
| HCA HOUSTON NORTHWEST | SPRING, TX | $1,137.50 | $1.88 – $3.51 |
| HCA HOUSTON MEDICAL CENTER | Houston, TX | $1,151.66 | $1.88 – $3.51 |
| Waldo County General Hospital | Belfast, ME | $1,184.06 | $1.31 – $1,113.02 |
| St Francis Medical Center | Midlothian, VA | $1,189.51 | not published |
| CHRISTUS St. Vincent Regional Medical Center | Santa Fe, NM | $1,199.72 | $0.37 – $1.92 |
| MEDICAL CITY LEWISVILLE HOSPITAL | LEWISVILLE, TX | $1,212.05 | $3.31 – $8.77 |
| HCA FLORIDA LARGO HOSPITAL | LARGO, FL | $1,218.07 | $4.52 – $4.52 |
| HCA FLORIDA UNIVERSITY HOSPITAL | Davie, FL | $1,224.38 | $3.47 – $3.47 |
| HCA FLORIDA ST. LUCIE HOSPITAL | STUART, FL | $1,233.00 | $3.47 – $3.47 |
| HCA HealthONE BELMAR ER, A PART OF SWEDISH | LAKEWOOD, CO | $1,238.44 | $1.85 – $6.30 |
| Adventhealth Waterman | Tavares, FL | $1,255.05 | not published |
| Adventhealth Tampa | Tampa, FL | $1,280.82 | not published |
| SKYLINE MADISON CAMPUS | NASHVILLE, TN | $1,300.60 | $1.70 – $5.57 |
| St Ritas Medical Center | Lima, OH | $1,325.46 | not published |
| Baptist Hospital | MIAMI, FL | $1,329.90 | $79.75 – $414.90 |
| Bethesda Hospital East | BOYNTON BEACH, FL | $1,329.90 | $92.66 – $414.90 |
| Doctors Hospital | CORAL GABLES, FL | $1,329.90 | $80.68 – $414.90 |
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