Methylnaltrexone 12 mg/0.6 ml subcutaneous injection (wrapper) cost at US hospitals
METHYLNALTREXONE 12 MG/0.6 ML SUBCUTANEOUS INJECTION (WRAPPER) · HCPCS J2212
$18.83
lowest cash price
$407.16
national median
$3,078.69
highest cash price
542
hospitals with a published cash price
Middle half of hospitals (25th–75th percentile) against the full range. The same procedure varies $18.83–$3,078.69 — the variation is the story.
Median cash price over time
Sep 1, 2025 ($765.83) → Sep 1, 2026 ($752.97)
By state
| State | Hospitals | Lowest cash | Median | Highest |
|---|---|---|---|---|
| Alaska | 3 | $587.36 | $587.36 | $831.04 |
| Arizona | 6 | $282.30 | $386.22 | $620.32 |
| Arkansas | 3 | $188.16 | $192.20 | $216.26 |
| California | 84 | $64.55 | $329.09 | $1,005.96 |
| Colorado | 13 | $569.25 | $2,161.47 | $2,161.47 |
| Florida | 73 | $233.00 | $1,092.49 | $3,078.69 |
| Georgia | 16 | $198.95 | $792.56 | $2,612.30 |
| Hawaii | 2 | $182.71 | $182.71 | $440.75 |
| Illinois | 15 | $281.91 | $433.12 | $991.90 |
| Indiana | 22 | $308.40 | $308.40 | $1,812.47 |
| Iowa | 25 | $84.93 | $572.60 | $858.90 |
| Kansas | 6 | $263.01 | $2,207.81 | $2,207.81 |
| Kentucky | 18 | $203.13 | $678.30 | $1,812.47 |
| Louisiana | 5 | $469.75 | $469.75 | $469.75 |
| Maine | 7 | $581.42 | $765.83 | $1,658.49 |
| Maryland | 2 | $150.00 | $150.00 | $150.00 |
| Michigan | 18 | $112.26 | $112.26 | $112.26 |
| Minnesota | 15 | $48.55 | $299.46 | $349.37 |
| Missouri | 16 | $188.16 | $202.31 | $263.01 |
| Montana | 2 | $343.29 | $343.29 | $343.29 |
| Nebraska | 12 | $119.16 | $326.38 | $660.52 |
| Nevada | 2 | $169.95 | $169.95 | $188.19 |
| New Hampshire | 1 | $1,729.79 | $1,729.79 | $1,729.79 |
| New Jersey | 21 | not published by hospital | not published by hospital | not published by hospital |
| New Mexico | 2 | $831.04 | $831.04 | $1,199.72 |
| New York | 17 | not published by hospital | not published by hospital | not published by hospital |
| North Carolina | 14 | $392.75 | $392.75 | $776.12 |
| North Dakota | 2 | $67.20 | $67.20 | $118.20 |
| Ohio | 57 | $362.86 | $582.48 | $2,059.56 |
| Oklahoma | 7 | $303.47 | $303.47 | $466.88 |
| Oregon | 12 | $247.56 | $493.10 | $499.52 |
| Pennsylvania | 25 | $160.20 | $234.60 | $1,122.60 |
| South Carolina | 10 | $616.00 | $616.00 | $1,053.57 |
| South Dakota | 5 | $73.99 | $93.32 | $392.80 |
| Tennessee | 26 | $59.14 | $139.55 | $1,654.94 |
| Texas | 107 | $18.83 | $432.83 | $1,364.33 |
| Virginia | 19 | $139.55 | $752.97 | $1,189.51 |
| Washington | 25 | $221.07 | $303.21 | $1,409.74 |
| West Virginia | 5 | $165.68 | $331.36 | $351.16 |
| Wisconsin | 12 | $368.90 | $368.90 | $368.90 |
All hospitals
| Hospital | Location | Cash price | Negotiated range |
|---|---|---|---|
| St. Joseph Health Burleson Hospital | Caldwell, TX | $18.83 | $1.32 – $96.84 |
| St. Joseph Health Madison Hospital | Madisonville, TX | $18.83 | $1.32 – $96.84 |
| St. Joseph Health Grimes Hospital | Navasota, TX | $18.83 | $1.32 – $119.43 |
| St. Joseph Health College Station Hospital | College Station, TX | $18.83 | $1.32 – $91.46 |
| Sanford Thief River Falls Medical Center | Thief River Falls, MN | $48.55 | $20.84 – $54.61 |
| Sanford Behavioral Health Thief River Falls | Thief River Falls, MN | $48.55 | $20.84 – $54.61 |
| Sanford Bemidji Medical Center | Bemidji, MN | $58.17 | $1.17 – $53.08 |
| Sanford Bagley Medical Center | Bagley, MN | $58.47 | $17.69 – $65.77 |
| LeConte Medical Center | Sevierville, TN | $59.14 | $0.60 – $183.52 |
| Parkwest Medical Center | Knoxville, TN | $61.18 | $0.60 – $183.52 |
| Morristown-Hamblen Hospital Association | Morristown, TN | $61.18 | $0.60 – $183.52 |
| WHITE MEMORIAL MEDICAL CENTER | MONTEBELLO, CA | $64.55 | $0.87 – $1,255.10 |
| Cumberland Medical Center, Inc. | Crossville, TN | $65.25 | $0.72 – $183.52 |
| Sanford Medical Center Bismarck | Bismarck, ND | $67.20 | $15.44 – $43.83 |
| Roane County Medical Center | Harriman, TN | $67.29 | $0.60 – $183.52 |
| Fort Loudoun Medical Center | Lenoir City, TN | $67.29 | $0.60 – $183.52 |
| Fort Sanders Regional Medical Center | Knoxville, TN | $67.29 | $0.60 – $183.52 |
| Methodist Medical Center of Oak Ridge | Oak Ridge, TN | $67.29 | $0.60 – $183.52 |
| Sanford Vermillion Hospital | Vermillion, SD | $73.99 | $27.28 – $83.23 |
| Sanford Clear Lake Medical Center | Clear Lake, SD | $74.88 | $48.01 – $84.23 |
| Sanford Sheldon Medical Center | Sheldon, IA | $84.93 | $30.26 – $95.54 |
| Sanford Canton Inwood Medical Center | Canton, SD | $93.32 | $39.89 – $104.98 |
| Sanford Hospital Webster | Webster, SD | $98.07 | $38.49 – $110.32 |
| Sanford Luverne Medical Center | Luverne, MN | $98.68 | $29.86 – $111.02 |
| Sanford Worthington Medical Center | Worthington, MN | $99.65 | $1.15 – $112.10 |
| Henry Ford Rochester Hospital | Rochester, MI | $112.26 | $1.74 – $3.37 |
| Sanford Fargo Medical Center | Fargo, ND | $118.20 | $1.15 – $73.26 |
| CHI Health Nebraska Heart | Lincoln, NE | $119.16 | $2.57 – $212.40 |
| Hancock County Hospital | SNEEDVILLE, TN | $122.40 | $0.19 – $2.55 |
| CHI Health St. Elizabeth | Lincoln, NE | $129.52 | $2.57 – $207.22 |
| Bristol Regional Medical Center | BRISTOL, TN | $139.55 | $0.23 – $3.02 |
| Franklin Woods Community Hospital | JOHNSON CITY, TN | $139.55 | $0.34 – $2.55 |
| Greeneville Community Hospital | GREENEVILLE, TN | $139.55 | $0.14 – $2.55 |
| Hawkins County Memorial Hospital | ROGERSVILLE, TN | $139.55 | $0.19 – $2.55 |
| Holston Valley Medical Center | KINGSPORT, TN | $139.55 | $0.23 – $2.55 |
| Indian Path Community Hospital | KINGSPORT, TN | $139.55 | $0.34 – $3.29 |
| Johnson City Medical Center | JOHNSON CITY, TN | $139.55 | $0.34 – $2.55 |
| Johnston Memorial Hospital | ABINGDON, VA | $139.55 | $0.34 – $3.29 |
| Lonesome Pine Hospital | BIG STONE GAP, VA | $139.55 | $0.19 – $2.55 |
| UPMC Western Maryland | Cumberland, MD | $150.00 | $250.00 – $250.00 |
| CHI Health St. Francis | Grand Island, NE | $152.83 | $2.57 – $243.48 |
| CHI Health Good Samaritan | Kearney, NE | $158.01 | $2.57 – $240.89 |
| UPMC Community Osteopathic | Harrisburg, PA | $160.20 | $0.84 – $226.95 |
| UPMC Hanover | Hanover, PA | $160.20 | $1.85 – $8.43 |
| UPMC Lititz | Lititz, PA | $160.20 | $1.45 – $8.43 |
| UPMC Memorial | York, PA | $160.20 | $0.41 – $8.43 |
| UPMC Somerset | Somerset, PA | $160.20 | $0.50 – $0.50 |
| UPMC Carlisle | Carlisle, PA | $160.20 | $1.85 – $226.95 |
| Mercy General Hospital | Sacramento, CA | $161.11 | $1.15 – $140.00 |
| St. Luke's Health - The Vintage Hospital | Houston, TX | $163.20 | $1.05 – $97.93 |
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