Methotrexate therapeutic drug level cost at US hospitals
HC Methotrexate Tda · CPT 80204
$5.60
lowest cash price
$105.30
national median
$1,040.00
highest cash price
747
hospitals with a published cash price
Middle half of hospitals (25th–75th percentile) against the full range. The same procedure varies $5.60–$1,040.00 — the variation is the story.
Median cash price over time
Sep 1, 2025 ($84.75) → Sep 1, 2026 ($178.50)
By state
| State | Hospitals | Lowest cash | Median | Highest |
|---|---|---|---|---|
| Alaska | 5 | $46.02 | $48.36 | $355.68 |
| Arizona | 19 | $9.74 | $18.56 | $65.08 |
| Arkansas | 9 | $11.55 | $125.45 | $377.00 |
| California | 85 | $5.60 | $52.80 | $148.41 |
| Colorado | 9 | $26.68 | $218.93 | $551.85 |
| Florida | 78 | $17.00 | $180.05 | $1,016.00 |
| Georgia | 25 | $45.88 | $105.30 | $154.00 |
| Hawaii | 2 | $41.96 | $41.96 | $117.00 |
| Illinois | 42 | $33.00 | $159.60 | $478.80 |
| Indiana | 26 | $162.50 | $165.50 | $201.56 |
| Iowa | 29 | $47.40 | $77.60 | $352.00 |
| Kansas | 10 | $218.60 | $218.60 | $559.77 |
| Kentucky | 17 | $16.20 | $41.40 | $201.56 |
| Louisiana | 4 | not published by hospital | not published by hospital | not published by hospital |
| Maine | 7 | $84.75 | $137.90 | $290.15 |
| Maryland | 1 | not published by hospital | not published by hospital | not published by hospital |
| Michigan | 26 | $50.40 | $100.00 | $259.20 |
| Minnesota | 14 | $69.70 | $81.31 | $108.00 |
| Mississippi | 8 | $15.40 | $18.48 | $40.04 |
| Missouri | 18 | $29.15 | $253.50 | $1,011.17 |
| Montana | 2 | $60.80 | $60.80 | $80.00 |
| Nebraska | 11 | $63.44 | $118.86 | $239.70 |
| Nevada | 3 | $28.91 | $32.01 | $40.33 |
| New Hampshire | 1 | $274.60 | $274.60 | $274.60 |
| New Jersey | 22 | $38.57 | $42.43 | $48.50 |
| New Mexico | 2 | not published by hospital | not published by hospital | not published by hospital |
| New York | 20 | $33.60 | $38.57 | $126.22 |
| North Carolina | 15 | $146.80 | $146.80 | $262.50 |
| North Dakota | 2 | not published by hospital | not published by hospital | not published by hospital |
| Ohio | 66 | $39.60 | $81.60 | $1,040.00 |
| Oklahoma | 17 | $101.75 | $128.05 | $520.85 |
| Oregon | 9 | $41.60 | $155.55 | $155.55 |
| Pennsylvania | 23 | $67.20 | $133.60 | $615.00 |
| South Carolina | 10 | $111.00 | $145.00 | $693.00 |
| South Dakota | 2 | not published by hospital | not published by hospital | not published by hospital |
| Tennessee | 37 | $14.80 | $49.50 | $308.60 |
| Texas | 102 | $53.25 | $148.65 | $982.62 |
| Virginia | 37 | $48.53 | $262.50 | $914.00 |
| Washington | 32 | $22.40 | $91.58 | $148.72 |
| West Virginia | 17 | $16.20 | $322.50 | $516.00 |
| Wisconsin | 30 | $63.80 | $140.00 | $165.00 |
| Wyoming | 4 | $48.72 | $71.34 | $77.14 |
All hospitals
| Hospital | Location | Cash price | Negotiated range |
|---|---|---|---|
| Panorama Medical Center | PANORAMA CITY, CA | $71.76 | $27.00 – $27.00 |
| San Diego Clairemont Mesa Medical Center | SAN DIEGO, CA | $71.76 | $27.00 – $27.00 |
| Los Angeles Sunset Medical Center | LOS ANGELES, CA | $71.76 | $27.00 – $27.00 |
| Moreno Valley Medical Center | MORENO VALLEY, CA | $71.76 | $27.00 – $27.00 |
| HCA FLORIDA BLAKE HOSPITAL | BRADENTON, FL | $73.60 | $34.96 – $122.91 |
| St Anne Hospital | Toledo, OH | $73.80 | not published |
| Washakie Medical Center | Worland, WY | $74.47 | $55.68 – $112.52 |
| Platte County Hospital | Wheatland, WY | $77.14 | $55.68 – $112.52 |
| UnityPoint Health - Allen Hospital | Waterloo, IA | $77.60 | $23.14 – $58.33 |
| UnityPoint Health - Finley Hospital | Dubuque, IA | $77.60 | $3.50 – $66.42 |
| UnityPoint Health - Grinnell Regional Medical Center | Grinnell, IA | $77.60 | $23.14 – $50.14 |
| UnityPoint Health - Iowa Lutheran Hospital | Des Moines, IA | $77.60 | $21.75 – $58.33 |
| UnityPoint Health - Jones Regional Medical Center | Anamosa, IA | $77.60 | $23.14 – $73.65 |
| UnityPoint Health - Marshalltown | Marshalltown, IA | $77.60 | $23.14 – $50.14 |
| UnityPoint Health - St. Lukes Downtown | Sioux City, IA | $77.60 | $21.59 – $58.33 |
| UnityPoint Health - Trinity Bettendorf | Bettendorf, IA | $77.60 | $23.14 – $61.71 |
| UnityPoint Health - Trinity Moline | Rock Island, IL | $77.60 | $3.50 – $61.71 |
| UnityPoint Health - Trinity Muscatine | Muscatine, IA | $77.60 | $3.50 – $61.71 |
| UnityPoint Health - Trinity Regional Medical Center | Fort Dodge, IA | $77.60 | $23.14 – $70.58 |
| UnityPoint Health - St. Luke's Hospital | Cedar Rapids, IA | $77.60 | $23.14 – $58.33 |
| University Hospitals Conneaut Medical Center | Conneaut, OH | $78.00 | $59.00 – $92.58 |
| University Hospitals Geneva Medical Center | Geneva, OH | $78.00 | $69.00 – $92.58 |
| LeConte Medical Center | Sevierville, TN | $78.30 | $17.36 – $243.00 |
| Corewell Health Lakeland Watervliet | Watervliet, MI | $80.00 | $38.57 – $57.86 |
| Corewell Health Lakeland St. Joseph | St Joseph, MI | $80.00 | $38.57 – $57.86 |
| St Patrick Hospital - Broadway Campus | Missoula, MT | $80.00 | $38.96 – $119.07 |
| Morristown-Hamblen Hospital Association | Morristown, TN | $81.00 | $17.36 – $243.00 |
| HCA FLORIDA WESTSIDE HOSPITAL | PLANTATION, FL | $81.00 | $38.18 – $349.06 |
| Allina Health Faribault Medical Center | Faribualt, MN | $81.31 | $18.41 – $54.90 |
| Buffalo Hospital | Buffalo, MN | $81.31 | $18.41 – $54.90 |
| Cambridge Medical Center | Cambridge, MN | $81.31 | $18.41 – $54.90 |
| River Falls Area Hospital | River Falls, MN | $81.31 | $23.55 – $116.58 |
| Owatonna Hospital | Owatonna, MN | $81.31 | $18.41 – $54.90 |
| St Elizabeth Youngstown Hospital | Youngstown, OH | $81.60 | not published |
| St Elizabeth Boardman Hospital | Youngstown, OH | $81.60 | not published |
| St Joseph Warren Hospital | Warren, OH | $81.60 | not published |
| Advocate Illinois Masonic Medical Center | Chicago, IL | $82.50 | $38.57 – $175.60 |
| Advocate Sherman Hospital | Elgin, IL | $82.50 | $38.57 – $175.60 |
| Advocate South Suburban Hospital | Hazel Crest, IL | $82.50 | $38.57 – $175.60 |
| Advocate Trinity Hospital | Chicago, IL | $82.50 | $38.57 – $175.60 |
| Advocate Childrens Hospital - Park Ridge | Park Ridge, IL | $82.50 | $38.57 – $175.60 |
| Advocate Christ Medical Center | Oak Lawn, IL | $82.50 | $38.57 – $175.60 |
| Advocate Condell Medical Center | Libertyville, IL | $82.50 | $38.57 – $175.60 |
| Advocate Good Samaritan Hospital | Downers Grove, IL | $82.50 | $38.57 – $175.60 |
| WellSpan Good Samaritan Hospital | Lebanon, PA | $83.20 | $18.72 – $175.11 |
| Pen Bay Medical Center | Rockport, ME | $84.75 | $18.56 – $79.67 |
| Mid Coast Hospital | Brunswick, ME | $84.75 | $16.85 – $79.76 |
| Trinity Medical Center East | Steubenville, OH | $84.81 | $15.43 – $114.57 |
| Cumberland Medical Center, Inc. | Crossville, TN | $86.40 | $17.36 – $243.00 |
| St. Clare Hospital | Lakewood, WA | $86.45 | $38.57 – $224.94 |