Methotrexate therapeutic drug level cost at US hospitals
HC Methotrexate Tda · CPT 80204
$5.60
lowest cash price
$105.30
national median
$1,040.00
highest cash price
747
hospitals with a published cash price
Middle half of hospitals (25th–75th percentile) against the full range. The same procedure varies $5.60–$1,040.00 — the variation is the story.
Median cash price over time
Sep 1, 2025 ($84.75) → Sep 1, 2026 ($178.50)
By state
| State | Hospitals | Lowest cash | Median | Highest |
|---|---|---|---|---|
| Alaska | 5 | $46.02 | $48.36 | $355.68 |
| Arizona | 19 | $9.74 | $18.56 | $65.08 |
| Arkansas | 9 | $11.55 | $125.45 | $377.00 |
| California | 85 | $5.60 | $52.80 | $148.41 |
| Colorado | 9 | $26.68 | $218.93 | $551.85 |
| Florida | 78 | $17.00 | $180.05 | $1,016.00 |
| Georgia | 25 | $45.88 | $105.30 | $154.00 |
| Hawaii | 2 | $41.96 | $41.96 | $117.00 |
| Illinois | 42 | $33.00 | $159.60 | $478.80 |
| Indiana | 26 | $162.50 | $165.50 | $201.56 |
| Iowa | 29 | $47.40 | $77.60 | $352.00 |
| Kansas | 10 | $218.60 | $218.60 | $559.77 |
| Kentucky | 17 | $16.20 | $41.40 | $201.56 |
| Louisiana | 4 | not published by hospital | not published by hospital | not published by hospital |
| Maine | 7 | $84.75 | $137.90 | $290.15 |
| Maryland | 1 | not published by hospital | not published by hospital | not published by hospital |
| Michigan | 26 | $50.40 | $100.00 | $259.20 |
| Minnesota | 14 | $69.70 | $81.31 | $108.00 |
| Mississippi | 8 | $15.40 | $18.48 | $40.04 |
| Missouri | 18 | $29.15 | $253.50 | $1,011.17 |
| Montana | 2 | $60.80 | $60.80 | $80.00 |
| Nebraska | 11 | $63.44 | $118.86 | $239.70 |
| Nevada | 3 | $28.91 | $32.01 | $40.33 |
| New Hampshire | 1 | $274.60 | $274.60 | $274.60 |
| New Jersey | 22 | $38.57 | $42.43 | $48.50 |
| New Mexico | 2 | not published by hospital | not published by hospital | not published by hospital |
| New York | 20 | $33.60 | $38.57 | $126.22 |
| North Carolina | 15 | $146.80 | $146.80 | $262.50 |
| North Dakota | 2 | not published by hospital | not published by hospital | not published by hospital |
| Ohio | 66 | $39.60 | $81.60 | $1,040.00 |
| Oklahoma | 17 | $101.75 | $128.05 | $520.85 |
| Oregon | 9 | $41.60 | $155.55 | $155.55 |
| Pennsylvania | 23 | $67.20 | $133.60 | $615.00 |
| South Carolina | 10 | $111.00 | $145.00 | $693.00 |
| South Dakota | 2 | not published by hospital | not published by hospital | not published by hospital |
| Tennessee | 37 | $14.80 | $49.50 | $308.60 |
| Texas | 102 | $53.25 | $148.65 | $982.62 |
| Virginia | 37 | $48.53 | $262.50 | $914.00 |
| Washington | 32 | $22.40 | $91.58 | $148.72 |
| West Virginia | 17 | $16.20 | $322.50 | $516.00 |
| Wisconsin | 30 | $63.80 | $140.00 | $165.00 |
| Wyoming | 4 | $48.72 | $71.34 | $77.14 |
All hospitals
| Hospital | Location | Cash price | Negotiated range |
|---|---|---|---|
| CHI Memorial Hospital Hixson | Hixson, TN | $45.88 | $25.18 – $108.50 |
| Providence Seward Hospital | Seward, AK | $46.02 | not published |
| MercyOne Genesis DeWitt Medical Center | DeWitt, IA | $47.40 | $26.86 – $57.67 |
| MercyOne Genesis Aledo Medical Center | Aledo, IL | $47.40 | $26.71 – $44.36 |
| Jewish Hospital | Cincinnati, OH | $48.00 | not published |
| Anderson Hospital | Cincinnati, OH | $48.00 | not published |
| Clermont Hospital | Batavia, OH | $48.00 | not published |
| Kings Mills Hospital | Mason, OH | $48.00 | not published |
| Fairfield Hospital | Fairfield, OH | $48.00 | not published |
| Mercy West Hospital | Cincinnati, OH | $48.00 | not published |
| Providence Kodiak Island Medical Center | Kodiak, AK | $48.36 | not published |
| Childrens Specialized Hospital | Mountainside, NJ | $48.50 | $30.86 – $31.79 |
| Dickenson Community Hospital | CLINTWOOD, VA | $48.53 | $18.23 – $85.17 |
| Hancock County Hospital | SNEEDVILLE, TN | $48.53 | $14.21 – $85.17 |
| Lee County Community Hospital | PENNINGTON GAP, VA | $48.53 | $18.23 – $85.17 |
| Johnson County Community Hospital | MOUNTAIN CITY, TN | $48.53 | $13.80 – $85.17 |
| Banner Wyoming Medical Center | Casper, WY | $48.72 | $31.32 – $111.36 |
| Bristol Regional Medical Center | BRISTOL, TN | $49.50 | $12.93 – $92.57 |
| Franklin Woods Community Hospital | JOHNSON CITY, TN | $49.50 | $13.80 – $84.08 |
| Greeneville Community Hospital | GREENEVILLE, TN | $49.50 | $13.80 – $84.08 |
| Hawkins County Memorial Hospital | ROGERSVILLE, TN | $49.50 | $14.22 – $84.08 |
| Holston Valley Medical Center | KINGSPORT, TN | $49.50 | $12.56 – $92.57 |
| Indian Path Community Hospital | KINGSPORT, TN | $49.50 | $12.15 – $92.57 |
| Johnson City Medical Center | JOHNSON CITY, TN | $49.50 | $12.72 – $84.08 |
| Johnston Memorial Hospital | ABINGDON, VA | $49.50 | $12.75 – $84.08 |
| Lonesome Pine Hospital | BIG STONE GAP, VA | $49.50 | $13.14 – $92.57 |
| Russell County Hospital | LEBANON, VA | $49.50 | $12.75 – $84.08 |
| Smyth County Community Hospital | MARION, VA | $49.50 | $12.75 – $84.08 |
| Sycamore Shoals Hospital | ELIZABETHTON, TN | $49.50 | $13.80 – $84.08 |
| GREENVIEW REGIONAL HOSPITAL | BOWLING GREEN, KY | $49.59 | $37.26 – $39.73 |
| HCA FLORIDA SOUTH SHORE HOSPITAL | PARRISH, FL | $49.61 | $34.96 – $122.91 |
| Henry Ford Providence Novi Hospital | Novi, MI | $50.40 | $22.37 – $53.23 |
| ADVENTIST HEALTH MENDOCINO COAST | Fort Bragg, CA | $52.80 | $30.86 – $198.46 |
| Providence Sacred Heart Medical Center and Children's Hospital | Spokane, WA | $53.20 | $38.57 – $98.16 |
| Henry Ford Hospital | Detroit MI 48202 | 19401 Hubbard Dr., MI | $53.23 | $20.00 – $75.21 |
| Henry Ford West Bloomfield Hospital | West Bloomfield, MI | $53.23 | $20.00 – $62.87 |
| Henry Ford Wyandotte Hospital: | Wyandotte, MI | $53.23 | $20.00 – $62.87 |
| Henry Ford Macomb Hospital | Clinton Twp, MI | $53.23 | $20.00 – $62.87 |
| St. Luke's Health Memorial Lufkin | Lufkin, TX | $53.25 | $32.40 – $319.50 |
| St. Luke's Health Memorial Livingston | Livingston, TX | $53.25 | $32.40 – $319.50 |
| St. Luke's Health Memorial San Augustine | San Augustine, TX | $53.25 | $32.40 – $319.50 |
| Banner University Medical Center Tucson | Tucson, AZ | $53.30 | $38.57 – $92.80 |
| Banner Payson Medical Center | Payson, AZ | $54.52 | $38.57 – $104.40 |
| University Hospitals Samaritan Medical Center | Ashland, OH | $54.75 | $38.57 – $69.43 |
| Providence Mount Carmel Hospital | Colville, WA | $56.00 | not published |
| Covenant Hospital Plainview | Plainview, TX | $56.28 | $37.41 – $40.69 |
| MercyOne Genesis Davenport West Medical Center | Davenport, IA | $56.40 | $38.57 – $38.57 |
| Providence Valdez Medical Center | Valdez, AK | $59.28 | not published |
| Providence Mission Hospital - Mission Viejo | Mission Viejo, CA | $59.33 | $32.78 – $77.14 |
| Methodist Charlton Medical Center | Dallas, TX | $60.00 | $30.78 – $132.58 |