Hyaluronidase, human recombinant 150 unit/ml injection solution cost at US hospitals
HYALURONIDASE, HUMAN RECOMBINANT 150 UNIT/ML INJECTION SOLUTION · HCPCS J3473
$8.37
lowest cash price
$142.40
national median
$1,041.37
highest cash price
488
hospitals with a published cash price
Middle half of hospitals (25th–75th percentile) against the full range. The same procedure varies $8.37–$1,041.37 — the variation is the story.
Median cash price over time
Sep 1, 2025 ($323.33) → Sep 1, 2026 ($316.80)
By state
| State | Hospitals | Lowest cash | Median | Highest |
|---|---|---|---|---|
| Alaska | 4 | $232.90 | $237.22 | $309.23 |
| Arkansas | 3 | $172.28 | $172.28 | $368.50 |
| California | 50 | $61.79 | $66.54 | $188.21 |
| Colorado | 12 | not published by hospital | not published by hospital | not published by hospital |
| Florida | 47 | $57.50 | $311.00 | $926.71 |
| Georgia | 14 | $74.71 | $234.36 | $234.36 |
| Hawaii | 1 | $89.13 | $89.13 | $89.13 |
| Illinois | 24 | $109.35 | $196.35 | $805.70 |
| Indiana | 24 | $74.30 | $180.48 | $493.78 |
| Iowa | 21 | $89.61 | $236.10 | $236.10 |
| Kansas | 3 | $235.75 | $235.75 | $235.75 |
| Kentucky | 18 | $42.66 | $133.92 | $493.78 |
| Louisiana | 6 | not published by hospital | not published by hospital | not published by hospital |
| Maine | 7 | $190.92 | $282.86 | $544.60 |
| Maryland | 1 | $57.00 | $57.00 | $57.00 |
| Michigan | 13 | not published by hospital | not published by hospital | not published by hospital |
| Minnesota | 18 | $81.48 | $98.15 | $105.80 |
| Mississippi | 1 | $211.70 | $211.70 | $211.70 |
| Missouri | 18 | $130.50 | $168.66 | $235.75 |
| Montana | 2 | $207.69 | $207.69 | $256.37 |
| Nebraska | 12 | $23.51 | $189.00 | $382.50 |
| New Hampshire | 1 | $343.80 | $343.80 | $343.80 |
| New Jersey | 21 | not published by hospital | not published by hospital | not published by hospital |
| New Mexico | 1 | not published by hospital | not published by hospital | not published by hospital |
| New York | 20 | $61.54 | $66.33 | $132.28 |
| North Carolina | 13 | $29.63 | $142.40 | $142.40 |
| North Dakota | 4 | $94.43 | $98.63 | $167.04 |
| Ohio | 60 | $35.46 | $130.57 | $176.15 |
| Oklahoma | 13 | $87.69 | $87.69 | $272.02 |
| Oregon | 11 | $101.01 | $202.67 | $264.18 |
| Pennsylvania | 24 | $33.00 | $246.60 | $598.80 |
| South Carolina | 10 | $78.54 | $87.90 | $247.00 |
| South Dakota | 5 | $89.74 | $98.15 | $341.00 |
| Tennessee | 28 | $74.71 | $117.76 | $739.95 |
| Texas | 113 | $8.37 | $150.66 | $1,041.37 |
| Virginia | 25 | $38.56 | $117.76 | $893.00 |
| Washington | 25 | $16.52 | $122.87 | $412.23 |
| West Virginia | 5 | $83.56 | $83.56 | $225.00 |
| Wisconsin | 21 | $43.38 | $101.52 | $203.24 |
All hospitals
| Hospital | Location | Cash price | Negotiated range |
|---|---|---|---|
| UPMC Presbyterian | Pittsburgh, PA | $419.40 | $0.23 – $53.36 |
| LEWISGALE HOSPITAL-PULASKI | PULASKI, VA | $428.00 | $0.27 – $0.95 |
| Baptist Health Floyd | New Albany, IN | $493.78 | $0.37 – $5.21 |
| Baptist Health Hardin | Elizabethtown, KY | $493.78 | $0.43 – $6.94 |
| Baptist Health Corbin | Corbin, KY | $493.78 | $0.43 – $6.94 |
| Baptist Health La Grange | La Grange, KY | $493.78 | $0.43 – $6.94 |
| Baptist Health Lexington | Lexington, KY | $493.78 | $0.43 – $7.05 |
| Baptist Health Louisville | Louisville, KY | $493.78 | $0.38 – $6.94 |
| Baptist Health Paducah | Paducah, KY | $493.78 | $0.36 – $6.94 |
| WellSpan Gettysburg Hospital | Gettysburg, PA | $495.40 | $54.30 – $189.00 |
| HCA FLORIDA NORTHWEST HOSPITAL | MARGATE, FL | $508.00 | $0.35 – $0.59 |
| Northwestern Medicine Kishwaukee Hospital | DeKalb, IL | $542.32 | not published |
| Pen Bay Medical Center | Rockport, ME | $544.60 | $0.36 – $511.92 |
| HCA FLORIDA PALMS WEST HOSPITAL | LOXAHATCHEE, FL | $560.00 | $0.35 – $0.59 |
| WellSpan Good Samaritan Hospital | Lebanon, PA | $598.80 | $0.39 – $189.00 |
| HCA FLORIDA CITRUS HOSPITAL | Inverness, FL | $615.00 | $0.35 – $0.77 |
| MEDICAL CITY NORTH HILLS HOSPITAL | North Richland Hills, TX | $617.28 | $0.35 – $2.18 |
| NORTHCREST MEDICAL CENTER | SPRINGFIELD, TN | $621.49 | $0.44 – $0.95 |
| STONECREST MEDICAL CENTER | Smyrna, TN | $621.83 | $0.44 – $0.95 |
| HCA HOUSTON WEST | HOUSTON, TX | $627.00 | $0.36 – $0.87 |
| HCA FLORIDA BLAKE HOSPITAL | BRADENTON, FL | $652.00 | $0.35 – $0.77 |
| HCA FLORIDA UNIVERSITY HOSPITAL | Davie, FL | $654.00 | $0.59 – $0.59 |
| MEDICAL CITY FORT WORTH HOSPITAL | FT WORTH, TX | $660.06 | $0.35 – $2.18 |
| Dell Children's Medical Center (Ascension Seton) | Austin, TX | $665.00 | $0.36 – $0.36 |
| HCA FLORIDA LARGO HOSPITAL | LARGO, FL | $679.80 | $0.35 – $0.77 |
| HCA FLORIDA PASADENA HOSPITAL | South Pasadena, FL | $697.95 | $0.35 – $0.77 |
| HCA FLORIDA ST. PETERSBURG HOSPITAL | NORTH, FL | $697.95 | $0.35 – $0.77 |
| HENDERSONVILLE MEDICAL CENTER | HENDERSONVILLE, TN | $739.95 | $0.44 – $0.95 |
| HENRICO DOCTORS HOSPITAL | RICHMOND, VA | $744.00 | $0.31 – $0.95 |
| TRICITIES HOSPITAL | HOPEWELL, VA | $744.00 | $0.31 – $0.95 |
| HCA HOUSTON SOUTHEAST | PASADENA, TX | $747.07 | $0.36 – $0.87 |
| SPOTSYLVANIA REGIONAL MEDICAL CENTER | Fredericksburg, VA | $764.64 | $0.35 – $0.95 |
| Northwestern Medicine Central DuPage Hospital | IL 60190, IL | $805.70 | not published |
| RESTON HOSPITAL CENTER | VIENNA, VA | $892.68 | $0.33 – $0.95 |
| CJW Medical Center-Chippenham Hospital Campus | CHESTERFIELD, VA | $893.00 | $0.31 – $0.95 |
| Adventhealth Port Charlotte | Port Charlotte, FL | $926.71 | not published |
| HCA HOUSTON NORTHWEST | SPRING, TX | $1,035.30 | $0.36 – $0.87 |
| HCA HOUSTON KINGWOOD | HUMBLE, TX | $1,041.37 | $0.36 – $0.87 |
| OVERLAND PARK REGIONAL MEDICAL CENTER | SHAWNEE, KS | not published | $0.36 – $0.37 |
| MENORAH MEDICAL CENTER | Overland Park, KS | not published | $0.36 – $0.37 |
| LEE'S SUMMIT MEDICAL CENTER | Lee's Summit, MO | not published | $0.36 – $0.37 |
| CENTERPOINT MEDICAL CENTER | Independence, MO | not published | $0.36 – $0.37 |
| HCA FLORIDA WOODMONT HOSPITAL | TAMARAC, FL | not published | $0.35 – $0.59 |
| HCA FLORIDA WESTSIDE HOSPITAL | PLANTATION, FL | not published | $0.35 – $0.59 |
| HCA FLORIDA TWIN CITIES HOSPITAL | DEFUNIAK SPRINGS, FL | not published | $0.35 – $1.08 |
| HCA FLORIDA ST. LUCIE HOSPITAL | STUART, FL | not published | $0.35 – $0.59 |
| HCA FLORIDA SOUTH SHORE HOSPITAL | PARRISH, FL | not published | $0.35 – $0.36 |
| HCA FLORIDA OAK HILL HOSPITAL | BROOKSVILLE, FL | not published | $0.35 – $0.77 |
| HCA FLORIDA MERCY HOSPITAL | MIAMI, FL | not published | $0.35 – $0.59 |
| HCA FLORIDA LEHIGH HOSPITAL | LEHIGH ACRES, FL | not published | $0.35 – $0.77 |
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