Alteplase 100 mg infusion from pyxis vial cost at US hospitals
ALTEPLASE 100 MG INFUSION FROM PYXIS VIAL · HCPCS J2997
$556.56
lowest cash price
$15,857.45
national median
$102,964.26
highest cash price
530
hospitals with a published cash price
Middle half of hospitals (25th–75th percentile) against the full range. The same procedure varies $556.56–$102,964.26 — the variation is the story.
Median cash price over time
Sep 1, 2025 ($21,013.50) → Sep 1, 2026 ($21,257.00)
By state
| State | Hospitals | Lowest cash | Median | Highest |
|---|---|---|---|---|
| Alaska | 5 | $960.10 | $19,668.33 | $45,243.16 |
| Arizona | 4 | $8,025.26 | $8,742.97 | $30,343.35 |
| Arkansas | 8 | $8,219.50 | $17,732.73 | $37,806.50 |
| California | 77 | $570.46 | $13,614.60 | $31,630.68 |
| Colorado | 13 | $2,478.25 | $2,478.25 | $2,478.25 |
| Florida | 70 | $556.56 | $1,488.87 | $20,592.84 |
| Georgia | 15 | $2,312.61 | $2,336.68 | $43,507.20 |
| Hawaii | 1 | $19,012.53 | $19,012.53 | $19,012.53 |
| Illinois | 24 | $979.91 | $25,018.70 | $56,853.12 |
| Indiana | 19 | $1,611.20 | $21,257.00 | $87,556.86 |
| Iowa | 20 | $12,850.08 | $25,477.05 | $25,477.05 |
| Kansas | 5 | $1,863.51 | $1,863.51 | $1,863.51 |
| Kentucky | 25 | $748.42 | $32,310.00 | $87,556.86 |
| Louisiana | 4 | $2,559.30 | $2,559.30 | $2,559.30 |
| Maine | 7 | $834.51 | $14,052.42 | $26,765.42 |
| Maryland | 2 | $9,848.40 | $9,848.40 | $9,848.40 |
| Michigan | 15 | $630.01 | $630.01 | $4,598.72 |
| Minnesota | 15 | $4,197.25 | $12,473.57 | $13,925.31 |
| Mississippi | 1 | $10,982.86 | $10,982.86 | $10,982.86 |
| Missouri | 20 | $17,160.70 | $17,217.91 | $21,450.88 |
| Montana | 2 | $21,626.26 | $21,626.26 | $21,626.26 |
| Nebraska | 12 | $3,906.49 | $17,833.94 | $36,092.49 |
| Nevada | 3 | $1,797.84 | $2,600.22 | $3,627.63 |
| New Hampshire | 1 | $31,580.10 | $31,580.10 | $31,580.10 |
| New Jersey | 12 | not published by hospital | not published by hospital | not published by hospital |
| New Mexico | 2 | $1,358.41 | $1,358.41 | $2,819.32 |
| New York | 3 | $28,799.19 | $28,799.19 | $28,799.19 |
| North Carolina | 13 | $705.99 | $17,085.20 | $17,085.20 |
| North Dakota | 3 | $7,445.27 | $9,173.77 | $13,143.43 |
| Ohio | 64 | $8,580.35 | $31,563.16 | $102,964.26 |
| Oklahoma | 13 | $5,084.26 | $5,084.26 | $36,081.48 |
| Oregon | 12 | $806.03 | $23,342.81 | $26,431.24 |
| Pennsylvania | 19 | $612.00 | $5,517.60 | $40,758.00 |
| South Carolina | 11 | $73,130.99 | $73,130.99 | $81,843.35 |
| South Dakota | 5 | $12,473.57 | $12,473.57 | $23,176.60 |
| Tennessee | 26 | $4,048.17 | $8,997.49 | $11,037.54 |
| Texas | 113 | $604.61 | $15,857.45 | $45,243.16 |
| Virginia | 37 | $4,871.66 | $56,498.32 | $92,403.78 |
| Washington | 23 | $635.31 | $12,548.99 | $24,345.24 |
| West Virginia | 8 | $729.05 | $12,124.70 | $32,310.00 |
| Wisconsin | 8 | not published by hospital | not published by hospital | not published by hospital |
All hospitals
| Hospital | Location | Cash price | Negotiated range |
|---|---|---|---|
| Texas Health Harris Methodist Hospital Alliance | Fort Worth, TX | $17,424.72 | $49.13 – $344.58 |
| Texas Health Arlington Memorial Hospital | Arlington, TX | $17,424.72 | $49.13 – $344.58 |
| Texas Health Presbyterian Hospital Allen | Allen, TX | $17,424.72 | $49.13 – $344.58 |
| Texas Health Center for Diagnostics and Surgery Plano | Plano, TX | $17,424.72 | $77.11 – $344.58 |
| Texas Health Harris Methodist Hospital Azle | Azle, TX | $17,424.72 | $77.11 – $344.58 |
| Texas Health Presbyterian Hospital Flower Mound | Flower Mound, TX | $17,424.72 | $77.11 – $344.58 |
| Texas Health Presbyterian Hospital Denton | Denton, TX | $17,424.72 | $49.13 – $344.58 |
| Texas Health Presbyterian Hospital Dallas | Dallas, TX | $17,424.72 | $49.13 – $344.58 |
| Texas Health Hospital Frisco | Frisco, TX | $17,424.72 | $49.13 – $344.58 |
| Texas Health Heart & Vascular Hospital Arlington | Arlington, TX | $17,424.72 | $77.11 – $344.58 |
| Texas Health Presbyterian Hospital Kaufman | Kaufman, TX | $17,424.72 | $77.11 – $344.58 |
| Texas Health Harris Methodist Hospital Hurst-Euless-Bedford | Bedford, TX | $17,424.72 | $49.13 – $344.58 |
| Texas Health Presbyterian Hospital Plano | Plano, TX | $17,424.72 | $49.13 – $344.58 |
| Texas Health Hospital Rockwall | Rockwall, TX | $17,424.72 | $77.11 – $344.58 |
| Texas Health Harris Methodist Hospital Southlake | Southlake, TX | $17,424.72 | $77.11 – $344.58 |
| Texas Health Springwood Hospital Hurst-Euless-Bedford | Bedford, TX | $17,424.72 | $49.13 – $49.13 |
| Texas Health Harris Methodist Hospital Southwest Fort Worth | Fort Worth, TX | $17,424.72 | $49.13 – $344.58 |
| Texas Health Harris Methodist Hospital Fort Worth | Fort Worth, TX | $17,424.72 | $49.13 – $344.58 |
| Texas Health Harris Methodist Hospital Stephenville | Stephenville, TX | $17,424.72 | $77.11 – $344.58 |
| Texas Health Harris Methodist Hospital Cleburne | Cleburne, TX | $17,424.72 | $77.11 – $344.58 |
| Petaluma Valley Hospital | Petaluma, CA | $17,531.48 | $41.66 – $196.64 |
| Queen of The Valley Medical Center | Napa, CA | $17,531.48 | $45.10 – $196.64 |
| Providence St Joseph Hospital Eureka | Eureka, CA | $17,531.48 | $53.79 – $196.64 |
| Healdsburg Hospital | Healdsburg, CA | $17,531.48 | $92.10 – $182.96 |
| Redwood Memorial Hospital | Fortuna, CA | $17,531.48 | $53.92 – $188.30 |
| Santa Rosa Memorial Hospital | Santa Rosa, CA | $17,531.48 | $44.79 – $196.64 |
| Mercy Hospital Waldron | Waldron, AR | $17,732.73 | $1,781.50 – $13,857.00 |
| Mercy Hospital Boonville | Booneville, AR | $17,732.73 | $71.26 – $554.28 |
| Mercy Hospital Paris | Academy Paris, AR | $17,732.73 | $71.26 – $554.28 |
| Mercy Orthopedic Hospital Fort Smith | Fort Smith, AR | $17,732.73 | $71.26 – $698.12 |
| Sierra Nevada Memorial Hospital | Grass Valley, CA | $17,779.54 | $75.13 – $299.88 |
| CHI Health Mercy Council Bluffs | Council Bluffs, IA | $17,833.94 | $77.56 – $634.27 |
| CHI Health Creighton University Medical Center - Bergan Mercy | Omaha, NE | $17,833.94 | $77.56 – $634.27 |
| Lasting Hope Recovery Center | Omaha, NE | $17,833.94 | $86.75 – $634.27 |
| CHI Health Immanuel | Omaha, NE | $17,833.94 | $77.56 – $634.27 |
| CHI Health Lakeside | Omaha, NE | $17,833.94 | $77.56 – $634.27 |
| CHI Health Midlands | Papillion, NE | $17,833.94 | $77.56 – $634.27 |
| Kadlec Regional Medical Center | Richland, WA | $17,961.70 | $88.97 – $196.97 |
| St. Michael Medical Center | Silverdale, WA | $18,126.83 | $75.98 – $386.45 |
| West Virginia University Hospitals | Morgantown, WV | $18,191.03 | $64.08 – $417.68 |
| CHRISTUS Spohn Hospital Corpus Christi - Shoreline | Corpus Christi, TX | $18,390.36 | $88.97 – $285.65 |
| CHI Saint Joseph Health - Saint Joseph London | London, KY | $18,657.02 | $107.88 – $1,145.69 |
| Moanalua Medical Center | HONOLULU, HI | $19,012.53 | $94.00 – $94.00 |
| CHI Saint Joseph Health - Saint Joseph Mount Sterling | Mt. Sterling, KY | $19,161.31 | $107.88 – $1,145.69 |
| UPMC Kane | Kane, PA | $19,391.40 | $94.45 – $150.94 |
| MID-COLUMBIA MEDICAL CENTER | The Dalles, OR | $19,479.20 | $95.09 – $3,034.59 |
| Providence Alaska Medical Center | Anchorage, AK | $19,668.33 | $673.79 – $673.79 |
| Providence Valdez Medical Center | Valdez, AK | $19,668.33 | not published |
| Providence Kodiak Island Medical Center | Kodiak, AK | $19,668.33 | not published |
| Mercy Hospital Carthage | Carthage, MO | $20,020.82 | $96.74 – $274.92 |
Related drugs procedures
- Abatacept (with maltose) 250 mg intravenous solution from $141.66
- Abciximab injection from $354.77
- Abobotulinumtoxina from $51.15
- Acetaminophen 10 mg/ml soln 100 ml glass cont from $3.00
- Acetazolamide 500 mg solution for injection from $6.30
- Acetylcysteine 200 mg/ml (20 %) intravenous solution from $12.60