Alteplase 100 mg infusion from pyxis vial cost at US hospitals
ALTEPLASE 100 MG INFUSION FROM PYXIS VIAL · HCPCS J2997
$556.56
lowest cash price
$15,857.45
national median
$102,964.26
highest cash price
530
hospitals with a published cash price
Middle half of hospitals (25th–75th percentile) against the full range. The same procedure varies $556.56–$102,964.26 — the variation is the story.
Median cash price over time
Sep 1, 2025 ($21,013.50) → Sep 1, 2026 ($21,257.00)
By state
| State | Hospitals | Lowest cash | Median | Highest |
|---|---|---|---|---|
| Alaska | 5 | $960.10 | $19,668.33 | $45,243.16 |
| Arizona | 4 | $8,025.26 | $8,742.97 | $30,343.35 |
| Arkansas | 8 | $8,219.50 | $17,732.73 | $37,806.50 |
| California | 77 | $570.46 | $13,614.60 | $31,630.68 |
| Colorado | 13 | $2,478.25 | $2,478.25 | $2,478.25 |
| Florida | 70 | $556.56 | $1,488.87 | $20,592.84 |
| Georgia | 15 | $2,312.61 | $2,336.68 | $43,507.20 |
| Hawaii | 1 | $19,012.53 | $19,012.53 | $19,012.53 |
| Illinois | 24 | $979.91 | $25,018.70 | $56,853.12 |
| Indiana | 19 | $1,611.20 | $21,257.00 | $87,556.86 |
| Iowa | 20 | $12,850.08 | $25,477.05 | $25,477.05 |
| Kansas | 5 | $1,863.51 | $1,863.51 | $1,863.51 |
| Kentucky | 25 | $748.42 | $32,310.00 | $87,556.86 |
| Louisiana | 4 | $2,559.30 | $2,559.30 | $2,559.30 |
| Maine | 7 | $834.51 | $14,052.42 | $26,765.42 |
| Maryland | 2 | $9,848.40 | $9,848.40 | $9,848.40 |
| Michigan | 15 | $630.01 | $630.01 | $4,598.72 |
| Minnesota | 15 | $4,197.25 | $12,473.57 | $13,925.31 |
| Mississippi | 1 | $10,982.86 | $10,982.86 | $10,982.86 |
| Missouri | 20 | $17,160.70 | $17,217.91 | $21,450.88 |
| Montana | 2 | $21,626.26 | $21,626.26 | $21,626.26 |
| Nebraska | 12 | $3,906.49 | $17,833.94 | $36,092.49 |
| Nevada | 3 | $1,797.84 | $2,600.22 | $3,627.63 |
| New Hampshire | 1 | $31,580.10 | $31,580.10 | $31,580.10 |
| New Jersey | 12 | not published by hospital | not published by hospital | not published by hospital |
| New Mexico | 2 | $1,358.41 | $1,358.41 | $2,819.32 |
| New York | 3 | $28,799.19 | $28,799.19 | $28,799.19 |
| North Carolina | 13 | $705.99 | $17,085.20 | $17,085.20 |
| North Dakota | 3 | $7,445.27 | $9,173.77 | $13,143.43 |
| Ohio | 64 | $8,580.35 | $31,563.16 | $102,964.26 |
| Oklahoma | 13 | $5,084.26 | $5,084.26 | $36,081.48 |
| Oregon | 12 | $806.03 | $23,342.81 | $26,431.24 |
| Pennsylvania | 19 | $612.00 | $5,517.60 | $40,758.00 |
| South Carolina | 11 | $73,130.99 | $73,130.99 | $81,843.35 |
| South Dakota | 5 | $12,473.57 | $12,473.57 | $23,176.60 |
| Tennessee | 26 | $4,048.17 | $8,997.49 | $11,037.54 |
| Texas | 113 | $604.61 | $15,857.45 | $45,243.16 |
| Virginia | 37 | $4,871.66 | $56,498.32 | $92,403.78 |
| Washington | 23 | $635.31 | $12,548.99 | $24,345.24 |
| West Virginia | 8 | $729.05 | $12,124.70 | $32,310.00 |
| Wisconsin | 8 | not published by hospital | not published by hospital | not published by hospital |
All hospitals
| Hospital | Location | Cash price | Negotiated range |
|---|---|---|---|
| OSF Saint Anthony's Health Center | Alton, IL | not published | $95.09 – $96.99 |
| OSF Saint Anthony Medical Center | Rockford, IL | not published | $86.12 – $332.82 |
| MEDICAL CITY ARGYLE HOSPITAL | Argyle, TX | not published | $92.24 – $569.70 |
| CHRISTUS St. Michael Hospital - Atlanta | Atlanta, TX | not published | $35.63 – $179.62 |
| CHRISTUS Spohn Hospital - Kleberg | Kingsville, TX | not published | $0.06 – $285.65 |
| CHRISTUS Spohn Hospital - Beeville | Beeville, TX | not published | $91.46 – $285.65 |
| CHRISTUS Spohn Hospital - Alice | Alice, TX | not published | $91.46 – $285.65 |
| CHRISTUS Southeast Texas Jasper Memorial | Jasper, TX | not published | $91.46 – $184.56 |
| CHRISTUS Trinity Mother Frances Hospital - Winnsboro | Winnsboro, TX | not published | $64.38 – $91.46 |
| CHRISTUS Trinity Mother Frances Hospital - Jacksonville | Jacksonville, TX | not published | $64.38 – $91.46 |
| SSM Health Ripon Community Hospital | Ripon, WI | not published | $99.05 – $249.05 |
| SSM Health Monroe Hospital | Monroe, WI | not published | $91.46 – $249.00 |
| Monmouth Medical Center Southern Campus | Lakewood, NJ | not published | $81.40 – $198.96 |
| SSM Health St. Anthony Hospital - Shawnee | Shawnee, OK | not published | $98.59 – $192.24 |
| Monmouth Medical Center | Long Branch, NJ | not published | $81.40 – $201.51 |
| Jersey City Medical Center | Jersey City, NJ | not published | $44.18 – $214.38 |
| SSM Health St. Joseph Hospital - Lake Saint Louis | Lake Saint Louis, MO | not published | $98.59 – $155.71 |
| Sanford Aberdeen Medical Center | Aberdeen, SD | not published | $89.72 – $99.17 |
| SSM Health St. Mary's Hospital - St. Louis | Richmond Heights, MO | not published | $98.59 – $155.71 |
| Newark Beth Israel Medical Center | Newark, NJ | not published | $81.40 – $204.23 |
| SSM Health St. Joseph Hospital - St. Charles | Saint Charles, MO | not published | $98.59 – $155.71 |
| Clara Maass Medical Center | Belleville, NJ | not published | $81.40 – $204.23 |
| Community Medical Center | Toms River, NJ | not published | $81.40 – $198.96 |
| SSM Health St. Mary's Hospital - Madison | Madison, WI | not published | $73.94 – $178.89 |
| SSM Health St. Anthony Hospital - Midwest | Midwest City, OK | not published | $98.59 – $192.24 |
| MEDICAL CITY ARLINGTON HOSPITAL | RED OAK, TX | not published | $92.24 – $569.70 |
| Trinitas Regional Medical Center | Elizabeth, NJ | not published | $34.14 – $198.96 |
| Wellstar Windy Hill Hospital | Marietta, GA | not published | $91.47 – $233.94 |
| Garrett Regional Medical Center | Oakland, MD | not published | not published |
| MEDICAL CITY WEATHERFORD HOSPITAL | Weatherford, TX | not published | $91.46 – $627.95 |
| OSF Little Company of Mary Medical Center | Evergreen Park, IL | not published | $91.46 – $176.87 |
| HCA FLORIDA SOUTH SHORE HOSPITAL | PARRISH, FL | not published | $92.24 – $95.09 |
| OSF Sacred Heart Medical Center – Urbana | Danville, IL | not published | $95.09 – $111.58 |
| OVERLAND PARK REGIONAL MEDICAL CENTER | SHAWNEE, KS | not published | $93.83 – $97.58 |
| Sentara Norfolk General Hospital | Norfolk, VA | not published | $96.34 – $99.17 |
| Sentara Northern Virginia Medical Center | Woodbridge, VA | not published | $96.34 – $124.95 |
| MEDICAL CITY MCKINNEY HOSPITAL | McKinney, TX | not published | $88.72 – $569.70 |
| Sentara Williamsburg Regional Medical Center | Williamsburg, VA | not published | $96.34 – $99.17 |
| Sentara CarePlex Hospital | Hampton, VA | not published | $96.34 – $99.17 |
| Wellstar West Georgia Medical Center | Lagrange, GA | not published | $94.45 – $233.94 |
| Wellstar Sylvan Grove Hospital | Jackson, GA | not published | $174.36 – $307.84 |
| Wellstar Spalding Regional Hospital | Griffin, GA | not published | $94.45 – $233.94 |
| Wellstar Paulding Hospital | Hiram, GA | not published | $94.45 – $233.94 |
| Sentara Obici Hospital | Suffolk, VA | not published | $96.34 – $99.17 |
| Wellstar North Fulton Hospital | Roswell, GA | not published | $94.45 – $233.94 |
| Corewell Health Wayne | Wayne, MI | not published | $31.53 – $127.50 |
| Corewell Health Troy | Troy, MI | not published | $31.53 – $128.70 |
| Corewell Health Trenton | Trenton, MI | not published | $31.53 – $127.50 |
| Corewell Health Taylor | Taylor, MI | not published | $31.53 – $127.50 |
| Sentara Princess Anne Hospital | Virginia Beach, VA | not published | $96.34 – $99.17 |
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