Alpha-1-proteinase inhibitor (human) 1,000 mg (+/-) IV solution cost at US hospitals
ALPHA-1-PROTEINASE INHIBITOR (HUMAN) 1,000 MG (+/-) IV SOLUTION · HCPCS J0256
$3.25
lowest cash price
$13.14
national median
$378.00
highest cash price
218
hospitals with a published cash price
Middle half of hospitals (25th–75th percentile) against the full range. The same procedure varies $3.25–$378.00 — the variation is the story.
Median cash price over time
Sep 1, 2025 ($71.68) → Sep 1, 2026 ($4.94)
By state
| State | Hospitals | Lowest cash | Median | Highest |
|---|---|---|---|---|
| Alaska | 1 | not published by hospital | not published by hospital | not published by hospital |
| Arizona | 1 | $7.26 | $7.26 | $7.26 |
| California | 52 | $3.98 | $4.28 | $19.69 |
| Colorado | 11 | $53.00 | $53.00 | $135.53 |
| Florida | 53 | $3.25 | $3.25 | $49.75 |
| Georgia | 19 | $13.53 | $13.53 | $13.53 |
| Hawaii | 1 | $5.74 | $5.74 | $5.74 |
| Illinois | 27 | $9.62 | $38.29 | $279.81 |
| Iowa | 18 | $9.56 | $9.76 | $48.76 |
| Kansas | 5 | not published by hospital | not published by hospital | not published by hospital |
| Kentucky | 10 | $3.60 | $114.82 | $157.78 |
| Louisiana | 6 | not published by hospital | not published by hospital | not published by hospital |
| Maine | 3 | $71.68 | $71.68 | $71.68 |
| Maryland | 1 | not published by hospital | not published by hospital | not published by hospital |
| Michigan | 17 | $7.41 | $7.41 | $7.41 |
| Minnesota | 8 | not published by hospital | not published by hospital | not published by hospital |
| Missouri | 14 | not published by hospital | not published by hospital | not published by hospital |
| Montana | 1 | not published by hospital | not published by hospital | not published by hospital |
| Nebraska | 7 | $41.79 | $41.79 | $84.58 |
| New Jersey | 21 | $4.94 | $5.19 | $5.19 |
| New Mexico | 2 | not published by hospital | not published by hospital | not published by hospital |
| New York | 19 | $4.94 | $4.94 | $36.00 |
| North Carolina | 13 | $22.78 | $22.78 | $22.78 |
| North Dakota | 2 | not published by hospital | not published by hospital | not published by hospital |
| Ohio | 29 | $10.15 | $10.15 | $10.15 |
| Oklahoma | 8 | $13.14 | $13.14 | $13.14 |
| Oregon | 4 | $6.51 | $6.51 | $6.51 |
| Pennsylvania | 21 | $29.80 | $51.00 | $378.00 |
| South Carolina | 8 | not published by hospital | not published by hospital | not published by hospital |
| South Dakota | 5 | not published by hospital | not published by hospital | not published by hospital |
| Tennessee | 9 | not published by hospital | not published by hospital | not published by hospital |
| Texas | 82 | $5.52 | $18.72 | $26.25 |
| Virginia | 21 | not published by hospital | not published by hospital | not published by hospital |
| Washington | 12 | $7.36 | $7.45 | $10.46 |
| West Virginia | 1 | $3.60 | $3.60 | $3.60 |
| Wisconsin | 23 | $6.53 | $9.62 | $17.07 |
All hospitals
| Hospital | Location | Cash price | Negotiated range |
|---|---|---|---|
| Baptist Hospital | MIAMI, FL | $3.25 | $0.87 – $827.77 |
| Bethesda Hospital East | BOYNTON BEACH, FL | $3.25 | $1.41 – $827.77 |
| Doctors Hospital | CORAL GABLES, FL | $3.25 | $0.88 – $825.36 |
| Baptist Health Hospital Doral | SOUTH MIAMI, FL | $3.25 | $0.87 – $825.36 |
| Fishermens Community Hospital | MARATHON, FL | $3.25 | $0.84 – $825.36 |
| Homestead Hospital | HOMESTEAD, FL | $3.25 | $0.85 – $802.44 |
| Mariners Hospital | TAVERNIER, FL | $3.25 | $0.87 – $825.36 |
| West Kendall Baptist Hospital | MIAMI, FL | $3.25 | $0.86 – $825.36 |
| Beckley ARH Hospital | Beckley, WV | $3.60 | $5.14 – $5.46 |
| Whitesburg ARH Hospital | Whitesburg, KY | $3.60 | $0.61 – $5.46 |
| Harlan ARH Hospital | KY 40831, KY | $3.60 | $0.61 – $5.46 |
| Hazard ARH Regional Medical Center | Hazard, KY | $3.60 | $0.61 – $5.46 |
| Orange County Anaheim Medical Center | Anaheim, CA | $3.98 | $5.18 – $5.18 |
| Baldwin Park Medical Center | BALDWIN PARK, CA | $3.98 | $5.18 – $5.18 |
| Downey Medical Center | Downey, CA | $3.98 | $5.18 – $5.18 |
| San Bernardino - Fontana Medical Center | FONTANA, CA | $3.98 | $5.18 – $5.18 |
| Riverside Medical Center | RIVERSIDE, CA | $3.98 | $5.18 – $5.18 |
| South Bay Medical Center | HARBOR CITY, CA | $3.98 | $5.18 – $5.18 |
| San Marcos Medical Center | SAN MARCOS, CA | $3.98 | $5.18 – $5.18 |
| West Los Angeles Medical Center | LOS ANGELES, CA | $3.98 | $5.18 – $5.18 |
| Woodland Hills Medical Center | WOODLAND HILLS, CA | $3.98 | $5.18 – $5.18 |
| Panorama Medical Center | PANORAMA CITY, CA | $3.98 | $5.18 – $5.18 |
| San Diego Clairemont Mesa Medical Center | SAN DIEGO, CA | $3.98 | $5.18 – $5.18 |
| Los Angeles Sunset Medical Center | LOS ANGELES, CA | $3.98 | $5.18 – $5.18 |
| Moreno Valley Medical Center | MORENO VALLEY, CA | $3.98 | $5.18 – $5.18 |
| Redwood City Medical Center | Redwood City, CA | $4.28 | $5.18 – $5.18 |
| Oakland Medical Center | Oakland, CA | $4.28 | $5.18 – $5.18 |
| Sacramento Medical Center | SACRAMENTO, CA | $4.28 | $5.18 – $5.18 |
| San Leandro Medical Center | SAN LEANDRO, CA | $4.28 | $5.18 – $5.18 |
| Santa Clara Medical Center | SANTA CLARA, CA | $4.28 | $5.18 – $5.18 |
| San Rafael Medical Center | SAN RAFAEL, CA | $4.28 | $5.18 – $5.18 |
| Santa Rosa Medical Center | SANTA ROSA, CA | $4.28 | $5.18 – $5.18 |
| South San Francisco Medical Center | SOUTH SAN FRANCISCO, CA | $4.28 | $5.18 – $5.18 |
| South Sacramento Medical Center | SACRAMENTO, CA | $4.28 | $5.18 – $5.18 |
| Vacaville Medical Center | VACAVILLE, CA | $4.28 | $5.18 – $5.18 |
| Walnut Creek Medical Center | WALNUT CREEK, CA | $4.28 | $5.18 – $5.18 |
| Vallejo Medical Center | VALLEJO, CA | $4.28 | $5.18 – $5.18 |
| Antioch Medical Center | ANTIOCH, CA | $4.28 | $5.18 – $5.18 |
| Fremont Medical Center | FREMONT, CA | $4.28 | $5.18 – $5.18 |
| Fresno Medical Center | FRESNO, CA | $4.28 | $5.18 – $5.18 |
| Roseville Medical Center | ROSEVILLE, CA | $4.28 | $5.18 – $5.18 |
| San Jose Medical Center | SAN JOSE, CA | $4.28 | $5.18 – $5.18 |
| San Francisco Medical Center | SAN FRANCISCO, CA | $4.28 | $5.18 – $5.18 |
| Woodhull Medical Center | Brooklyn, NY | $4.94 | $3.95 – $10.26 |
| Lincoln Medical Center | Bronx, NY | $4.94 | $3.95 – $10.26 |
| Kings County Hospital Center | Brooklyn, NY | $4.94 | $3.95 – $10.26 |
| Palisades Medical Center | North Bergen, NJ | $4.94 | $4.41 – $9.77 |
| Metropolitan Hospital Center | New York, NY | $4.94 | $3.95 – $10.26 |
| Queens Hospital Center | Jamaica, NY | $4.94 | $3.95 – $10.26 |
| Elmhurst Hospital Center | NY 11373, NY | $4.94 | $3.95 – $10.26 |
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